486 related articles for article (PubMed ID: 29069390)
1. CRIMEtoYHU: a new web tool to develop yeast-based functional assays for characterizing cancer-associated missense variants.
Mercatanti A; Lodovichi S; Cervelli T; Galli A
FEMS Yeast Res; 2017 Dec; 17(8):. PubMed ID: 29069390
[TBL] [Abstract][Full Text] [Related]
2. Human MutL homolog (MLH1) function in DNA mismatch repair: a prospective screen for missense mutations in the ATPase domain.
Ellison AR; Lofing J; Bitter GA
Nucleic Acids Res; 2004; 32(18):5321-38. PubMed ID: 15475387
[TBL] [Abstract][Full Text] [Related]
3. BRCA1 Circos: a visualisation resource for functional analysis of missense variants.
Jhuraney A; Velkova A; Johnson RC; Kessing B; Carvalho RS; Whiley P; Spurdle AB; Vreeswijk MP; Caputo SM; Millot GA; Vega A; Coquelle N; Galli A; Eccles D; Blok MJ; Pal T; van der Luijt RB; Santamariña Pena M; Neuhausen SL; Donenberg T; Machackova E; Thomas S; Vallée M; Couch FJ; Tavtigian SV; Glover JN; Carvalho MA; Brody LC; Sharan SK; Monteiro AN;
J Med Genet; 2015 Apr; 52(4):224-30. PubMed ID: 25643705
[TBL] [Abstract][Full Text] [Related]
4. A yeast recombination assay to characterize human BRCA1 missense variants of unknown pathological significance.
Caligo MA; Bonatti F; Guidugli L; Aretini P; Galli A
Hum Mutat; 2009 Jan; 30(1):123-33. PubMed ID: 18680205
[TBL] [Abstract][Full Text] [Related]
5. Effect of the expression of BRCA2 on spontaneous homologous recombination and DNA damage-induced nuclear foci in Saccharomyces cerevisiae.
Spugnesi L; Balia C; Collavoli A; Falaschi E; Quercioli V; Caligo MA; Galli A
Mutagenesis; 2013 Mar; 28(2):187-95. PubMed ID: 23328489
[TBL] [Abstract][Full Text] [Related]
6. UMD-predictor, a new prediction tool for nucleotide substitution pathogenicity -- application to four genes: FBN1, FBN2, TGFBR1, and TGFBR2.
Frédéric MY; Lalande M; Boileau C; Hamroun D; Claustres M; Béroud C; Collod-Béroud G
Hum Mutat; 2009 Jun; 30(6):952-9. PubMed ID: 19370756
[TBL] [Abstract][Full Text] [Related]
7. Detailed computational study of p53 and p16: using evolutionary sequence analysis and disease-associated mutations to predict the functional consequences of allelic variants.
Greenblatt MS; Beaudet JG; Gump JR; Godin KS; Trombley L; Koh J; Bond JP
Oncogene; 2003 Feb; 22(8):1150-63. PubMed ID: 12606942
[TBL] [Abstract][Full Text] [Related]
8. Predicting the functional consequences of somatic missense mutations found in tumors.
Carter H; Karchin R
Methods Mol Biol; 2014; 1101():135-59. PubMed ID: 24233781
[TBL] [Abstract][Full Text] [Related]
9. Assessment of human Nter and Cter BRCA1 mutations using growth and localization assays in yeast.
Millot GA; Berger A; Lejour V; Boulé JB; Bobo C; Cullin C; Lopes J; Stoppa-Lyonnet D; Nicolas A
Hum Mutat; 2011 Dec; 32(12):1470-80. PubMed ID: 21922593
[TBL] [Abstract][Full Text] [Related]
10. Characterisation of gene expression profiles of yeast cells expressing BRCA1 missense variants.
Di Cecco L; Melissari E; Mariotti V; Iofrida C; Galli A; Guidugli L; Lombardi G; Caligo MA; Iacopetti P; Pellegrini S
Eur J Cancer; 2009 Aug; 45(12):2187-96. PubMed ID: 19493677
[TBL] [Abstract][Full Text] [Related]
11. Functional characterization of BRCA1 sequence variants using a yeast small colony phenotype assay.
Coyne RS; McDonald HB; Edgemon K; Brody LC
Cancer Biol Ther; 2004 May; 3(5):453-7. PubMed ID: 15004537
[TBL] [Abstract][Full Text] [Related]
12. Machine learning classifier for identification of damaging missense mutations exclusive to human mitochondrial DNA-encoded polypeptides.
Martín-Navarro A; Gaudioso-Simón A; Álvarez-Jarreta J; Montoya J; Mayordomo E; Ruiz-Pesini E
BMC Bioinformatics; 2017 Mar; 18(1):158. PubMed ID: 28270093
[TBL] [Abstract][Full Text] [Related]
13. An extended set of yeast-based functional assays accurately identifies human disease mutations.
Sun S; Yang F; Tan G; Costanzo M; Oughtred R; Hirschman J; Theesfeld CL; Bansal P; Sahni N; Yi S; Yu A; Tyagi T; Tie C; Hill DE; Vidal M; Andrews BJ; Boone C; Dolinski K; Roth FP
Genome Res; 2016 May; 26(5):670-80. PubMed ID: 26975778
[TBL] [Abstract][Full Text] [Related]
14. Novel human p53 mutations that are toxic to yeast can enhance transactivation of specific promoters and reactivate tumor p53 mutants.
Inga A; Resnick MA
Oncogene; 2001 Jun; 20(26):3409-19. PubMed ID: 11423991
[TBL] [Abstract][Full Text] [Related]
15. Interpreting missense variants: comparing computational methods in human disease genes CDKN2A, MLH1, MSH2, MECP2, and tyrosinase (TYR).
Chan PA; Duraisamy S; Miller PJ; Newell JA; McBride C; Bond JP; Raevaara T; Ollila S; Nyström M; Grimm AJ; Christodoulou J; Oetting WS; Greenblatt MS
Hum Mutat; 2007 Jul; 28(7):683-93. PubMed ID: 17370310
[TBL] [Abstract][Full Text] [Related]
16. Predicting the oncogenicity of missense mutations reported in the International Agency for Cancer Research (IARC) mutation database on p53.
Gorlov IP; Gorlova OY; Amos CI
Hum Mutat; 2005 Nov; 26(5):446-54. PubMed ID: 16173033
[TBL] [Abstract][Full Text] [Related]
17. KVarPredDB: a database for predicting pathogenicity of missense sequence variants of keratin genes associated with genodermatoses.
Ying Y; Lu L; Banerjee S; Xu L; Zhao Q; Wu H; Li R; Xu X; Yu H; Neculai D; Xi Y; Yang F; Qin J; Li C
Hum Genomics; 2020 Dec; 14(1):45. PubMed ID: 33287903
[TBL] [Abstract][Full Text] [Related]
18. Comprehensive characterization of amino acid positions in protein structures reveals molecular effect of missense variants.
Iqbal S; Pérez-Palma E; Jespersen JB; May P; Hoksza D; Heyne HO; Ahmed SS; Rifat ZT; Rahman MS; Lage K; Palotie A; Cottrell JR; Wagner FF; Daly MJ; Campbell AJ; Lal D
Proc Natl Acad Sci U S A; 2020 Nov; 117(45):28201-28211. PubMed ID: 33106425
[TBL] [Abstract][Full Text] [Related]
19. Yeast-based assays for the functional characterization of cancer-associated variants of human DNA repair genes.
Cervelli T; Lodovichi S; Bellè F; Galli A
Microb Cell; 2020 May; 7(7):162-174. PubMed ID: 32656256
[TBL] [Abstract][Full Text] [Related]
20. Structure-Based Analysis Reveals Cancer Missense Mutations Target Protein Interaction Interfaces.
Engin HB; Kreisberg JF; Carter H
PLoS One; 2016; 11(4):e0152929. PubMed ID: 27043210
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
