These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

274 related articles for article (PubMed ID: 29051562)

  • 1. Motifs in the tau protein that control binding to microtubules and aggregation determine pathological effects.
    Lathuilière A; Valdés P; Papin S; Cacquevel M; Maclachlan C; Knott GW; Muhs A; Paganetti P; Schneider BL
    Sci Rep; 2017 Oct; 7(1):13556. PubMed ID: 29051562
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Phosphorylation that detaches tau protein from microtubules (Ser262, Ser214) also protects it against aggregation into Alzheimer paired helical filaments.
    Schneider A; Biernat J; von Bergen M; Mandelkow E; Mandelkow EM
    Biochemistry; 1999 Mar; 38(12):3549-58. PubMed ID: 10090741
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Tau missorting and spastin-induced microtubule disruption in neurodegeneration: Alzheimer Disease and Hereditary Spastic Paraplegia.
    Zempel H; Mandelkow EM
    Mol Neurodegener; 2015 Dec; 10():68. PubMed ID: 26691836
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Impaired tau-microtubule interactions are prevalent among pathogenic tau variants arising from missense mutations.
    Xia Y; Sorrentino ZA; Kim JD; Strang KH; Riffe CJ; Giasson BI
    J Biol Chem; 2019 Nov; 294(48):18488-18503. PubMed ID: 31653695
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural and functional implications of tau hyperphosphorylation: information from phosphorylation-mimicking mutated tau proteins.
    Eidenmüller J; Fath T; Hellwig A; Reed J; Sontag E; Brandt R
    Biochemistry; 2000 Oct; 39(43):13166-75. PubMed ID: 11052669
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A unique tau conformation generated by an acetylation-mimic substitution modulates P301S-dependent tau pathology and hyperphosphorylation.
    Ajit D; Trzeciakiewicz H; Tseng JH; Wander CM; Chen Y; Ajit A; King DP; Cohen TJ
    J Biol Chem; 2019 Nov; 294(45):16698-16711. PubMed ID: 31543505
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The GABAergic septohippocampal connection is impaired in a mouse model of tauopathy.
    Soler H; Dorca-Arévalo J; González M; Rubio SE; Ávila J; Soriano E; Pascual M
    Neurobiol Aging; 2017 Jan; 49():40-51. PubMed ID: 27743524
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Tau pathology in Alzheimer disease and other tauopathies.
    Iqbal K; Alonso Adel C; Chen S; Chohan MO; El-Akkad E; Gong CX; Khatoon S; Li B; Liu F; Rahman A; Tanimukai H; Grundke-Iqbal I
    Biochim Biophys Acta; 2005 Jan; 1739(2-3):198-210. PubMed ID: 15615638
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A novel transgenic mouse expressing double mutant tau driven by its natural promoter exhibits tauopathy characteristics.
    Rosenmann H; Grigoriadis N; Eldar-Levy H; Avital A; Rozenstein L; Touloumi O; Behar L; Ben-Hur T; Avraham Y; Berry E; Segal M; Ginzburg I; Abramsky O
    Exp Neurol; 2008 Jul; 212(1):71-84. PubMed ID: 18490011
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Axodendritic sorting and pathological missorting of Tau are isoform-specific and determined by axon initial segment architecture.
    Zempel H; Dennissen FJA; Kumar Y; Luedtke J; Biernat J; Mandelkow EM; Mandelkow E
    J Biol Chem; 2017 Jul; 292(29):12192-12207. PubMed ID: 28536263
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mutant (R406W) human tau is hyperphosphorylated and does not efficiently bind microtubules in a neuronal cortical cell model.
    Krishnamurthy PK; Johnson GV
    J Biol Chem; 2004 Feb; 279(9):7893-900. PubMed ID: 14660557
    [TBL] [Abstract][Full Text] [Related]  

  • 12. FTDP-17 mutations in tau transgenic mice provoke lysosomal abnormalities and Tau filaments in forebrain.
    Lim F; Hernández F; Lucas JJ; Gómez-Ramos P; Morán MA; Avila J
    Mol Cell Neurosci; 2001 Dec; 18(6):702-14. PubMed ID: 11749044
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Regulation of mitochondrial transport and inter-microtubule spacing by tau phosphorylation at the sites hyperphosphorylated in Alzheimer's disease.
    Shahpasand K; Uemura I; Saito T; Asano T; Hata K; Shibata K; Toyoshima Y; Hasegawa M; Hisanaga S
    J Neurosci; 2012 Feb; 32(7):2430-41. PubMed ID: 22396417
    [TBL] [Abstract][Full Text] [Related]  

  • 14. GFP-Mutant Human Tau Transgenic Mice Develop Tauopathy Following CNS Injections of Alzheimer's Brain-Derived Pathological Tau or Synthetic Mutant Human Tau Fibrils.
    Gibbons GS; Banks RA; Kim B; Xu H; Changolkar L; Leight SN; Riddle DM; Li C; Gathagan RJ; Brown HJ; Zhang B; Trojanowski JQ; Lee VM
    J Neurosci; 2017 Nov; 37(47):11485-11494. PubMed ID: 28986461
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Conformational changes specific for pseudophosphorylation at serine 262 selectively impair binding of tau to microtubules.
    Fischer D; Mukrasch MD; Biernat J; Bibow S; Blackledge M; Griesinger C; Mandelkow E; Zweckstetter M
    Biochemistry; 2009 Oct; 48(42):10047-55. PubMed ID: 19769346
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A brain-penetrant triazolopyrimidine enhances microtubule-stability, reduces axonal dysfunction and decreases tau pathology in a mouse tauopathy model.
    Zhang B; Yao Y; Cornec AS; Oukoloff K; James MJ; Koivula P; Trojanowski JQ; Smith AB; Lee VM; Ballatore C; Brunden KR
    Mol Neurodegener; 2018 Nov; 13(1):59. PubMed ID: 30404654
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Role of microtubule-associated protein tau phosphorylation in Alzheimer's disease.
    Ma RH; Zhang Y; Hong XY; Zhang JF; Wang JZ; Liu GP
    J Huazhong Univ Sci Technolog Med Sci; 2017 Jun; 37(3):307-312. PubMed ID: 28585125
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structure, microtubule interactions, and paired helical filament aggregation by tau mutants of frontotemporal dementias.
    Barghorn S; Zheng-Fischhöfer Q; Ackmann M; Biernat J; von Bergen M; Mandelkow EM; Mandelkow E
    Biochemistry; 2000 Sep; 39(38):11714-21. PubMed ID: 10995239
    [TBL] [Abstract][Full Text] [Related]  

  • 19. SUMOylation at K340 inhibits tau degradation through deregulating its phosphorylation and ubiquitination.
    Luo HB; Xia YY; Shu XJ; Liu ZC; Feng Y; Liu XH; Yu G; Yin G; Xiong YS; Zeng K; Jiang J; Ye K; Wang XC; Wang JZ
    Proc Natl Acad Sci U S A; 2014 Nov; 111(46):16586-91. PubMed ID: 25378699
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Alpha1-antichymotrypsin, an inflammatory protein overexpressed in Alzheimer's disease brain, induces tau phosphorylation in neurons.
    Padmanabhan J; Levy M; Dickson DW; Potter H
    Brain; 2006 Nov; 129(Pt 11):3020-34. PubMed ID: 16987932
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.