227 related articles for article (PubMed ID: 29078305)
1. β-III-spectrin spinocerebellar ataxia type 5 mutation reveals a dominant cytoskeletal mechanism that underlies dendritic arborization.
Avery AW; Thomas DD; Hays TS
Proc Natl Acad Sci U S A; 2017 Oct; 114(44):E9376-E9385. PubMed ID: 29078305
[TBL] [Abstract][Full Text] [Related]
2. β-III spectrin underpins ankyrin R function in Purkinje cell dendritic trees: protein complex critical for sodium channel activity is impaired by SCA5-associated mutations.
Clarkson YL; Perkins EM; Cairncross CJ; Lyndon AR; Skehel PA; Jackson M
Hum Mol Genet; 2014 Jul; 23(14):3875-82. PubMed ID: 24603075
[TBL] [Abstract][Full Text] [Related]
3. Early-phase drug discovery of β-III-spectrin actin-binding modulators for treatment of spinocerebellar ataxia type 5.
Guhathakurta P; Rebbeck RT; Denha SA; Keller AR; Carter AL; Atang AE; Svensson B; Thomas DD; Hays TS; Avery AW
J Biol Chem; 2023 Mar; 299(3):102956. PubMed ID: 36731793
[TBL] [Abstract][Full Text] [Related]
4. A human β-III-spectrin spinocerebellar ataxia type 5 mutation causes high-affinity F-actin binding.
Avery AW; Crain J; Thomas DD; Hays TS
Sci Rep; 2016 Feb; 6():21375. PubMed ID: 26883385
[TBL] [Abstract][Full Text] [Related]
5. β-III-spectrin N-terminus is required for high-affinity actin binding and SCA5 neurotoxicity.
Denha SA; Atang AE; Hays TS; Avery AW
Sci Rep; 2022 Feb; 12(1):1726. PubMed ID: 35110634
[TBL] [Abstract][Full Text] [Related]
6. Increased Actin Binding Is a Shared Molecular Consequence of Numerous SCA5 Mutations in β-III-Spectrin.
Atang AE; Keller AR; Denha SA; Avery AW
Cells; 2023 Aug; 12(16):. PubMed ID: 37626910
[TBL] [Abstract][Full Text] [Related]
7. βIII spectrin controls the planarity of Purkinje cell dendrites by modulating perpendicular axon-dendrite interactions.
Fujishima K; Kurisu J; Yamada M; Kengaku M
Development; 2020 Dec; 147(24):. PubMed ID: 33234719
[TBL] [Abstract][Full Text] [Related]
8. Novel drug discovery platform for spinocerebellar ataxia, using fluorescence technology targeting β-III-spectrin.
Rebbeck RT; Andrick AK; Denha SA; Svensson B; Guhathakurta P; Thomas DD; Hays TS; Avery AW
J Biol Chem; 2021; 296():100215. PubMed ID: 33839680
[TBL] [Abstract][Full Text] [Related]
9. Beta-III spectrin mutation L253P associated with spinocerebellar ataxia type 5 interferes with binding to Arp1 and protein trafficking from the Golgi.
Clarkson YL; Gillespie T; Perkins EM; Lyndon AR; Jackson M
Hum Mol Genet; 2010 Sep; 19(18):3634-41. PubMed ID: 20603325
[TBL] [Abstract][Full Text] [Related]
10. Mutant β-III spectrin causes mGluR1α mislocalization and functional deficits in a mouse model of spinocerebellar ataxia type 5.
Armbrust KR; Wang X; Hathorn TJ; Cramer SW; Chen G; Zu T; Kangas T; Zink AN; Öz G; Ebner TJ; Ranum LP
J Neurosci; 2014 Jul; 34(30):9891-904. PubMed ID: 25057192
[TBL] [Abstract][Full Text] [Related]
11. Spectrin mutations that cause spinocerebellar ataxia type 5 impair axonal transport and induce neurodegeneration in Drosophila.
Lorenzo DN; Li MG; Mische SE; Armbrust KR; Ranum LP; Hays TS
J Cell Biol; 2010 Apr; 189(1):143-58. PubMed ID: 20368622
[TBL] [Abstract][Full Text] [Related]
12. Spinocerebellar ataxia type 5.
Dick KA; Ikeda Y; Day JW; Ranum LP
Handb Clin Neurol; 2012; 103():451-9. PubMed ID: 21827906
[TBL] [Abstract][Full Text] [Related]
13. Posterior cerebellar Purkinje cells in an SCA5/SPARCA1 mouse model are especially vulnerable to the synergistic effect of loss of β-III spectrin and GLAST.
Perkins EM; Suminaite D; Clarkson YL; Lee SK; Lyndon AR; Rothstein JD; Wyllie DJ; Tanaka K; Jackson M
Hum Mol Genet; 2016 Oct; 25(20):4448-4461. PubMed ID: 28173092
[TBL] [Abstract][Full Text] [Related]
14. Structural basis for high-affinity actin binding revealed by a β-III-spectrin SCA5 missense mutation.
Avery AW; Fealey ME; Wang F; Orlova A; Thompson AR; Thomas DD; Hays TS; Egelman EH
Nat Commun; 2017 Nov; 8(1):1350. PubMed ID: 29116080
[TBL] [Abstract][Full Text] [Related]
15. Loss of beta-III spectrin leads to Purkinje cell dysfunction recapitulating the behavior and neuropathology of spinocerebellar ataxia type 5 in humans.
Perkins EM; Clarkson YL; Sabatier N; Longhurst DM; Millward CP; Jack J; Toraiwa J; Watanabe M; Rothstein JD; Lyndon AR; Wyllie DJ; Dutia MB; Jackson M
J Neurosci; 2010 Apr; 30(14):4857-67. PubMed ID: 20371805
[TBL] [Abstract][Full Text] [Related]
16. Recessive mutations in SPTBN2 implicate β-III spectrin in both cognitive and motor development.
Lise S; Clarkson Y; Perkins E; Kwasniewska A; Sadighi Akha E; Schnekenberg RP; Suminaite D; Hope J; Baker I; Gregory L; Green A; Allan C; Lamble S; Jayawant S; Quaghebeur G; Cader MZ; Hughes S; Armstrong RJ; Kanapin A; Rimmer A; Lunter G; Mathieson I; Cazier JB; Buck D; Taylor JC; Bentley D; McVean G; Donnelly P; Knight SJ; Jackson M; Ragoussis J; Németh AH
PLoS Genet; 2012; 8(12):e1003074. PubMed ID: 23236289
[TBL] [Abstract][Full Text] [Related]
17. Increased actin binding is a shared molecular consequence of numerous spinocerebellar ataxia mutations in β-III-spectrin.
Atang AE; Keller AR; Denha SA; Avery AW
bioRxiv; 2023 Apr; ():. PubMed ID: 36865188
[TBL] [Abstract][Full Text] [Related]
18. Ankyrin-R Links Kv3.3 to the Spectrin Cytoskeleton and Is Required for Purkinje Neuron Survival.
Stevens SR; van der Heijden ME; Ogawa Y; Lin T; Sillitoe RV; Rasband MN
J Neurosci; 2022 Jan; 42(1):2-15. PubMed ID: 34785580
[TBL] [Abstract][Full Text] [Related]
19. Infantile-onset spinocerebellar ataxia type 5 associated with a novel SPTBN2 mutation: A case report.
Mizuno T; Kashimada A; Nomura T; Moriyama K; Yokoyama H; Hasegawa S; Takagi M; Mizutani S
Brain Dev; 2019 Aug; 41(7):630-633. PubMed ID: 30898343
[TBL] [Abstract][Full Text] [Related]
20. Spectrin mutations in spinocerebellar ataxia (SCA).
Bauer P; Schöls L; Riess O
Bioessays; 2006 Aug; 28(8):785-7. PubMed ID: 16927298
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]