182 related articles for article (PubMed ID: 29076755)
21. Design and synthesis of pyrimidine-5-carbonitrile hybrids as COX-2 inhibitors: Anti-inflammatory activity, ulcerogenic liability, histopathological and docking studies.
Alfayomy AM; Abdel-Aziz SA; Marzouk AA; Shaykoon MSA; Narumi A; Konno H; Abou-Seri SM; Ragab FAF
Bioorg Chem; 2021 Mar; 108():104555. PubMed ID: 33376011
[TBL] [Abstract][Full Text] [Related]
22. New benzimidazothiazole derivatives as anti-inflammatory, antitumor active agents: Synthesis, in-vitro and in-vivo screening and molecular modeling studies.
El-Kerdawy MM; Ghaly MA; Darwish SA; Abdel-Aziz HA; Elsheakh AR; Abdelrahman RS; Hassan GS
Bioorg Chem; 2019 Mar; 83():250-261. PubMed ID: 30391698
[TBL] [Abstract][Full Text] [Related]
23. Synthesis, biological evaluation and docking study of a new series of di-substituted benzoxazole derivatives as selective COX-2 inhibitors and anti-inflammatory agents.
Kaur A; Pathak DP; Sharma V; Wakode S
Bioorg Med Chem; 2018 Feb; 26(4):891-902. PubMed ID: 29373271
[TBL] [Abstract][Full Text] [Related]
24. Novel tetrazole and cyanamide derivatives as inhibitors of cyclooxygenase-2 enzyme: design, synthesis, anti-inflammatory evaluation, ulcerogenic liability and docking study.
Lamie PF; Philoppes JN; Azouz AA; Safwat NM
J Enzyme Inhib Med Chem; 2017 Dec; 32(1):805-820. PubMed ID: 28587532
[TBL] [Abstract][Full Text] [Related]
25. Synthesis, cyclooxygenase inhibition, anti-inflammatory evaluation and ulcerogenic liability of novel triarylpyrazoline derivatives as selective COX-2 inhibitors.
Abdellatif KR; Abdelgawad MA; Labib MB; Zidan TH
Bioorg Med Chem Lett; 2015 Dec; 25(24):5787-91. PubMed ID: 26546221
[TBL] [Abstract][Full Text] [Related]
26. Design, synthesis, evaluation and molecular modelling studies of some novel 5,6-diphenyl-1,2,4-triazin-3(2H)-ones bearing five-member heterocyclic moieties as potential COX-2 inhibitors: A hybrid pharmacophore approach.
Banerjee AG; Das N; Shengule SA; Sharma PA; Srivastava RS; Shrivastava SK
Bioorg Chem; 2016 Dec; 69():102-120. PubMed ID: 27750057
[TBL] [Abstract][Full Text] [Related]
27. Design and synthesis of novel 2-phenyl-5-(1,3-diphenyl-1H-pyrazol-4-yl)-1,3,4-oxadiazoles as selective COX-2 inhibitors with potent anti-inflammatory activity.
Bansal S; Bala M; Suthar SK; Choudhary S; Bhattacharya S; Bhardwaj V; Singla S; Joseph A
Eur J Med Chem; 2014 Jun; 80():167-74. PubMed ID: 24780593
[TBL] [Abstract][Full Text] [Related]
28. Design, synthesis of celecoxib-tolmetin drug hybrids as selective and potent COX-2 inhibitors.
Abdellatif KRA; Abdelall EKA; Labib MB; Fadaly WAA; Zidan TH
Bioorg Chem; 2019 Sep; 90():103029. PubMed ID: 31212177
[TBL] [Abstract][Full Text] [Related]
29. Discovery of new indomethacin-based analogs with potentially selective cyclooxygenase-2 inhibition and observed diminishing to PGE2 activities.
Kassab SE; Khedr MA; Ali HI; Abdalla MM
Eur J Med Chem; 2017 Dec; 141():306-321. PubMed ID: 29031075
[TBL] [Abstract][Full Text] [Related]
30. Design, synthesis and biological assessment of new selective COX-2 inhibitors including methyl sulfonyl moiety.
Sağlık BN; Osmaniye D; Levent S; Çevik UA; Çavuşoğlu BK; Özkay Y; Kaplancıklı ZA
Eur J Med Chem; 2021 Jan; 209():112918. PubMed ID: 33071054
[TBL] [Abstract][Full Text] [Related]
31. Pyrazoles containing thiophene, thienopyrimidine and thienotriazolopyrimidine as COX-2 selective inhibitors: Design, synthesis, in vivo anti-inflammatory activity, docking and in silico chemo-informatic studies.
El-Shoukrofy MS; Abd El Razik HA; AboulWafa OM; Bayad AE; El-Ashmawy IM
Bioorg Chem; 2019 Apr; 85():541-557. PubMed ID: 30807897
[TBL] [Abstract][Full Text] [Related]
32. Synthesis of novel N-substitutedphenyl-6-oxo-3-phenylpyridazine derivatives as cyclooxygenase-2 inhibitors.
Khan A; Diwan A; Thabet HK; Imran M
Drug Dev Res; 2020 Aug; 81(5):573-584. PubMed ID: 32173897
[TBL] [Abstract][Full Text] [Related]
33. Synthesis, biological evaluation and docking analysis of 3-methyl-1-phenylchromeno[4,3-c]pyrazol-4(1H)-ones as potential cyclooxygenase-2 (COX-2) inhibitors.
Grover J; Kumar V; Sobhia ME; Jachak SM
Bioorg Med Chem Lett; 2014 Oct; 24(19):4638-4642. PubMed ID: 25219899
[TBL] [Abstract][Full Text] [Related]
34. Cyclooxygenase-2 and 15-lipoxygenase inhibition, synthesis, anti-inflammatory activity and ulcer liability of new celecoxib analogues: Determination of region-specific pyrazole ring formation by NOESY.
Abdelall EKA; Lamie PF; Ali WAM
Bioorg Med Chem Lett; 2016 Jun; 26(12):2893-2899. PubMed ID: 27158139
[TBL] [Abstract][Full Text] [Related]
35. Design, synthesis, and biological evaluation of new pyrazoloquinazoline derivatives as dual COX-2/5-LOX inhibitors.
Shaaban MA; Kamal AM; Faggal SI; Farag NA; Aborehab NM; Elsahar AE; Mohamed KO
Arch Pharm (Weinheim); 2020 Nov; 353(11):e2000027. PubMed ID: 32696514
[TBL] [Abstract][Full Text] [Related]
36. Synthesis, anti-inflammatory, analgesic, COX-1/2 inhibitory activities and molecular docking studies of substituted 2-mercapto-4(3H)-quinazolinones.
Abdel-Aziz AA; Abou-Zeid LA; ElTahir KEH; Ayyad RR; El-Sayed MA; El-Azab AS
Eur J Med Chem; 2016 Oct; 121():410-421. PubMed ID: 27318118
[TBL] [Abstract][Full Text] [Related]
37. Novel 4- Aryl-2(1H)-phthalazinone Derivatives as Cyclooxygenase-2 Inhibitors: Synthesis, Molecular Modeling Study and Evaluation as Promising Anti-inflammatory Agents.
Hasabelnaby S; Mohi El-Deen EM; Goudah A
Antiinflamm Antiallergy Agents Med Chem; 2015; 14(3):148-63. PubMed ID: 26526600
[TBL] [Abstract][Full Text] [Related]
38. Molecular modeling, synthesis and screening of some new 4-thiazolidinone derivatives with promising selective COX-2 inhibitory activity.
Unsal-Tan O; Ozadali K; Piskin K; Balkan A
Eur J Med Chem; 2012 Nov; 57():59-64. PubMed ID: 23047224
[TBL] [Abstract][Full Text] [Related]
39. Design, synthesis, and biological evaluation of linear 1-(4-, 3- or 2-methylsulfonylphenyl)-2-phenylacetylenes: a novel class of cyclooxygenase-2 inhibitors.
Chen QH; Rao PN; Knaus EE
Bioorg Med Chem; 2005 Dec; 13(23):6425-34. PubMed ID: 16099663
[TBL] [Abstract][Full Text] [Related]
40. Synthesis, biological evaluation and docking study of maleimide derivatives bearing benzenesulfonamide as selective COX-2 inhibitors and anti-inflammatory agents.
Firke SD; Bari SB
Bioorg Med Chem; 2015 Sep; 23(17):5273-81. PubMed ID: 26277757
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
