BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

279 related articles for article (PubMed ID: 29063676)

  • 21. A histone deacetylase inhibitor LBH589 downregulates XIAP in mesothelioma cell lines which is likely responsible for increased apoptosis with TRAIL.
    Symanowski J; Vogelzang N; Zawel L; Atadja P; Pass H; Sharma S
    J Thorac Oncol; 2009 Feb; 4(2):149-60. PubMed ID: 19179889
    [TBL] [Abstract][Full Text] [Related]  

  • 22. TRAIL-induced apoptosis is preferentially mediated via TRAIL receptor 1 in pancreatic carcinoma cells and profoundly enhanced by XIAP inhibitors.
    Stadel D; Mohr A; Ref C; MacFarlane M; Zhou S; Humphreys R; Bachem M; Cohen G; Möller P; Zwacka RM; Debatin KM; Fulda S
    Clin Cancer Res; 2010 Dec; 16(23):5734-49. PubMed ID: 20940278
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Gefitinib reverses TRAIL resistance in human bladder cancer cell lines via inhibition of AKT-mediated X-linked inhibitor of apoptosis protein expression.
    Shrader M; Pino MS; Lashinger L; Bar-Eli M; Adam L; Dinney CP; McConkey DJ
    Cancer Res; 2007 Feb; 67(4):1430-5. PubMed ID: 17308080
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Smac mimetic Birinapant induces apoptosis and enhances TRAIL potency in inflammatory breast cancer cells in an IAP-dependent and TNF-α-independent mechanism.
    Allensworth JL; Sauer SJ; Lyerly HK; Morse MA; Devi GR
    Breast Cancer Res Treat; 2013 Jan; 137(2):359-71. PubMed ID: 23225169
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Bim plays a crucial role in synergistic induction of apoptosis by the histone deacetylase inhibitor SBHA and TRAIL in melanoma cells.
    Gillespie S; Borrow J; Zhang XD; Hersey P
    Apoptosis; 2006 Dec; 11(12):2251-65. PubMed ID: 17051334
    [TBL] [Abstract][Full Text] [Related]  

  • 26. The multikinase inhibitor sorafenib potentiates TRAIL lethality in human leukemia cells in association with Mcl-1 and cFLIPL down-regulation.
    Rosato RR; Almenara JA; Coe S; Grant S
    Cancer Res; 2007 Oct; 67(19):9490-500. PubMed ID: 17909059
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Preclinical characterization of AEG35156/GEM 640, a second-generation antisense oligonucleotide targeting X-linked inhibitor of apoptosis.
    LaCasse EC; Cherton-Horvat GG; Hewitt KE; Jerome LJ; Morris SJ; Kandimalla ER; Yu D; Wang H; Wang W; Zhang R; Agrawal S; Gillard JW; Durkin JP
    Clin Cancer Res; 2006 Sep; 12(17):5231-41. PubMed ID: 16951243
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Antitumor activity of bortezomib alone and in combination with TRAIL in human acute myeloid leukemia.
    Conticello C; Adamo L; Vicari L; Giuffrida R; Iannolo G; Anastasi G; Caruso L; Moschetti G; Cupri A; Palumbo GA; Gulisano M; De Maria R; Giustolisi R; Di Raimondo F
    Acta Haematol; 2008; 120(1):19-30. PubMed ID: 18716397
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Next-generation hypomethylating agent SGI-110 primes acute myeloid leukemia cells to IAP antagonist by activating extrinsic and intrinsic apoptosis pathways.
    Dittmann J; Haydn T; Metzger P; Ward GA; Boerries M; Vogler M; Fulda S
    Cell Death Differ; 2020 Jun; 27(6):1878-1895. PubMed ID: 31831875
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Small molecule XIAP inhibitors cooperate with TRAIL to induce apoptosis in childhood acute leukemia cells and overcome Bcl-2-mediated resistance.
    Fakler M; Loeder S; Vogler M; Schneider K; Jeremias I; Debatin KM; Fulda S
    Blood; 2009 Feb; 113(8):1710-22. PubMed ID: 19036706
    [TBL] [Abstract][Full Text] [Related]  

  • 31. The simultaneous inhibition of the mTOR and MAPK pathways with Gnetin-C induces apoptosis in acute myeloid leukemia.
    Espinoza JL; Elbadry MI; Taniwaki M; Harada K; Trung LQ; Nakagawa N; Takami A; Ishiyama K; Yamauchi T; Takenaka K; Nakao S
    Cancer Lett; 2017 Aug; 400():127-136. PubMed ID: 28456658
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Anti-CD33-antibodies labelled with the alpha-emitter Bismuth-213 kill CD33-positive acute myeloid leukaemia cells specifically by activation of caspases and break radio- and chemoresistance by inhibition of the anti-apoptotic proteins X-linked inhibitor of apoptosis protein and B-cell lymphoma-extra large.
    Friesen C; Roscher M; Hormann I; Leib O; Marx S; Moreno J; Miltner E
    Eur J Cancer; 2013 Jul; 49(11):2542-54. PubMed ID: 23684782
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Protein kinase C inhibition and x-linked inhibitor of apoptosis protein degradation contribute to the sensitization effect of luteolin on tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in cancer cells.
    Shi RX; Ong CN; Shen HM
    Cancer Res; 2005 Sep; 65(17):7815-23. PubMed ID: 16140950
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Targeting PDK1 with dichloroacetophenone to inhibit acute myeloid leukemia (AML) cell growth.
    Qin L; Tian Y; Yu Z; Shi D; Wang J; Zhang C; Peng R; Chen X; Liu C; Chen Y; Huang W; Deng W
    Oncotarget; 2016 Jan; 7(2):1395-407. PubMed ID: 26593251
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Curcumin augments therapeutic efficacy of TRAIL-based immunotoxins in leukemia.
    Surapally S; Jayaprakasam M; Verma RS
    Pharmacol Rep; 2020 Aug; 72(4):1032-1046. PubMed ID: 32141025
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Targeting AML through DR4 with a novel variant of rhTRAIL.
    Szegezdi E; Reis CR; van der Sloot AM; Natoni A; O'Reilly A; Reeve J; Cool RH; O'Dwyer M; Knapper S; Serrano L; Quax WJ; Samali A
    J Cell Mol Med; 2011 Oct; 15(10):2216-31. PubMed ID: 21070598
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Antitumor action of CDK inhibitor LS-007 as a single agent and in combination with ABT-199 against human acute leukemia cells.
    Xie S; Jiang H; Zhai XW; Wei F; Wang SD; Ding J; Chen Y
    Acta Pharmacol Sin; 2016 Nov; 37(11):1481-1489. PubMed ID: 27569395
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Caspase-3 cleaves XIAP in a positive feedback loop to sensitize melanoma cells to TRAIL-induced apoptosis.
    Hörnle M; Peters N; Thayaparasingham B; Vörsmann H; Kashkar H; Kulms D
    Oncogene; 2011 Feb; 30(5):575-87. PubMed ID: 20856198
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Quercetin sensitizes human myeloid leukemia KG-1 cells against TRAIL-induced apoptosis.
    Naimi A; Entezari A; Hagh MF; Hassanzadeh A; Saraei R; Solali S
    J Cell Physiol; 2019 Aug; 234(8):13233-13241. PubMed ID: 30589076
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Histone deacetylase inhibitors strongly sensitise neuroblastoma cells to TRAIL-induced apoptosis by a caspases-dependent increase of the pro- to anti-apoptotic proteins ratio.
    Mühlethaler-Mottet A; Flahaut M; Bourloud KB; Auderset K; Meier R; Joseph JM; Gross N
    BMC Cancer; 2006 Aug; 6():214. PubMed ID: 16930472
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 14.