These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

274 related articles for article (PubMed ID: 29051536)

  • 21. Synthesis and Evaluation of diaryl ether modulators of the leukotriene A
    Petruncio G; Lee KH; Girgis M; Shellnutt Z; Beaulac Z; Xiang J; Lee SH; Peng X; Burdick M; Noble SM; Shim YM; Paige M
    Eur J Med Chem; 2024 Jun; 272():116459. PubMed ID: 38704942
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Inhibition of leukotriene A4 hydrolase/aminopeptidase by captopril.
    Orning L; Krivi G; Bild G; Gierse J; Aykent S; Fitzpatrick FA
    J Biol Chem; 1991 Sep; 266(25):16507-11. PubMed ID: 1885582
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Anti-inflammatory activity of a potent, selective leukotriene A4 hydrolase inhibitor in comparison with the 5-lipoxygenase inhibitor zileuton.
    Rao NL; Dunford PJ; Xue X; Jiang X; Lundeen KA; Coles F; Riley JP; Williams KN; Grice CA; Edwards JP; Karlsson L; Fourie AM
    J Pharmacol Exp Ther; 2007 Jun; 321(3):1154-60. PubMed ID: 17371808
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Saccharomyces cerevisiae leukotriene A4 hydrolase: formation of leukotriene B4 and identification of catalytic residues.
    Kull F; Ohlson E; Lind B; Haeggström JZ
    Biochemistry; 2001 Oct; 40(42):12695-703. PubMed ID: 11601994
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Classification and QSAR models of leukotriene A4 hydrolase (LTA4H) inhibitors by machine learning methods.
    Qin R; Wang H; Yan A
    SAR QSAR Environ Res; 2021 May; 32(5):411-431. PubMed ID: 33896285
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Drug discovery strategies for novel leukotriene A4 hydrolase inhibitors.
    Röhn TA; Numao S; Otto H; Loesche C; Thoma G
    Expert Opin Drug Discov; 2021 Dec; 16(12):1483-1495. PubMed ID: 34191664
    [TBL] [Abstract][Full Text] [Related]  

  • 27. A remarkable activity of human leukotriene A4 hydrolase (LTA4H) toward unnatural amino acids.
    Byzia A; Haeggström JZ; Salvesen GS; Drag M
    Amino Acids; 2014 May; 46(5):1313-20. PubMed ID: 24573245
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Crystal structure of leukotriene A4 hydrolase in complex with kelatorphan, implications for design of zinc metallopeptidase inhibitors.
    Tholander F; Roques BP; Fournié-Zaluski MC; Thunnissen MM; Haeggström JZ
    FEBS Lett; 2010 Aug; 584(15):3446-51. PubMed ID: 20609366
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Discovery of LYS006, a Potent and Highly Selective Inhibitor of Leukotriene A
    Markert C; Thoma G; Srinivas H; Bollbuck B; Lüönd RM; Miltz W; Wälchli R; Wolf R; Hinrichs J; Bergsdorf C; Azzaoui K; Penno CA; Klein K; Wack N; Jäger P; Hasler F; Beerli C; Loetscher P; Dawson J; Wieczorek G; Numao S; Littlewood-Evans A; Röhn TA
    J Med Chem; 2021 Feb; 64(4):1889-1903. PubMed ID: 33592148
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Leukotriene A4 hydrolase: selective abrogation of leukotriene B4 formation by mutation of aspartic acid 375.
    Rudberg PC; Tholander F; Thunnissen MM; Samuelsson B; Haeggstrom JZ
    Proc Natl Acad Sci U S A; 2002 Apr; 99(7):4215-20. PubMed ID: 11917124
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Pharmacophore-based virtual screening and Bayesian model for the identification of potential human leukotriene A4 hydrolase inhibitors.
    Thangapandian S; John S; Sakkiah S; Lee KW
    Eur J Med Chem; 2011 May; 46(5):1593-603. PubMed ID: 21377770
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Structure-based dissection of the active site chemistry of leukotriene A4 hydrolase: implications for M1 aminopeptidases and inhibitor design.
    Tholander F; Muroya A; Roques BP; Fournié-Zaluski MC; Thunnissen MM; Haeggström JZ
    Chem Biol; 2008 Sep; 15(9):920-9. PubMed ID: 18804029
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Matrikines are key regulators in modulating the amplitude of lung inflammation in acute pulmonary infection.
    Akthar S; Patel DF; Beale RC; Peiró T; Xu X; Gaggar A; Jackson PL; Blalock JE; Lloyd CM; Snelgrove RJ
    Nat Commun; 2015 Sep; 6():8423. PubMed ID: 26400771
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Development of selective tight-binding inhibitors of leukotriene A4 hydrolase.
    Yuan W; Munoz B; Wong CH; Haeggström JZ; Wetterholm A; Samuelsson B
    J Med Chem; 1993 Jan; 36(2):211-20. PubMed ID: 8423594
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Substrate-dependent modulation of the leukotriene A
    Lee KH; Ali NF; Lee SH; Zhang Z; Burdick M; Beaulac ZJ; Petruncio G; Li L; Xiang J; Chung EM; Foreman KW; Noble SM; Shim YM; Paige M
    Sci Rep; 2022 Jun; 12(1):9443. PubMed ID: 35676292
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Molecular dynamics simulation study and hybrid pharmacophore model development in human LTA4H inhibitor design.
    Thangapandian S; John S; Arooj M; Lee KW
    PLoS One; 2012; 7(4):e34593. PubMed ID: 22496831
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Modulating the substrate specificity of LTA4H aminopeptidase by using chemical compounds and small-molecule-guided mutagenesis.
    Jiang X; Zhou L; Wu Y; Wei D; Sun C; Jia J; Liu Y; Lai L
    Chembiochem; 2010 May; 11(8):1120-8. PubMed ID: 20432426
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Aminopeptidase B is structurally related to leukotriene-A4 hydrolase but is not a bifunctional enzyme with epoxide hydrolase activity.
    Fukasawa KM; Fukasawa K; Harada M; Hirose J; Izumi T; Shimizu T
    Biochem J; 1999 May; 339 ( Pt 3)(Pt 3):497-502. PubMed ID: 10215585
    [TBL] [Abstract][Full Text] [Related]  

  • 39. The bifunctional enzyme leukotriene-A4 hydrolase is an arginine aminopeptidase of high efficiency and specificity.
    Orning L; Gierse JK; Fitzpatrick FA
    J Biol Chem; 1994 Apr; 269(15):11269-73. PubMed ID: 8157657
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Effect of Modifier Structure on the Activation of Leukotriene A
    Lee KH; Petruncio G; Shim A; Burdick M; Zhang Z; Shim YM; Noble SM; Paige M
    J Med Chem; 2019 Dec; 62(23):10605-10616. PubMed ID: 31751136
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 14.