BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

447 related articles for article (PubMed ID: 29061131)

  • 1. Proguanil and cycloguanil are organic cation transporter and multidrug and toxin extrusion substrates.
    van der Velden M; Bilos A; van den Heuvel JJMW; Rijpma SR; Hurkmans EGE; Sauerwein RW; Russel FGM; Koenderink JB
    Malar J; 2017 Oct; 16(1):422. PubMed ID: 29061131
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The Nonmetabolized β-Blocker Nadolol Is a Substrate of OCT1, OCT2, MATE1, MATE2-K, and P-Glycoprotein, but Not of OATP1B1 and OATP1B3.
    Misaka S; Knop J; Singer K; Hoier E; Keiser M; Müller F; Glaeser H; König J; Fromm MF
    Mol Pharm; 2016 Feb; 13(2):512-9. PubMed ID: 26702643
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Interplay of the Organic Cation Transporters OCT1 and OCT2 with the Apically Localized Export Protein MATE1 for the Polarized Transport of Trospium.
    Deutsch B; Neumeister C; Schwantes U; Fromm MF; König J
    Mol Pharm; 2019 Feb; 16(2):510-517. PubMed ID: 30656943
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Role of organic cation transporter OCT2 and multidrug and toxin extrusion proteins MATE1 and MATE2-K for transport and drug interactions of the antiviral lamivudine.
    Müller F; König J; Hoier E; Mandery K; Fromm MF
    Biochem Pharmacol; 2013 Sep; 86(6):808-15. PubMed ID: 23876341
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Elucidation of
    Miyake T; Mizuno T; Takehara I; Mochizuki T; Kimura M; Matsuki S; Irie S; Watanabe N; Kato Y; Ieiri I; Maeda K; Ando O; Kusuhara H
    Drug Metab Dispos; 2019 Nov; 47(11):1270-1280. PubMed ID: 31511257
    [TBL] [Abstract][Full Text] [Related]  

  • 6. OCT1 Deficiency Affects Hepatocellular Concentrations and Pharmacokinetics of Cycloguanil, the Active Metabolite of the Antimalarial Drug Proguanil.
    Matthaei J; Seitz T; Jensen O; Tann A; Prukop T; Tadjerpisheh S; Brockmöller J; Tzvetkov MV
    Clin Pharmacol Ther; 2019 Jan; 105(1):190-200. PubMed ID: 29882324
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Clinical Aspects of Drug-Drug Interaction and Drug Nephrotoxicity at Renal Organic Cation Transporters 2 (OCT2) and Multidrug and Toxin Exclusion 1, and 2-K (MATE1/MATE2-K).
    Saad AAA; Zhang F; Mohammed EAH; Wu X
    Biol Pharm Bull; 2022; 45(4):382-393. PubMed ID: 35370262
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Fampridine is a Substrate and Inhibitor of Human OCT2, but not of Human MATE1, or MATE2K.
    Xiao G; Rowbottom C; Boiselle C; Gan LS
    Pharm Res; 2018 Jun; 35(8):159. PubMed ID: 29915999
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of OCT2, MATE1 and MATE2-K as a possible mechanism of drug interaction between pazopanib and cisplatin.
    Sauzay C; White-Koning M; Hennebelle I; Deluche T; Delmas C; Imbs DC; Chatelut E; Thomas F
    Pharmacol Res; 2016 Aug; 110():89-95. PubMed ID: 27178732
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Moxifloxacin Is a Potent In Vitro Inhibitor of OCT- and MATE-Mediated Transport of Metformin and Ethambutol.
    Te Brake LH; van den Heuvel JJ; Buaben AO; van Crevel R; Bilos A; Russel FG; Aarnoutse RE; Koenderink JB
    Antimicrob Agents Chemother; 2016 Dec; 60(12):7105-7114. PubMed ID: 27645247
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibitory Effects of Green Tea and (-)-Epigallocatechin Gallate on Transport by OATP1B1, OATP1B3, OCT1, OCT2, MATE1, MATE2-K and P-Glycoprotein.
    Knop J; Misaka S; Singer K; Hoier E; Müller F; Glaeser H; König J; Fromm MF
    PLoS One; 2015; 10(10):e0139370. PubMed ID: 26426900
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Double-transfected MDCK cells expressing human OCT1/MATE1 or OCT2/MATE1: determinants of uptake and transcellular translocation of organic cations.
    König J; Zolk O; Singer K; Hoffmann C; Fromm MF
    Br J Pharmacol; 2011 Jun; 163(3):546-55. PubMed ID: 20883471
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mechanistic in vitro studies confirm that inhibition of the renal apical efflux transporter multidrug and toxin extrusion (MATE) 1, and not altered absorption, underlies the increased metformin exposure observed in clinical interactions with cimetidine, trimethoprim or pyrimethamine.
    Elsby R; Chidlaw S; Outteridge S; Pickering S; Radcliffe A; Sullivan R; Jones H; Butler P
    Pharmacol Res Perspect; 2017 Oct; 5(5):. PubMed ID: 28971610
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A drug-drug interaction study to evaluate the impact of peficitinib on OCT1- and MATE1-mediated transport of metformin in healthy volunteers.
    Shibata M; Toyoshima J; Kaneko Y; Oda K; Nishimura T
    Eur J Clin Pharmacol; 2020 Aug; 76(8):1135-1141. PubMed ID: 32472157
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Contribution of MATE1 to Renal Secretion of the NMDA Receptor Antagonist Memantine.
    Müller F; Weitz D; Derdau V; Sandvoss M; Mertsch K; König J; Fromm MF
    Mol Pharm; 2017 Sep; 14(9):2991-2998. PubMed ID: 28708400
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Renal Excretion of Dabigatran: The Potential Role of Multidrug and Toxin Extrusion (MATE) Proteins.
    Shen H; Yao M; Sinz M; Marathe P; Rodrigues AD; Zhu M
    Mol Pharm; 2019 Sep; 16(9):4065-4076. PubMed ID: 31335150
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Imatinib Uptake into Cells is Not Mediated by Organic Cation Transporters OCT1, OCT2, or OCT3, But is Influenced by Extracellular pH.
    Blanc Mettral J; Faller N; Cruchon S; Sottas L; Buclin T; Schild L; Choong E; Nahimana A; Decosterd LA
    Drug Metab Lett; 2019; 13(2):102-110. PubMed ID: 30734690
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Irinotecan Alters the Disposition of Morphine Via Inhibition of Organic Cation Transporter 1 (OCT1) and 2 (OCT2).
    Zhu P; Ye Z; Guo D; Xiong Z; Huang S; Guo J; Zhang W; Polli JE; Zhou H; Li Q; Shu Y
    Pharm Res; 2018 Oct; 35(12):243. PubMed ID: 30361780
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Characterization of cytochrome P450 (CYP) 2D6 drugs as substrates of human organic cation transporters and multidrug and toxin extrusion proteins.
    Neul C; Hofmann U; Schaeffeler E; Winter S; Klein K; Giacomini KM; Eichelbaum M; Schwab M; Nies AT
    Br J Pharmacol; 2021 Mar; 178(6):1459-1474. PubMed ID: 33434947
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cationic Compounds with SARS-CoV-2 Antiviral Activity and Their Interaction with Organic Cation Transporter/Multidrug and Toxin Extruder Secretory Transporters.
    Martinez-Guerrero L; Zhang X; Zorn KM; Ekins S; Wright SH
    J Pharmacol Exp Ther; 2021 Oct; 379(1):96-107. PubMed ID: 34253645
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.