BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

180 related articles for article (PubMed ID: 29066190)

  • 21. Obatoclax analog SC-2001 inhibits STAT3 phosphorylation through enhancing SHP-1 expression and induces apoptosis in human breast cancer cells.
    Liu CY; Su JC; Ni MH; Tseng LM; Chu PY; Wang DS; Tai WT; Kao YP; Hung MH; Shiau CW; Chen KF
    Breast Cancer Res Treat; 2014 Jul; 146(1):71-84. PubMed ID: 24903225
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Novel aminotetrazole derivatives as selective STAT3 non-peptide inhibitors.
    Pallandre JR; Borg C; Rognan D; Boibessot T; Luzet V; Yesylevskyy S; Ramseyer C; Pudlo M
    Eur J Med Chem; 2015 Oct; 103():163-74. PubMed ID: 26352675
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Synthesis and biological evaluation of sulfur-containing shikonin oxime derivatives as potential antineoplastic agents.
    Huang G; Zhao HR; Meng QQ; Zhang QJ; Dong JY; Zhu BQ; Li SS
    Eur J Med Chem; 2018 Jan; 143():166-181. PubMed ID: 29174813
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Discovery of new benzensulfonamide derivatives as tripedal STAT3 inhibitors.
    Guo J; Yu W; Cai G; Zhang W; Li S; Zhu J; Song D; Kong L
    Eur J Med Chem; 2018 May; 151():752-764. PubMed ID: 29674294
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Design, synthesis and biological evaluation of cinnamic acyl shikonin derivatives.
    Lin HY; Chen W; Shi J; Kong WY; Qi JL; Wang XM; Yang YH
    Chem Biol Drug Des; 2013 Feb; 81(2):275-83. PubMed ID: 23066914
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Identification of galiellalactone-based novel STAT3-selective inhibitors with cytotoxic activities against triple-negative breast cancer cell lines.
    Kim HS; Kim T; Ko H; Lee J; Kim YS; Suh YG
    Bioorg Med Chem; 2017 Oct; 25(19):5032-5040. PubMed ID: 28705432
    [TBL] [Abstract][Full Text] [Related]  

  • 27. 8-benzyl-4-oxo-8-azabicyclo[3.2.1]oct-2-ene-6,7-dicarboxylic acid (SD-1008), a novel janus kinase 2 inhibitor, increases chemotherapy sensitivity in human ovarian cancer cells.
    Duan Z; Bradner J; Greenberg E; Mazitschek R; Foster R; Mahoney J; Seiden MV
    Mol Pharmacol; 2007 Nov; 72(5):1137-45. PubMed ID: 17675586
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Design and characterization of α-lipoic acyl shikonin ester twin drugs as tubulin and PDK1 dual inhibitors.
    Lin HY; Han HW; Sun WX; Yang YS; Tang CY; Lu GH; Qi JL; Wang XM; Yang YH
    Eur J Med Chem; 2018 Jan; 144():137-150. PubMed ID: 29268130
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Antiproliferative activities and SAR studies of substituted anthraquinones and 1,4-naphthoquinones.
    Bhasin D; Etter JP; Chettiar SN; Mok M; Li PK
    Bioorg Med Chem Lett; 2013 Dec; 23(24):6864-7. PubMed ID: 24176397
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Screening and biological evaluation of a novel STAT3 signaling pathway inhibitor against cancer.
    Huang M; Chen Z; Zhang L; Huang Z; Chen Y; Xu J; Zhang J; Shu X
    Bioorg Med Chem Lett; 2016 Nov; 26(21):5172-5176. PubMed ID: 27727126
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Anticancer phytochemical analogs 37: synthesis, characterization, molecular docking and cytotoxicity of novel plumbagin hydrazones against breast cancer cells.
    Dandawate P; Ahmad A; Deshpande J; Swamy KV; Khan EM; Khetmalas M; Padhye S; Sarkar F
    Bioorg Med Chem Lett; 2014 Jul; 24(13):2900-4. PubMed ID: 24835626
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Rationally designed inhibitors identify STAT3 N-domain as a promising anticancer drug target.
    Timofeeva OA; Gaponenko V; Lockett SJ; Tarasov SG; Jiang S; Michejda CJ; Perantoni AO; Tarasova NI
    ACS Chem Biol; 2007 Dec; 2(12):799-809. PubMed ID: 18154267
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Design, synthesis and activity of novel 2,6-disubstituted purine derivatives, potential small molecule inhibitors of signal transducer and activator of transcription 3.
    Wang X; He Q; Wu K; Guo T; Du X; Zhang H; Fang L; Zheng N; Zhang Q; Ye F
    Eur J Med Chem; 2019 Oct; 179():218-232. PubMed ID: 31254923
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Design, synthesis and structure-activity relationship of a focused library of β-phenylalanine derivatives as novel eEF2K inhibitors with apoptosis-inducing mechanisms in breast cancer.
    Guo Y; Zhao Y; Wang G; Chen Y; Jiang Y; Ouyang L; Liu B
    Eur J Med Chem; 2018 Jan; 143():402-418. PubMed ID: 29202403
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Shikonin selectively induces apoptosis in human prostate cancer cells through the endoplasmic reticulum stress and mitochondrial apoptotic pathway.
    Gara RK; Srivastava VK; Duggal S; Bagga JK; Bhatt M; Sanyal S; Mishra DP
    J Biomed Sci; 2015 Apr; 22(1):26. PubMed ID: 25879420
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Combination Treatment Using Pyruvate Kinase M2 Inhibitors for the Sensitization of High Density Triple-negative Breast Cancer Cells.
    Lee JS; Oh Y; Lee JS; Park JH; Shin JK; Han JH; Kim HS; Yoon S
    In Vivo; 2022; 36(5):2105-2115. PubMed ID: 36099094
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Effective down-regulation of signal transducer and activator of transcription 3 (STAT3) by polyplexes of siRNA and lipid-substituted polyethyleneimine for sensitization of breast tumor cells to conventional chemotherapy.
    Falamarzian A; Aliabadi HM; Molavi O; Seubert JM; Lai R; Uludağ H; Lavasanifar A
    J Biomed Mater Res A; 2014 Sep; 102(9):3216-28. PubMed ID: 24167124
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Synthesis and Evaluation of New Naphthalene and Naphthoquinone Derivatives as Anticancer Agents.
    Beretta GL; Ribaudo G; Menegazzo I; Supino R; Capranico G; Zunino F; Zagotto G
    Arch Pharm (Weinheim); 2017 Jan; 350(1):. PubMed ID: 27990691
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Design, synthesis, and studies of small molecule STAT3 inhibitors.
    Bhasin D; Cisek K; Pandharkar T; Regan N; Li C; Pandit B; Lin J; Li PK
    Bioorg Med Chem Lett; 2008 Jan; 18(1):391-5. PubMed ID: 18006313
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Synthesis and anticancer activity of some novel 5,6-fused hybrids of juglone based 1,4-naphthoquinones.
    Mallavadhani UV; Prasad CV; Shrivastava S; Naidu VG
    Eur J Med Chem; 2014 Aug; 83():84-91. PubMed ID: 24953027
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.