These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

126 related articles for article (PubMed ID: 29051386)

  • 1. Ets2 anchors the prometastatic function of mutant p53 in osteosarcoma.
    Liu DD; Kang Y
    Genes Dev; 2017 Sep; 31(18):1823-1824. PubMed ID: 29051386
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Integrative genome analysis of somatic p53 mutant osteosarcomas identifies Ets2-dependent regulation of small nucleolar RNAs by mutant p53 protein.
    Pourebrahim R; Zhang Y; Liu B; Gao R; Xiong S; Lin PP; McArthur MJ; Ostrowski MC; Lozano G
    Genes Dev; 2017 Sep; 31(18):1847-1857. PubMed ID: 29021240
    [No Abstract]   [Full Text] [Related]  

  • 3. Mutant p53 protects ETS2 from non-canonical COP1/DET1 dependent degradation.
    Carrero ZI; Kollareddy M; Chauhan KM; Ramakrishnan G; Martinez LA
    Oncotarget; 2016 Mar; 7(11):12554-67. PubMed ID: 26871468
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Differential Gain-of-Function Activity of Three p53 Hotspot Mutants In Vivo.
    Xiong S; Chachad D; Zhang Y; Gencel-Augusto J; Sirito M; Pant V; Yang P; Sun C; Chau G; Qi Y; Su X; Whitley EM; El-Naggar AK; Lozano G
    Cancer Res; 2022 May; 82(10):1926-1936. PubMed ID: 35320355
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mutant p53 gain of function can be at the root of dedifferentiation of human osteosarcoma MG63 cells into 3AB-OS cancer stem cells.
    Di Fiore R; Marcatti M; Drago-Ferrante R; D'Anneo A; Giuliano M; Carlisi D; De Blasio A; Querques F; Pastore L; Tesoriere G; Vento R
    Bone; 2014 Mar; 60():198-212. PubMed ID: 24373920
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Unique Transcriptional Profiles Underlie Osteosarcomagenesis Driven by Different p53 Mutants.
    Chachad D; Patel LR; Recio CV; Pourebrahim R; Whitley EM; Wang W; Su X; Xu A; Lee DF; Lozano G
    Cancer Res; 2023 Jul; 83(14):2297-2311. PubMed ID: 37205631
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mutant p53 promotes tumor progression and metastasis by the endoplasmic reticulum UDPase ENTPD5.
    Vogiatzi F; Brandt DT; Schneikert J; Fuchs J; Grikscheit K; Wanzel M; Pavlakis E; Charles JP; Timofeev O; Nist A; Mernberger M; Kantelhardt EJ; Siebolts U; Bartel F; Jacob R; Rath A; Moll R; Grosse R; Stiewe T
    Proc Natl Acad Sci U S A; 2016 Dec; 113(52):E8433-E8442. PubMed ID: 27956623
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutant p53 induces the GEF-H1 oncogene, a guanine nucleotide exchange factor-H1 for RhoA, resulting in accelerated cell proliferation in tumor cells.
    Mizuarai S; Yamanaka K; Kotani H
    Cancer Res; 2006 Jun; 66(12):6319-26. PubMed ID: 16778209
    [TBL] [Abstract][Full Text] [Related]  

  • 9. ONZIN Upregulation by Mutant p53 Contributes to Osteosarcoma Metastasis Through the CXCL5-MAPK Signaling Pathway.
    Zhang Y; Hu Q; Li G; Li L; Liang S; Zhang Y; Liu J; Fan Z; Li L; Zhou B; Ruan Y; Yang X; Chen S; Mu T; Wang G; Xiong S
    Cell Physiol Biochem; 2018; 48(3):1099-1111. PubMed ID: 30041188
    [TBL] [Abstract][Full Text] [Related]  

  • 10. p53 loss-of-heterozygosity is a necessary prerequisite for mutant p53 stabilization and gain-of-function in vivo.
    Alexandrova EM; Mirza SA; Xu S; Schulz-Heddergott R; Marchenko ND; Moll UM
    Cell Death Dis; 2017 Mar; 8(3):e2661. PubMed ID: 28277540
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pla2g16 phospholipase mediates gain-of-function activities of mutant p53.
    Xiong S; Tu H; Kollareddy M; Pant V; Li Q; Zhang Y; Jackson JG; Suh YA; Elizondo-Fraire AC; Yang P; Chau G; Tashakori M; Wasylishen AR; Ju Z; Solomon H; Rotter V; Liu B; El-Naggar AK; Donehower LA; Martinez LA; Lozano G
    Proc Natl Acad Sci U S A; 2014 Jul; 111(30):11145-50. PubMed ID: 25024203
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ETS1 and ETS2 in p53 regulation: spatial separation of ETS binding sites (EBS) modulate protein: DNA interaction.
    Venanzoni MC; Robinson LR; Hodge DR; Kola I; Seth A
    Oncogene; 1996 Mar; 12(6):1199-1204. PubMed ID: 8649821
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Gain-of-function mutant p53 in cancer progression and therapy.
    Zhang C; Liu J; Xu D; Zhang T; Hu W; Feng Z
    J Mol Cell Biol; 2020 Sep; 12(9):674-687. PubMed ID: 32722796
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Androgen-independent growth of LNCaP prostate cancer cells is mediated by gain-of-function mutant p53.
    Nesslinger NJ; Shi XB; deVere White RW
    Cancer Res; 2003 May; 63(9):2228-33. PubMed ID: 12727844
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Gain-of-function mutant p53 upregulates CXC chemokines and enhances cell migration.
    Yeudall WA; Vaughan CA; Miyazaki H; Ramamoorthy M; Choi MY; Chapman CG; Wang H; Black E; Bulysheva AA; Deb SP; Windle B; Deb S
    Carcinogenesis; 2012 Feb; 33(2):442-51. PubMed ID: 22114072
    [TBL] [Abstract][Full Text] [Related]  

  • 16. ETS2 overexpression in transgenic models and in Down syndrome predisposes to apoptosis via the p53 pathway.
    Wolvetang EJ; Wilson TJ; Sanij E; Busciglio J; Hatzistavrou T; Seth A; Hertzog PJ; Kola I
    Hum Mol Genet; 2003 Feb; 12(3):247-55. PubMed ID: 12554679
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Gain-of-function mutant p53 activates small GTPase Rac1 through SUMOylation to promote tumor progression.
    Yue X; Zhang C; Zhao Y; Liu J; Lin AW; Tan VM; Drake JM; Liu L; Boateng MN; Li J; Feng Z; Hu W
    Genes Dev; 2017 Aug; 31(16):1641-1654. PubMed ID: 28947497
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Activation of PTHrP-cAMP-CREB1 signaling following p53 loss is essential for osteosarcoma initiation and maintenance.
    Walia MK; Ho PM; Taylor S; Ng AJ; Gupte A; Chalk AM; Zannettino AC; Martin TJ; Walkley CR
    Elife; 2016 Apr; 5():. PubMed ID: 27070462
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Depletion of R270C Mutant p53 in Osteosarcoma Attenuates Cell Growth but Does Not Prevent Invasion and Metastasis In Vivo.
    Shimizu T; Sugihara E; Takeshima H; Nobusue H; Yamaguchi R; Yamaguchi-Iwai S; Fukuchi Y; Ushijima T; Muto A; Saya H
    Cells; 2022 Nov; 11(22):. PubMed ID: 36429043
    [TBL] [Abstract][Full Text] [Related]  

  • 20. ΔNp63 mediates cellular survival and metastasis in canine osteosarcoma.
    Cam M; Gardner HL; Roberts RD; Fenger JM; Guttridge DC; London CA; Cam H
    Oncotarget; 2016 Jul; 7(30):48533-48546. PubMed ID: 27391430
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.