BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

844 related articles for article (PubMed ID: 29056363)

  • 1. Pramipexole reduces soluble mutant huntingtin and protects striatal neurons through dopamine D3 receptors in a genetic model of Huntington's disease.
    Luis-Ravelo D; Estévez-Silva H; Barroso-Chinea P; Afonso-Oramas D; Salas-Hernández J; Rodríguez-Núñez J; Acevedo-Arozena A; Marcellino D; González-Hernández T
    Exp Neurol; 2018 Jan; 299(Pt A):137-147. PubMed ID: 29056363
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Effects of Exogenous NUB1 Expression in the Striatum of HDQ175/Q7 Mice.
    Vodicka P; Chase K; Iuliano M; Valentine DT; Sapp E; Lu B; Kegel-Gleason KB; Sena-Esteves M; Aronin N; DiFiglia M
    J Huntingtons Dis; 2016 Jun; 5(2):163-74. PubMed ID: 27314618
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Coupling of D2R Short but not D2R Long receptor isoform to the Rho/ROCK signaling pathway renders striatal neurons vulnerable to mutant huntingtin.
    Galan-Rodriguez B; Martin E; Brouillet E; Déglon N; Betuing S; Caboche J
    Eur J Neurosci; 2017 Jan; 45(1):198-206. PubMed ID: 27717053
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Activation of NPY-Y2 receptors ameliorates disease pathology in the R6/2 mouse and PC12 cell models of Huntington's disease.
    Fatoba O; Kloster E; Reick C; Saft C; Gold R; Epplen JT; Arning L; Ellrichmann G
    Exp Neurol; 2018 Apr; 302():112-128. PubMed ID: 29309751
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Nemo-like kinase reduces mutant huntingtin levels and mitigates Huntington's disease.
    Jiang M; Zhang X; Liu H; LeBron J; Alexandris A; Peng Q; Gu H; Yang F; Li Y; Wang R; Hou Z; Arbez N; Ren Q; Dong JL; Whela E; Wang R; Ratovitski T; Troncoso JC; Mori S; Ross CA; Lim J; Duan W
    Hum Mol Genet; 2020 May; 29(8):1340-1352. PubMed ID: 32242231
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Gossypol, a novel modulator of VCP, induces autophagic degradation of mutant huntingtin by promoting the formation of VCP/p97-LC3-mHTT complex.
    Li XJ; Zhang YY; Fu YH; Zhang H; Li HX; Li QF; Li HL; Tan RK; Jiang CX; Jiang W; Li ZX; Luo C; Lu BX; Dang YJ
    Acta Pharmacol Sin; 2021 Oct; 42(10):1556-1566. PubMed ID: 33495516
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Deletion of SUMO1 attenuates behavioral and anatomical deficits by regulating autophagic activities in Huntington disease.
    Ramírez-Jarquín UN; Sharma M; Zhou W; Shahani N; Subramaniam S
    Proc Natl Acad Sci U S A; 2022 Feb; 119(5):. PubMed ID: 35086928
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Autophagy Activation by Transcription Factor EB (TFEB) in Striatum of HDQ175/Q7 Mice.
    Vodicka P; Chase K; Iuliano M; Tousley A; Valentine DT; Sapp E; Kegel-Gleason KB; Sena-Esteves M; Aronin N; DiFiglia M
    J Huntingtons Dis; 2016 Oct; 5(3):249-260. PubMed ID: 27689619
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Compartment-Dependent Degradation of Mutant Huntingtin Accounts for Its Preferential Accumulation in Neuronal Processes.
    Zhao T; Hong Y; Li S; Li XJ
    J Neurosci; 2016 Aug; 36(32):8317-28. PubMed ID: 27511006
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Neuroprotection of pramipexole in UPS impairment induced animal model of Parkinson's disease.
    Li C; Guo Y; Xie W; Li X; Janokovic J; Le W
    Neurochem Res; 2010 Oct; 35(10):1546-56. PubMed ID: 20635141
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Gedunin Degrades Aggregates of Mutant Huntingtin Protein and Intranuclear Inclusions via the Proteasomal Pathway in Neurons and Fibroblasts from Patients with Huntington's Disease.
    Yang W; Xie J; Qiang Q; Li L; Lin X; Ren Y; Ren W; Liu Q; Zhou G; Wei W; Saiyin H; Ma L
    Neurosci Bull; 2019 Dec; 35(6):1024-1034. PubMed ID: 31432317
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of GSK-3 ameliorates the pathogenesis of Huntington's disease.
    Rippin I; Bonder K; Joseph S; Sarsor A; Vaks L; Eldar-Finkelman H
    Neurobiol Dis; 2021 Jul; 154():105336. PubMed ID: 33753290
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Prolonged treatment with pramipexole promotes physical interaction of striatal dopamine D3 autoreceptors with dopamine transporters to reduce dopamine uptake.
    Castro-Hernández J; Afonso-Oramas D; Cruz-Muros I; Salas-Hernández J; Barroso-Chinea P; Moratalla R; Millan MJ; González-Hernández T
    Neurobiol Dis; 2015 Feb; 74():325-35. PubMed ID: 25511804
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Serine 421 regulates mutant huntingtin toxicity and clearance in mice.
    Kratter IH; Zahed H; Lau A; Tsvetkov AS; Daub AC; Weiberth KF; Gu X; Saudou F; Humbert S; Yang XW; Osmand A; Steffan JS; Masliah E; Finkbeiner S
    J Clin Invest; 2016 Sep; 126(9):3585-97. PubMed ID: 27525439
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Trehalose rescues glial cell dysfunction in striatal cultures from HD R6/1 mice at early postnatal development.
    Perucho J; Gómez A; Muñoz MP; de Yébenes JG; Mena MÁ; Casarejos MJ
    Mol Cell Neurosci; 2016 Jul; 74():128-45. PubMed ID: 27236019
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Intrastriatal rAAV-mediated delivery of anti-huntingtin shRNAs induces partial reversal of disease progression in R6/1 Huntington's disease transgenic mice.
    Rodriguez-Lebron E; Denovan-Wright EM; Nash K; Lewin AS; Mandel RJ
    Mol Ther; 2005 Oct; 12(4):618-33. PubMed ID: 16019264
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Azadiradione Restores Protein Quality Control and Ameliorates the Disease Pathogenesis in a Mouse Model of Huntington's Disease.
    Singh BK; Vatsa N; Nelson VK; Kumar V; Kumar SS; Mandal SC; Pal M; Jana NR
    Mol Neurobiol; 2018 Aug; 55(8):6337-6346. PubMed ID: 29294248
    [TBL] [Abstract][Full Text] [Related]  

  • 18. In vivo expression of polyglutamine-expanded huntingtin by mouse striatal astrocytes impairs glutamate transport: a correlation with Huntington's disease subjects.
    Faideau M; Kim J; Cormier K; Gilmore R; Welch M; Auregan G; Dufour N; Guillermier M; Brouillet E; Hantraye P; Déglon N; Ferrante RJ; Bonvento G
    Hum Mol Genet; 2010 Aug; 19(15):3053-67. PubMed ID: 20494921
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Wild-type huntingtin ameliorates striatal neuronal atrophy but does not prevent other abnormalities in the YAC128 mouse model of Huntington disease.
    Van Raamsdonk JM; Pearson J; Murphy Z; Hayden MR; Leavitt BR
    BMC Neurosci; 2006 Dec; 7():80. PubMed ID: 17147801
    [TBL] [Abstract][Full Text] [Related]  

  • 20. TRiC subunits enhance BDNF axonal transport and rescue striatal atrophy in Huntington's disease.
    Zhao X; Chen XQ; Han E; Hu Y; Paik P; Ding Z; Overman J; Lau AL; Shahmoradian SH; Chiu W; Thompson LM; Wu C; Mobley WC
    Proc Natl Acad Sci U S A; 2016 Sep; 113(38):E5655-64. PubMed ID: 27601642
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 43.