BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

155 related articles for article (PubMed ID: 29063699)

  • 21. Case report of a rare purine synthesis disorder due to 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase (AICAR) deficiency.
    Joy P; Madhuri V; Palocaren T; Das S; Susan Cleave Abraham S; Korula S; Koshy B; Jose J; Chandran M; Danda S
    Brain Dev; 2022 Oct; 44(9):645-649. PubMed ID: 35637059
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Impact of genetic variants of ATP binding cassette B1, AICAR transformylase/IMP cyclohydrolase, folyl-polyglutamatesynthetase, and methylenetetrahydrofolatereductase on methotrexate toxicity.
    Sala-Icardo L; Lamana A; Ortiz AM; García Lorenzo E; Moreno Fresneda P; García-Vicuña R; González-Álvaro I
    Reumatol Clin; 2017; 13(6):318-325. PubMed ID: 27751863
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Analysis of substrate binding in individual active sites of bifunctional human ATIC.
    Witkowska D; Cox HL; Hall TC; Wildsmith GC; Machin DC; Webb ME
    Biochim Biophys Acta Proteins Proteom; 2018 Feb; 1866(2):254-263. PubMed ID: 29042184
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Associations of common polymorphisms in the thymidylate synthase, reduced folate carrier and 5-aminoimidazole-4-carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase genes with folate and homocysteine levels and venous thrombosis risk.
    Gellekink H; Blom HJ; den Heijer M
    Clin Chem Lab Med; 2007; 45(4):471-6. PubMed ID: 17439323
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Bifunctional enzyme ATIC promotes propagation of hepatocellular carcinoma by regulating AMPK-mTOR-S6 K1 signaling.
    Li M; Jin C; Xu M; Zhou L; Li D; Yin Y
    Cell Commun Signal; 2017 Dec; 15(1):52. PubMed ID: 29246230
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Identification of ATIC as a Novel Target for Chemoradiosensitization.
    Liu X; Paila UD; Teraoka SN; Wright JA; Huang X; Quinlan AR; Gatti RA; Concannon P
    Int J Radiat Oncol Biol Phys; 2018 Jan; 100(1):162-173. PubMed ID: 29029884
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Structure and functional relationships in human pur H.
    Beardsley GP; Rayl EA; Gunn K; Moroson BA; Seow H; Anderson KS; Vergis J; Fleming K; Worland S; Condon B; Davies J
    Adv Exp Med Biol; 1998; 431():221-6. PubMed ID: 9598063
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Crystal structure of AICAR transformylase IMP cyclohydrolase (TM1249) from Thermotoga maritima at 1.88 A resolution.
    Axelrod HL; McMullan D; Krishna SS; Miller MD; Elsliger MA; Abdubek P; Ambing E; Astakhova T; Carlton D; Chiu HJ; Clayton T; Duan L; Feuerhelm J; Grzechnik SK; Hale J; Han GW; Haugen J; Jaroszewski L; Jin KK; Klock HE; Knuth MW; Koesema E; Morse AT; Nigoghossian E; Okach L; Oommachen S; Paulsen J; Quijano K; Reyes R; Rife CL; van den Bedem H; Weekes D; White A; Wolf G; Xu Q; Hodgson KO; Wooley J; Deacon AM; Godzik A; Lesley SA; Wilson IA
    Proteins; 2008 May; 71(2):1042-9. PubMed ID: 18260100
    [No Abstract]   [Full Text] [Related]  

  • 29. 5-Amino-4-Imidazolecarboxamide Ribonucleotide Transformylase/IMP Cyclohydrolase Polymorphisms Affect the Susceptibility to Multiple Myeloma.
    Wang Y; Ling Z; Hu Z; Gui Y; Huang C; Yao Y; Li R
    Lab Med; 2022 Sep; 53(5):465-474. PubMed ID: 35397004
    [TBL] [Abstract][Full Text] [Related]  

  • 30. AICA-ribosiduria due to ATIC deficiency: Delineation of the phenotype with three novel cases, and long-term update on the first case.
    Ramond F; Rio M; Héron B; Imbard A; Marie S; Billiemaz K; Denommé-Pichon AS; Kuentz P; Ceballos I; Piraud M; Vincent MF; Touraine R
    J Inherit Metab Dis; 2020 Nov; 43(6):1254-1264. PubMed ID: 32557644
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Virtual screening of human 5-aminoimidazole-4-carboxamide ribonucleotide transformylase against the NCI diversity set by use of AutoDock to identify novel nonfolate inhibitors.
    Li C; Xu L; Wolan DW; Wilson IA; Olson AJ
    J Med Chem; 2004 Dec; 47(27):6681-90. PubMed ID: 15615517
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Targeting tumour proliferation with a small-molecule inhibitor of AICAR transformylase homodimerization.
    Spurr IB; Birts CN; Cuda F; Benkovic SJ; Blaydes JP; Tavassoli A
    Chembiochem; 2012 Jul; 13(11):1628-34. PubMed ID: 22764122
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Characterization of two 5-aminoimidazole-4-carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase isozymes from Saccharomyces cerevisiae.
    Tibbetts AS; Appling DR
    J Biol Chem; 2000 Jul; 275(27):20920-7. PubMed ID: 10877846
    [TBL] [Abstract][Full Text] [Related]  

  • 34. 5-Aminoimidazole-4-carboxamide ribotide transformylase-IMP cyclohydrolase from human CCRF-CEM leukemia cells: purification, pH dependence, and inhibitors.
    Szabados E; Hindmarsh EJ; Phillips L; Duggleby RG; Christopherson RI
    Biochemistry; 1994 Nov; 33(47):14237-45. PubMed ID: 7947835
    [TBL] [Abstract][Full Text] [Related]  

  • 35. The last enzyme of the de novo purine synthesis pathway 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (ATIC) plays a central role in insulin signaling and the Golgi/endosomes protein network.
    Boutchueng-Djidjou M; Collard-Simard G; Fortier S; Hébert SS; Kelly I; Landry CR; Faure RL
    Mol Cell Proteomics; 2015 Apr; 14(4):1079-92. PubMed ID: 25687571
    [TBL] [Abstract][Full Text] [Related]  

  • 36. 10-Formyl-5,10-dideaza-acyclic-5,6,7,8-tetrahydrofolic acid (10-formyl-DDACTHF): a potent cytotoxic agent acting by selective inhibition of human GAR Tfase and the de novo purine biosynthetic pathway.
    Marsilje TH; Labroli MA; Hedrick MP; Jin Q; Desharnais J; Baker SJ; Gooljarsingh LT; Ramcharan J; Tavassoli A; Zhang Y; Wilson IA; Beardsley GP; Benkovic SJ; Boger DL
    Bioorg Med Chem; 2002 Aug; 10(8):2739-49. PubMed ID: 12057663
    [TBL] [Abstract][Full Text] [Related]  

  • 37. ATIC inhibits autophagy in hepatocellular cancer through the AKT/FOXO3 pathway and serves as a prognostic signature for modeling patient survival.
    Zhang H; Xia P; Liu J; Chen Z; Ma W; Yuan Y
    Int J Biol Sci; 2021; 17(15):4442-4458. PubMed ID: 34803509
    [No Abstract]   [Full Text] [Related]  

  • 38. The human purH gene product, 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. Cloning, sequencing, expression, purification, kinetic analysis, and domain mapping.
    Rayl EA; Moroson BA; Beardsley GP
    J Biol Chem; 1996 Jan; 271(4):2225-33. PubMed ID: 8567683
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Characterization of molecularly cloned human 5-aminoimidazole-4-carboxamide ribonucleotide transformylase.
    Sugita T; Aya H; Ueno M; Ishizuka T; Kawashima K
    J Biochem; 1997 Aug; 122(2):309-13. PubMed ID: 9378707
    [TBL] [Abstract][Full Text] [Related]  

  • 40. [The second half of de novo synthetic pathway of IMP and conversion of IMP to AMP].
    Oka J
    Nihon Rinsho; 2003 Jan; 61 Suppl 1():52-8. PubMed ID: 12629690
    [No Abstract]   [Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.