BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

147 related articles for article (PubMed ID: 29074538)

  • 1. TGFβ Promotes Genomic Instability after Loss of RUNX3.
    Krishnan V; Chong YL; Tan TZ; Kulkarni M; Bin Rahmat MB; Tay LS; Sankar H; Jokhun DS; Ganesan A; Chuang LSH; Voon DC; Shivashankar GV; Thiery JP; Ito Y
    Cancer Res; 2018 Jan; 78(1):88-102. PubMed ID: 29074538
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PARP3 controls TGFβ and ROS driven epithelial-to-mesenchymal transition and stemness by stimulating a TG2-Snail-E-cadherin axis.
    Karicheva O; Rodriguez-Vargas JM; Wadier N; Martin-Hernandez K; Vauchelles R; Magroun N; Tissier A; Schreiber V; Dantzer F
    Oncotarget; 2016 Sep; 7(39):64109-64123. PubMed ID: 27579892
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Runx3 protects gastric epithelial cells against epithelial-mesenchymal transition-induced cellular plasticity and tumorigenicity.
    Voon DC; Wang H; Koo JK; Nguyen TA; Hor YT; Chu YS; Ito K; Fukamachi H; Chan SL; Thiery JP; Ito Y
    Stem Cells; 2012 Oct; 30(10):2088-99. PubMed ID: 22899304
    [TBL] [Abstract][Full Text] [Related]  

  • 4. New tricks for an old fox: impact of TGFβ on the DNA damage response and genomic stability.
    Barcellos-Hoff MH; Cucinotta FA
    Sci Signal; 2014 Sep; 7(341):re5. PubMed ID: 25185158
    [TBL] [Abstract][Full Text] [Related]  

  • 5. DNA methylation-associated inactivation of TGFbeta-related genes DRM/Gremlin, RUNX3, and HPP1 in human cancers.
    Suzuki M; Shigematsu H; Shames DS; Sunaga N; Takahashi T; Shivapurkar N; Iizasa T; Frenkel EP; Minna JD; Fujisawa T; Gazdar AF
    Br J Cancer; 2005 Oct; 93(9):1029-37. PubMed ID: 16234815
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A Regulatory Role for RUNX1, RUNX3 in the Maintenance of Genomic Integrity.
    Krishnan V; Ito Y
    Adv Exp Med Biol; 2017; 962():491-510. PubMed ID: 28299675
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hypermethylation downregulates Runx3 gene expression and its restoration suppresses gastric epithelial cell growth by inducing p27 and caspase3 in human gastric cancer.
    Chen W; Gao N; Shen Y; Cen JN
    J Gastroenterol Hepatol; 2010 Apr; 25(4):823-31. PubMed ID: 20492341
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Runt-related transcription factor 3 reverses epithelial-mesenchymal transition in hepatocellular carcinoma.
    Tanaka S; Shiraha H; Nakanishi Y; Nishina S; Matsubara M; Horiguchi S; Takaoka N; Iwamuro M; Kataoka J; Kuwaki K; Hagihara H; Toshimori J; Ohnishi H; Takaki A; Nakamura S; Nouso K; Yagi T; Yamamoto K
    Int J Cancer; 2012 Dec; 131(11):2537-46. PubMed ID: 22488108
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The RUNX3 tumor suppressor upregulates Bim in gastric epithelial cells undergoing transforming growth factor beta-induced apoptosis.
    Yano T; Ito K; Fukamachi H; Chi XZ; Wee HJ; Inoue K; Ida H; Bouillet P; Strasser A; Bae SC; Ito Y
    Mol Cell Biol; 2006 Jun; 26(12):4474-88. PubMed ID: 16738314
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Restored expression of the tumor suppressor gene RUNX3 reduces cancer stem cells in hepatocellular carcinoma by suppressing Jagged1-Notch signaling.
    Nishina S; Shiraha H; Nakanishi Y; Tanaka S; Matsubara M; Takaoka N; Uemura M; Horiguchi S; Kataoka J; Iwamuro M; Yagi T; Yamamoto K
    Oncol Rep; 2011 Sep; 26(3):523-31. PubMed ID: 21637926
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Esophageal Adenocarcinoma Cells and Xenograft Tumors Exposed to Erb-b2 Receptor Tyrosine Kinase 2 and 3 Inhibitors Activate Transforming Growth Factor Beta Signaling, Which Induces Epithelial to Mesenchymal Transition.
    Ebbing EA; Steins A; Fessler E; Stathi P; Lesterhuis WJ; Krishnadath KK; Vermeulen L; Medema JP; Bijlsma MF; van Laarhoven HWM
    Gastroenterology; 2017 Jul; 153(1):63-76.e14. PubMed ID: 28286209
    [TBL] [Abstract][Full Text] [Related]  

  • 12. IFNγ induces oxidative stress, DNA damage and tumor cell senescence via TGFβ/SMAD signaling-dependent induction of Nox4 and suppression of ANT2.
    Hubackova S; Kucerova A; Michlits G; Kyjacova L; Reinis M; Korolov O; Bartek J; Hodny Z
    Oncogene; 2016 Mar; 35(10):1236-49. PubMed ID: 25982278
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Vitamin D/vitamin D receptor axis regulates DNA repair during oncogene-induced senescence.
    Graziano S; Johnston R; Deng O; Zhang J; Gonzalo S
    Oncogene; 2016 Oct; 35(41):5362-5376. PubMed ID: 27041576
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Oxidative stress induces proliferation of colorectal cancer cells by inhibiting RUNX3 and activating the Akt signaling pathway.
    Kang KA; Kim KC; Bae SC; Hyun JW
    Int J Oncol; 2013 Nov; 43(5):1511-6. PubMed ID: 24042352
    [TBL] [Abstract][Full Text] [Related]  

  • 15. RUNX3 modulates DNA damage-mediated phosphorylation of tumor suppressor p53 at Ser-15 and acts as a co-activator for p53.
    Yamada C; Ozaki T; Ando K; Suenaga Y; Inoue K; Ito Y; Okoshi R; Kageyama H; Kimura H; Miyazaki M; Nakagawara A
    J Biol Chem; 2010 May; 285(22):16693-703. PubMed ID: 20353948
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effect of histone deacetylase inhibitors on cell apoptosis and expression of the tumor suppressor genes RUNX3 and ARHI in ovarian tumors.
    Zhang L; Liu P; Li H; Xue F
    Mol Med Rep; 2013 May; 7(5):1705-9. PubMed ID: 23504001
    [TBL] [Abstract][Full Text] [Related]  

  • 17. RUNX3 suppresses gastric epithelial cell growth by inducing p21(WAF1/Cip1) expression in cooperation with transforming growth factor {beta}-activated SMAD.
    Chi XZ; Yang JO; Lee KY; Ito K; Sakakura C; Li QL; Kim HR; Cha EJ; Lee YH; Kaneda A; Ushijima T; Kim WJ; Ito Y; Bae SC
    Mol Cell Biol; 2005 Sep; 25(18):8097-107. PubMed ID: 16135801
    [TBL] [Abstract][Full Text] [Related]  

  • 18. RUNX3 inhibits laryngeal squamous cell carcinoma malignancy under the regulation of miR-148a-3p/DNMT1 axis.
    Jili S; Eryong L; Lijuan L; Chao Z
    Cell Biochem Funct; 2016 Dec; 34(8):597-605. PubMed ID: 27859417
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The emerging role of RUNX3 in cancer metastasis (Review).
    Chen F; Liu X; Bai J; Pei D; Zheng J
    Oncol Rep; 2016 Mar; 35(3):1227-36. PubMed ID: 26708741
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Methylation of the RUNX3 promoter as a potential prognostic marker for bladder tumor.
    Kim EJ; Kim YJ; Jeong P; Ha YS; Bae SC; Kim WJ
    J Urol; 2008 Sep; 180(3):1141-5. PubMed ID: 18639281
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.