280 related articles for article (PubMed ID: 29074774)
1. Plasmepsins IX and X are essential and druggable mediators of malaria parasite egress and invasion.
Nasamu AS; Glushakova S; Russo I; Vaupel B; Oksman A; Kim AS; Fremont DH; Tolia N; Beck JR; Meyers MJ; Niles JC; Zimmerberg J; Goldberg DE
Science; 2017 Oct; 358(6362):518-522. PubMed ID: 29074774
[TBL] [Abstract][Full Text] [Related]
2. Dual Plasmepsin-Targeting Antimalarial Agents Disrupt Multiple Stages of the Malaria Parasite Life Cycle.
Favuzza P; de Lera Ruiz M; Thompson JK; Triglia T; Ngo A; Steel RWJ; Vavrek M; Christensen J; Healer J; Boyce C; Guo Z; Hu M; Khan T; Murgolo N; Zhao L; Penington JS; Reaksudsan K; Jarman K; Dietrich MH; Richardson L; Guo KY; Lopaticki S; Tham WH; Rottmann M; Papenfuss T; Robbins JA; Boddey JA; Sleebs BE; Sabroux HJ; McCauley JA; Olsen DB; Cowman AF
Cell Host Microbe; 2020 Apr; 27(4):642-658.e12. PubMed ID: 32109369
[TBL] [Abstract][Full Text] [Related]
3. Malaria parasite plasmepsins: More than just plain old degradative pepsins.
Nasamu AS; Polino AJ; Istvan ES; Goldberg DE
J Biol Chem; 2020 Jun; 295(25):8425-8441. PubMed ID: 32366462
[TBL] [Abstract][Full Text] [Related]
4. Prodomain-driven enzyme dimerization: a pH-dependent autoinhibition mechanism that controls
Martinez M; Bouillon A; Brûlé S; Raynal B; Haouz A; Alzari PM; Barale J-C
mBio; 2024 Mar; 15(3):e0019824. PubMed ID: 38386597
[TBL] [Abstract][Full Text] [Related]
5. Activation of the
Mukherjee S; Nasamu AS; Rubiano KC; Goldberg DE
mBio; 2023 Apr; 14(2):e0067323. PubMed ID: 37036362
[TBL] [Abstract][Full Text] [Related]
6. In Silico screening on the three-dimensional model of the Plasmodium vivax SUB1 protease leads to the validation of a novel anti-parasite compound.
Bouillon A; Giganti D; Benedet C; Gorgette O; Pêtres S; Crublet E; Girard-Blanc C; Witkowski B; Ménard D; Nilges M; Mercereau-Puijalon O; Stoven V; Barale JC
J Biol Chem; 2013 Jun; 288(25):18561-73. PubMed ID: 23653352
[TBL] [Abstract][Full Text] [Related]
7. Plasmodium falciparum proteases as new drug targets with special focus on metalloproteases.
Mahanta PJ; Lhouvum K
Mol Biochem Parasitol; 2024 Jun; 258():111617. PubMed ID: 38554736
[TBL] [Abstract][Full Text] [Related]
8. Maturation and substrate processing topography of the Plasmodium falciparum invasion/egress protease plasmepsin X.
Mukherjee S; Nguyen S; Sharma E; Goldberg DE
Nat Commun; 2022 Aug; 13(1):4537. PubMed ID: 35927261
[TBL] [Abstract][Full Text] [Related]
9. Four plasmepsins are active in the Plasmodium falciparum food vacuole, including a protease with an active-site histidine.
Banerjee R; Liu J; Beatty W; Pelosof L; Klemba M; Goldberg DE
Proc Natl Acad Sci U S A; 2002 Jan; 99(2):990-5. PubMed ID: 11782538
[TBL] [Abstract][Full Text] [Related]
10. Proteolytic activation of the essential parasitophorous vacuole cysteine protease SERA6 accompanies malaria parasite egress from its host erythrocyte.
Ruecker A; Shea M; Hackett F; Suarez C; Hirst EM; Milutinovic K; Withers-Martinez C; Blackman MJ
J Biol Chem; 2012 Nov; 287(45):37949-63. PubMed ID: 22984267
[TBL] [Abstract][Full Text] [Related]
11. A proteomic glimpse into the effect of antimalarial drugs on Plasmodium falciparum proteome towards highlighting possible therapeutic targets.
Dousti M; Manzano-Román R; Rashidi S; Barzegar G; Ahmadpour NB; Mohammadi A; Hatam G
Pathog Dis; 2021 Jan; 79(1):. PubMed ID: 33202000
[TBL] [Abstract][Full Text] [Related]
12. Plasmodium falciparum subtilisin-like protease 2, a merozoite candidate for the merozoite surface protein 1-42 maturase.
Barale JC; Blisnick T; Fujioka H; Alzari PM; Aikawa M; Braun-Breton C; Langsley G
Proc Natl Acad Sci U S A; 1999 May; 96(11):6445-50. PubMed ID: 10339607
[TBL] [Abstract][Full Text] [Related]
13. Insights from structure-activity relationships and the binding mode of peptidic α-ketoamide inhibitors of the malaria drug target subtilisin-like SUB1.
Legru A; Batista FA; Puszko AK; Bouillon A; Maurel M; Martinez M; Ejjoummany A; Ortega Varga L; Adler P; Méchaly A; Hadjadj M; Sosnowski P; Hopfgartner G; Alzari PM; Blondel A; Haouz A; Barale JC; Hernandez JF
Eur J Med Chem; 2024 Apr; 269():116308. PubMed ID: 38503166
[TBL] [Abstract][Full Text] [Related]
14. The Plasmodium berghei serine protease PbSUB1 plays an important role in male gamete egress.
Pace T; Grasso F; Camarda G; Suarez C; Blackman MJ; Ponzi M; Olivieri A
Cell Microbiol; 2019 Jul; 21(7):e13028. PubMed ID: 30941868
[TBL] [Abstract][Full Text] [Related]
15. Macrocyclic Peptidomimetic Plasmepsin X Inhibitors with Potent
Kovada V; Withers-Martinez C; Bobrovs R; Ce Rule HN; Liepins E; Grinberga S; Hackett F; Collins CR; Kreicberga A; Jiménez-Díaz MB; Angulo-Barturen I; Rasina D; Suna E; Jaudzems K; Blackman MJ; Jirgensons A
J Med Chem; 2023 Aug; 66(15):10658-10680. PubMed ID: 37505188
[TBL] [Abstract][Full Text] [Related]
16. A protease cascade regulates release of the human malaria parasite Plasmodium falciparum from host red blood cells.
Thomas JA; Tan MSY; Bisson C; Borg A; Umrekar TR; Hackett F; Hale VL; Vizcay-Barrena G; Fleck RA; Snijders AP; Saibil HR; Blackman MJ
Nat Microbiol; 2018 Apr; 3(4):447-455. PubMed ID: 29459732
[TBL] [Abstract][Full Text] [Related]
17. Assessment of Biological Role and Insight into Druggability of the
Polino AJ; Nasamu AS; Niles JC; Goldberg DE
ACS Infect Dis; 2020 Apr; 6(4):738-746. PubMed ID: 32069391
[TBL] [Abstract][Full Text] [Related]
18. Computational inhibitor design against malaria plasmepsins.
Bjelic S; Nervall M; Gutiérrez-de-Terán H; Ersmark K; Hallberg A; Aqvist J
Cell Mol Life Sci; 2007 Sep; 64(17):2285-305. PubMed ID: 17585371
[TBL] [Abstract][Full Text] [Related]
19. Antimalarial and
Gupta S; Saini M; Joshi N; Shafi S; Najmi AK; Singh S
J Biomol Struct Dyn; 2023 Nov; 41(19):9462-9475. PubMed ID: 36351236
[TBL] [Abstract][Full Text] [Related]
20. Imidazopyridazines as potent inhibitors of Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1): Preparation and evaluation of pyrazole linked analogues.
Large JM; Osborne SA; Smiljanic-Hurley E; Ansell KH; Jones HM; Taylor DL; Clough B; Green JL; Holder AA
Bioorg Med Chem Lett; 2013 Nov; 23(21):6019-24. PubMed ID: 24035097
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]