262 related articles for article (PubMed ID: 2906593)
1. Enzymatic conjugation of hexachloro-1,3-butadiene with glutathione. Formation of 1-(glutathion-S-yl)-1,2,3,4,4-pentachlorobuta-1,3-diene and 1,4-bis(glutathion-S-yl)-1,2,3,4-tetrachlorobuta-1,3-diene.
Dekant W; Vamvakas S; Henschler D; Anders MW
Drug Metab Dispos; 1988; 16(5):701-6. PubMed ID: 2906593
[TBL] [Abstract][Full Text] [Related]
2. Metabolism of hexachloro-1,3-butadiene in mice: in vivo and in vitro evidence for activation by glutathione conjugation.
Dekant W; Schrenk D; Vamvakas S; Henschler D
Xenobiotica; 1988 Jul; 18(7):803-16. PubMed ID: 3176519
[TBL] [Abstract][Full Text] [Related]
3. Role of microsomal and cytosolic glutathione S-transferases in the conjugation of hexachloro-1:3-butadiene and its possible relevance to toxicity.
Wolf CR; Berry PN; Nash JA; Green T; Lock EA
J Pharmacol Exp Ther; 1984 Jan; 228(1):202-8. PubMed ID: 6694103
[TBL] [Abstract][Full Text] [Related]
4. Mutagenicity of hexachloro-1,3-butadiene and its S-conjugates in the Ames test--role of activation by the mercapturic acid pathway in its nephrocarcinogenicity.
Vamvakas S; Kordowich FJ; Dekant W; Neudecker T; Henschler D
Carcinogenesis; 1988 Jun; 9(6):907-10. PubMed ID: 3286031
[TBL] [Abstract][Full Text] [Related]
5. Stereo- and regioselective conjugation of S-halovinyl mercapturic acid sulfoxides by glutathione S-transferases.
Rosner E; Müller M; Dekant W
Chem Res Toxicol; 1998 Jan; 11(1):12-8. PubMed ID: 9477221
[TBL] [Abstract][Full Text] [Related]
6. Bioactivation of tetrachloroethylene. Role of glutathione S-transferase-catalyzed conjugation versus cytochrome P-450-dependent phospholipid alkylation.
Dekant W; Martens G; Vamvakas S; Metzler M; Henschler D
Drug Metab Dispos; 1987; 15(5):702-9. PubMed ID: 2891489
[TBL] [Abstract][Full Text] [Related]
7. Biotransformation, excretion, and nephrotoxicity of the hexachlorobutadiene metabolite (E)-N-acetyl-S-(1,2,3,4, 4-pentachlorobutadienyl)-L-cysteine sulfoxide.
Birner G; Werner M; Rosner E; Mehler C; Dekant W
Chem Res Toxicol; 1998 Jul; 11(7):750-7. PubMed ID: 9671537
[TBL] [Abstract][Full Text] [Related]
8. Biotransformation of the hexachlorobutadiene metabolites 1-(glutathion-S-yl)-pentachlorobutadiene and 1-(cystein-S-yl)-pentachlorobutadiene in the isolated perfused rat liver.
Koob M; Dekant W
Xenobiotica; 1992 Jan; 22(1):125-38. PubMed ID: 1615703
[TBL] [Abstract][Full Text] [Related]
9. Stereoselectivity of naphthalene epoxidation by mouse, rat, and hamster pulmonary, hepatic, and renal microsomal enzymes.
Buckpitt AR; Castagnoli N; Nelson SD; Jones AD; Bahnson LS
Drug Metab Dispos; 1987; 15(4):491-8. PubMed ID: 2888622
[TBL] [Abstract][Full Text] [Related]
10. Assessment of the role of glutathione conjugation in the protection afforded by anethol dithiolthione against hexachloro-1,3-butadiene-induced nephrotoxicity.
Bouthillier L; Charbonneau M; Brodeur J
Toxicol Appl Pharmacol; 1996 Jul; 139(1):177-85. PubMed ID: 8685901
[TBL] [Abstract][Full Text] [Related]
11. Conjugation of glutathione with a toxic metabolite of valproic acid, (E)-2-propyl-2,4-pentadienoic acid, catalyzed by rat hepatic glutathione-S-transferases.
Tang W; Borel AG; Abbott FS
Drug Metab Dispos; 1996 Apr; 24(4):436-46. PubMed ID: 8801059
[TBL] [Abstract][Full Text] [Related]
12. Metabolism of hexafluoropropene. Evidence for bioactivation by glutathione conjugate formation in the kidney.
Koob M; Dekant W
Drug Metab Dispos; 1990; 18(6):911-6. PubMed ID: 1981536
[TBL] [Abstract][Full Text] [Related]
13. The formation of both a mono- and a bis-substituted glutathione conjugate of hexachlorobutadiene by isolated hepatocytes and following in vivo administration to the rat.
Jones TW; Gerdes RG; Ormstad K; Orrenius S
Chem Biol Interact; 1985 Dec; 56(2-3):251-67. PubMed ID: 4075451
[TBL] [Abstract][Full Text] [Related]
14. Sex differences in hexachlorobutadiene biotransformation and nephrotoxicity.
Birner G; Werner M; Ott MM; Dekant W
Toxicol Appl Pharmacol; 1995 Jun; 132(2):203-12. PubMed ID: 7785049
[TBL] [Abstract][Full Text] [Related]
15. Identification and characterization of the glutathione and N-acetylcysteine conjugates of (E)-2-propyl-2,4-pentadienoic acid, a toxic metabolite of valproic acid, in rats and humans.
Kassahun K; Farrell K; Abbott F
Drug Metab Dispos; 1991; 19(2):525-35. PubMed ID: 1676665
[TBL] [Abstract][Full Text] [Related]
16. Bioactivation of hexachlorobutadiene by glutathione conjugation.
Dekant W; Vamvakas S; Anders MW
Food Chem Toxicol; 1990 Apr; 28(4):285-93. PubMed ID: 2192968
[TBL] [Abstract][Full Text] [Related]
17. Identification in rat bile of glutathione conjugates of fluoromethyl 2,2-difluoro-1-(trifluoromethyl)vinyl ether, a nephrotoxic degradate of the anesthetic agent sevoflurane.
Jin L; Davis MR; Kharasch ED; Doss GA; Baillie TA
Chem Res Toxicol; 1996 Mar; 9(2):555-61. PubMed ID: 8839062
[TBL] [Abstract][Full Text] [Related]
18. Glutathione conjugation of perchloroethylene in rats and mice in vitro: sex-, species-, and tissue-dependent differences.
Lash LH; Qian W; Putt DA; Desai K; Elfarra AA; Sicuri AR; Parker JC
Toxicol Appl Pharmacol; 1998 May; 150(1):49-57. PubMed ID: 9630452
[TBL] [Abstract][Full Text] [Related]
19. Glutathione conjugation of trichloroethylene in rats and mice: sex-, species-, and tissue-dependent differences.
Lash LH; Qian W; Putt DA; Jacobs K; Elfarra AA; Krause RJ; Parker JC
Drug Metab Dispos; 1998 Jan; 26(1):12-9. PubMed ID: 9443846
[TBL] [Abstract][Full Text] [Related]
20. Glutathione S-conjugation of the sevoflurane degradation product, fluoromethyl-2,2-difluoro-1-(trifluoromethyl)vinyl ether (compound A) in human liver, kidney, and blood in vitro.
Altuntas TG; Kharasch ED
Toxicol Appl Pharmacol; 2001 Dec; 177(2):85-93. PubMed ID: 11740907
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
