These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

167 related articles for article (PubMed ID: 2904702)

  • 1. Repair of the secretion defect in the Z form of alpha 1-antitrypsin by addition of a second mutation.
    Brantly M; Courtney M; Crystal RG
    Science; 1988 Dec; 242(4886):1700-2. PubMed ID: 2904702
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Molecular basis of the liver and lung disease associated with the alpha 1-antitrypsin deficiency allele Mmalton.
    Curiel DT; Holmes MD; Okayama H; Brantly ML; Vogelmeier C; Travis WD; Stier LE; Perks WH; Crystal RG
    J Biol Chem; 1989 Aug; 264(23):13938-45. PubMed ID: 2788166
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Serum alpha 1-antitrypsin deficiency associated with the common S-type (Glu264----Val) mutation results from intracellular degradation of alpha 1-antitrypsin prior to secretion.
    Curiel DT; Chytil A; Courtney M; Crystal RG
    J Biol Chem; 1989 Jun; 264(18):10477-86. PubMed ID: 2567291
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Molecular basis of alpha 1-antitrypsin deficiency and emphysema associated with the alpha 1-antitrypsin Mmineral springs allele.
    Curiel DT; Vogelmeier C; Hubbard RC; Stier LE; Crystal RG
    Mol Cell Biol; 1990 Jan; 10(1):47-56. PubMed ID: 1967187
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Disruption of the 290-342 salt bridge is not responsible for the secretory defect of the PiZ alpha 1-antitrypsin variant.
    Sifers RN; Hardick CP; Woo SL
    J Biol Chem; 1989 Feb; 264(5):2997-3001. PubMed ID: 2563374
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Alpha 1-antitrypsin Wbethesda: molecular basis of an unusual alpha 1-antitrypsin deficiency variant.
    Holmes MD; Brantly ML; Fells GA; Crystal RG
    Biochem Biophys Res Commun; 1990 Aug; 170(3):1013-20. PubMed ID: 2390072
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of a second mutation in the protein-coding sequence of the Z type alpha 1-antitrypsin gene.
    Nukiwa T; Satoh K; Brantly ML; Ogushi F; Fells GA; Courtney M; Crystal RG
    J Biol Chem; 1986 Dec; 261(34):15989-94. PubMed ID: 3491072
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Alpha 1-antitrypsin deficiency caused by the alpha 1-antitrypsin Nullmattawa gene. An insertion mutation rendering the alpha 1-antitrypsin gene incapable of producing alpha 1-antitrypsin.
    Curiel D; Brantly M; Curiel E; Stier L; Crystal RG
    J Clin Invest; 1989 Apr; 83(4):1144-52. PubMed ID: 2539391
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Z-type alpha 1-antitrypsin is less competent than M1-type alpha 1-antitrypsin as an inhibitor of neutrophil elastase.
    Ogushi F; Fells GA; Hubbard RC; Straus SD; Crystal RG
    J Clin Invest; 1987 Nov; 80(5):1366-74. PubMed ID: 3500183
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Alpha 1-antitrypsin nonsense mutation associated with a retained truncated protein and reduced mRNA.
    Lee J; Novoradovskaya N; Rundquist B; Redwine J; Saltini C; Brantly M
    Mol Genet Metab; 1998 Apr; 63(4):270-80. PubMed ID: 9635295
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Emphysema associated with complete absence of alpha 1- antitrypsin in serum and the homozygous inheritance [corrected] of a stop codon in an alpha 1-antitrypsin-coding exon.
    Satoh K; Nukiwa T; Brantly M; Garver RI; Hofker M; Courtney M; Crystal RG
    Am J Hum Genet; 1988 Jan; 42(1):77-83. PubMed ID: 3257351
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Ribonuclease A cleavage combined with the polymerase chain reaction for detection of the Z mutation of the alpha-1-antitrypsin gene.
    Abe T; Takahashi H; Holmes MD; Curiel DT; Crystal RG
    Am J Respir Cell Mol Biol; 1989 Oct; 1(4):329-34. PubMed ID: 2624766
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Molecular characterisation of the defective alpha 1-antitrypsin alleles PI Mwurzburg (Pro369Ser), Mheerlen (Pro369Leu), and Q0lisbon (Thr68Ile).
    Poller W; Merklein F; Schneider-Rasp S; Haack A; Fechner H; Wang H; Anagnostopoulos I; Weidinger S
    Eur J Hum Genet; 1999 Apr; 7(3):321-31. PubMed ID: 10234508
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Characterization of a human alpha 1-antitrypsin null allele involving aberrant mRNA splicing.
    Laubach VE; Ryan WJ; Brantly M
    Hum Mol Genet; 1993 Jul; 2(7):1001-5. PubMed ID: 8364536
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Evaluation of recombinant DNA-directed E.coli produced alpha 1-antitrypsin as an anti-neutrophil elastase for potential use as replacement therapy of alpha 1-antitrypsin deficiency.
    Straus SD; Fells GA; Wewers MD; Courtney M; Tessier LH; Tolstoshev P; Lecocq JP; Crystal RG
    Biochem Biophys Res Commun; 1985 Aug; 130(3):1177-84. PubMed ID: 3896239
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Disruption of the Lys-290--Glu-342 salt bridge in human alpha 1-antitrypsin does not prevent its synthesis and secretion.
    Foreman RC
    FEBS Lett; 1987 May; 216(1):79-82. PubMed ID: 2884131
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A novel SV40-based vector successfully transduces and expresses an alpha 1-antitrypsin ribozyme in a human hepatoma-derived cell line.
    Zern MA; Ozaki I; Duan L; Pomerantz R; Liu SL; Strayer DS
    Gene Ther; 1999 Jan; 6(1):114-20. PubMed ID: 10341883
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Alpha 1-antitrypsin Null(isola di procida): an alpha 1-antitrypsin deficiency allele caused by deletion of all alpha 1-antitrypsin coding exons.
    Takahashi H; Crystal RG
    Am J Hum Genet; 1990 Sep; 47(3):403-13. PubMed ID: 1975477
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Evaluation of tamoxifen as a therapy to augment alpha-1-antitrypsin concentrations in Z homozygous alpha-1-antitrypsin-deficient subjects.
    Wewers MD; Brantly ML; Casolaro MA; Crystal RG
    Am Rev Respir Dis; 1987 Feb; 135(2):401-2. PubMed ID: 3492949
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Biosynthesis, processing, and secretion of M and Z variant human alpha 1-antitrypsin.
    Verbanac KM; Heath EC
    J Biol Chem; 1986 Jul; 261(21):9979-89. PubMed ID: 3015914
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.