BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

913 related articles for article (PubMed ID: 29046453)

  • 1. Murine Hepatitis Virus nsp14 Exoribonuclease Activity Is Required for Resistance to Innate Immunity.
    Case JB; Li Y; Elliott R; Lu X; Graepel KW; Sexton NR; Smith EC; Weiss SR; Denison MR
    J Virol; 2018 Jan; 92(1):. PubMed ID: 29046453
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mutagenesis of Coronavirus nsp14 Reveals Its Potential Role in Modulation of the Innate Immune Response.
    Becares M; Pascual-Iglesias A; Nogales A; Sola I; Enjuanes L; Zuñiga S
    J Virol; 2016 Jun; 90(11):5399-5414. PubMed ID: 27009949
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Proofreading-Deficient Coronaviruses Adapt for Increased Fitness over Long-Term Passage without Reversion of Exoribonuclease-Inactivating Mutations.
    Graepel KW; Lu X; Case JB; Sexton NR; Smith EC; Denison MR
    mBio; 2017 Nov; 8(6):. PubMed ID: 29114026
    [TBL] [Abstract][Full Text] [Related]  

  • 4. High fidelity of murine hepatitis virus replication is decreased in nsp14 exoribonuclease mutants.
    Eckerle LD; Lu X; Sperry SM; Choi L; Denison MR
    J Virol; 2007 Nov; 81(22):12135-44. PubMed ID: 17804504
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mutagenesis of S-Adenosyl-l-Methionine-Binding Residues in Coronavirus nsp14 N7-Methyltransferase Demonstrates Differing Requirements for Genome Translation and Resistance to Innate Immunity.
    Case JB; Ashbrook AW; Dermody TS; Denison MR
    J Virol; 2016 Aug; 90(16):7248-7256. PubMed ID: 27252528
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Small-Molecule Antiviral β-d-
    Agostini ML; Pruijssers AJ; Chappell JD; Gribble J; Lu X; Andres EL; Bluemling GR; Lockwood MA; Sheahan TP; Sims AC; Natchus MG; Saindane M; Kolykhalov AA; Painter GR; Baric RS; Denison MR
    J Virol; 2019 Dec; 93(24):. PubMed ID: 31578288
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mutations in coronavirus nonstructural protein 10 decrease virus replication fidelity.
    Smith EC; Case JB; Blanc H; Isakov O; Shomron N; Vignuzzi M; Denison MR
    J Virol; 2015 Jun; 89(12):6418-26. PubMed ID: 25855750
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Coronaviruses lacking exoribonuclease activity are susceptible to lethal mutagenesis: evidence for proofreading and potential therapeutics.
    Smith EC; Blanc H; Surdel MC; Vignuzzi M; Denison MR
    PLoS Pathog; 2013 Aug; 9(8):e1003565. PubMed ID: 23966862
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Proteolytic Processing of the Coronavirus Replicase Nonstructural Protein 14 Exonuclease Is Not Required for Virus Replication but Alters RNA Synthesis and Viral Fitness.
    Anderson-Daniels J; Gribble J; Denison M
    J Virol; 2022 Aug; 96(16):e0084122. PubMed ID: 35924922
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The Enzymatic Activity of the nsp14 Exoribonuclease Is Critical for Replication of MERS-CoV and SARS-CoV-2.
    Ogando NS; Zevenhoven-Dobbe JC; van der Meer Y; Bredenbeek PJ; Posthuma CC; Snijder EJ
    J Virol; 2020 Nov; 94(23):. PubMed ID: 32938769
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease.
    Agostini ML; Andres EL; Sims AC; Graham RL; Sheahan TP; Lu X; Smith EC; Case JB; Feng JY; Jordan R; Ray AS; Cihlar T; Siegel D; Mackman RL; Clarke MO; Baric RS; Denison MR
    mBio; 2018 Mar; 9(2):. PubMed ID: 29511076
    [TBL] [Abstract][Full Text] [Related]  

  • 12. N7-Methylation of the Coronavirus RNA Cap Is Required for Maximal Virulence by Preventing Innate Immune Recognition.
    Pan R; Kindler E; Cao L; Zhou Y; Zhang Z; Liu Q; Ebert N; Züst R; Sun Y; Gorbalenya AE; Perlman S; Thiel V; Chen Y; Guo D
    mBio; 2022 Feb; 13(1):e0366221. PubMed ID: 35073761
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Porcine Epidemic Diarrhea Virus Deficient in RNA Cap Guanine-N-7 Methylation Is Attenuated and Induces Higher Type I and III Interferon Responses.
    Lu Y; Cai H; Lu M; Ma Y; Li A; Gao Y; Zhou J; Gu H; Li J; Gu J
    J Virol; 2020 Jul; 94(16):. PubMed ID: 32461321
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Homology-Based Identification of a Mutation in the Coronavirus RNA-Dependent RNA Polymerase That Confers Resistance to Multiple Mutagens.
    Sexton NR; Smith EC; Blanc H; Vignuzzi M; Peersen OB; Denison MR
    J Virol; 2016 Aug; 90(16):7415-7428. PubMed ID: 27279608
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Selective Packaging in Murine Coronavirus Promotes Virulence by Limiting Type I Interferon Responses.
    Athmer J; Fehr AR; Grunewald ME; Qu W; Wheeler DL; Graepel KW; Channappanavar R; Sekine A; Aldabeeb DS; Gale M; Denison MR; Perlman S
    mBio; 2018 May; 9(3):. PubMed ID: 29717007
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The coronavirus proofreading exoribonuclease mediates extensive viral recombination.
    Gribble J; Stevens LJ; Agostini ML; Anderson-Daniels J; Chappell JD; Lu X; Pruijssers AJ; Routh AL; Denison MR
    PLoS Pathog; 2021 Jan; 17(1):e1009226. PubMed ID: 33465137
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Coronavirus genomic nsp14-ExoN, structure, role, mechanism, and potential application as a drug target.
    Tahir M
    J Med Virol; 2021 Jul; 93(7):4258-4264. PubMed ID: 33837972
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Fitness Barriers Limit Reversion of a Proofreading-Deficient Coronavirus.
    Graepel KW; Agostini ML; Lu X; Sexton NR; Denison MR
    J Virol; 2019 Oct; 93(20):. PubMed ID: 31341046
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Antagonism of dsRNA-Induced Innate Immune Pathways by NS4a and NS4b Accessory Proteins during MERS Coronavirus Infection.
    Comar CE; Goldstein SA; Li Y; Yount B; Baric RS; Weiss SR
    mBio; 2019 Mar; 10(2):. PubMed ID: 30914508
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure and dynamics of SARS-CoV-2 proofreading exoribonuclease ExoN.
    Moeller NH; Shi K; Demir Ö; Belica C; Banerjee S; Yin L; Durfee C; Amaro RE; Aihara H
    Proc Natl Acad Sci U S A; 2022 Mar; 119(9):. PubMed ID: 35165203
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 46.