234 related articles for article (PubMed ID: 29084939)
21. Protein kinase C alpha trigger Ras and Raf-independent MEK/ERK activation for TPA-induced growth inhibition of human hepatoma cell HepG2.
Wen-Sheng W
Cancer Lett; 2006 Jul; 239(1):27-35. PubMed ID: 16169661
[TBL] [Abstract][Full Text] [Related]
22. Classical RAS proteins are not essential for paradoxical ERK activation induced by RAF inhibitors.
Lai LP; Fer N; Burgan W; Wall VE; Xu B; Soppet D; Esposito D; Nissley DV; McCormick F
Proc Natl Acad Sci U S A; 2022 Feb; 119(5):. PubMed ID: 35091470
[TBL] [Abstract][Full Text] [Related]
23. Involvement of Ras/Raf-1/ERK actions in the magnolol-induced upregulation of p21 and cell-cycle arrest in colon cancer cells.
Hsu YF; Lee TS; Lin SY; Hsu SP; Juan SH; Hsu YH; Zhong WB; Lee WS
Mol Carcinog; 2007 Apr; 46(4):275-83. PubMed ID: 17295239
[TBL] [Abstract][Full Text] [Related]
24. Inhibitors of Raf kinase activity block growth of thyroid cancer cells with RET/PTC or BRAF mutations in vitro and in vivo.
Ouyang B; Knauf JA; Smith EP; Zhang L; Ramsey T; Yusuff N; Batt D; Fagin JA
Clin Cancer Res; 2006 Mar; 12(6):1785-93. PubMed ID: 16551863
[TBL] [Abstract][Full Text] [Related]
25. Dimerization of the kinase ARAF promotes MAPK pathway activation and cell migration.
Mooz J; Oberoi-Khanuja TK; Harms GS; Wang W; Jaiswal BS; Seshagiri S; Tikkanen R; Rajalingam K
Sci Signal; 2014 Aug; 7(337):ra73. PubMed ID: 25097033
[TBL] [Abstract][Full Text] [Related]
26. CrkL plays a role in SDF-1-induced activation of the Raf-1/MEK/Erk pathway through Ras and Rac to mediate chemotactic signaling in hematopoietic cells.
Arai A; Aoki M; Weihua Y; Jin A; Miura O
Cell Signal; 2006 Dec; 18(12):2162-71. PubMed ID: 16781119
[TBL] [Abstract][Full Text] [Related]
27. Raf-1 kinase activation is uncoupled from downstream MEK/ERK pathway in cells treated with Src tyrosine kinase inhibitor PP2.
Lee M
Biochem Biophys Res Commun; 2006 Nov; 350(2):450-6. PubMed ID: 17010316
[TBL] [Abstract][Full Text] [Related]
28. Inhibitors that stabilize a closed RAF kinase domain conformation induce dimerization.
Lavoie H; Thevakumaran N; Gavory G; Li JJ; Padeganeh A; Guiral S; Duchaine J; Mao DY; Bouvier M; Sicheri F; Therrien M
Nat Chem Biol; 2013 Jul; 9(7):428-36. PubMed ID: 23685672
[TBL] [Abstract][Full Text] [Related]
29. ROS production induced by BRAF inhibitor treatment rewires metabolic processes affecting cell growth of melanoma cells.
Cesi G; Walbrecq G; Zimmer A; Kreis S; Haan C
Mol Cancer; 2017 Jun; 16(1):102. PubMed ID: 28595656
[TBL] [Abstract][Full Text] [Related]
30. RAF protein-serine/threonine kinases: structure and regulation.
Roskoski R
Biochem Biophys Res Commun; 2010 Aug; 399(3):313-7. PubMed ID: 20674547
[TBL] [Abstract][Full Text] [Related]
31. B-Raf and Raf-1 are regulated by distinct autoregulatory mechanisms.
Tran NH; Wu X; Frost JA
J Biol Chem; 2005 Apr; 280(16):16244-53. PubMed ID: 15710605
[TBL] [Abstract][Full Text] [Related]
32. Identification of radicicol as an inhibitor of in vivo Ras/Raf interaction with the yeast two-hybrid screening system.
Ki SW; Kasahara K; Kwon HJ; Eishima J; Takesako K; Cooper JA; Yoshida M; Horinouchi S
J Antibiot (Tokyo); 1998 Oct; 51(10):936-44. PubMed ID: 9917007
[TBL] [Abstract][Full Text] [Related]
33. Targeting the RAF-MEK-ERK pathway in cancer therapy.
Montagut C; Settleman J
Cancer Lett; 2009 Oct; 283(2):125-34. PubMed ID: 19217204
[TBL] [Abstract][Full Text] [Related]
34. SPRED1 Interferes with K-ras but Not H-ras Membrane Anchorage and Signaling.
Siljamäki E; Abankwa D
Mol Cell Biol; 2016 Oct; 36(20):2612-25. PubMed ID: 27503857
[TBL] [Abstract][Full Text] [Related]
35. Inhibition of RAF Isoforms and Active Dimers by LY3009120 Leads to Anti-tumor Activities in RAS or BRAF Mutant Cancers.
Peng SB; Henry JR; Kaufman MD; Lu WP; Smith BD; Vogeti S; Rutkoski TJ; Wise S; Chun L; Zhang Y; Van Horn RD; Yin T; Zhang X; Yadav V; Chen SH; Gong X; Ma X; Webster Y; Buchanan S; Mochalkin I; Huber L; Kays L; Donoho GP; Walgren J; McCann D; Patel P; Conti I; Plowman GD; Starling JJ; Flynn DL
Cancer Cell; 2015 Sep; 28(3):384-98. PubMed ID: 26343583
[TBL] [Abstract][Full Text] [Related]
36. Interferon-alpha2b reduces phosphorylation and activity of MEK and ERK through a Ras/Raf-independent mechanism.
Romerio F; Riva A; Zella D
Br J Cancer; 2000 Aug; 83(4):532-8. PubMed ID: 10945503
[TBL] [Abstract][Full Text] [Related]
37. Radicicol suppresses transformation and restores tropomyosin-2 expression in both ras- and MEK-transformed cells without inhibiting the Raf/MEK/ERK signaling cascade.
Kim PN; Jonasch E; Mosterman BC; Mier JW; Janssen RA
Cell Growth Differ; 2001 Nov; 12(11):543-50. PubMed ID: 11714635
[TBL] [Abstract][Full Text] [Related]
38. RAF inhibitors that evade paradoxical MAPK pathway activation.
Zhang C; Spevak W; Zhang Y; Burton EA; Ma Y; Habets G; Zhang J; Lin J; Ewing T; Matusow B; Tsang G; Marimuthu A; Cho H; Wu G; Wang W; Fong D; Nguyen H; Shi S; Womack P; Nespi M; Shellooe R; Carias H; Powell B; Light E; Sanftner L; Walters J; Tsai J; West BL; Visor G; Rezaei H; Lin PS; Nolop K; Ibrahim PN; Hirth P; Bollag G
Nature; 2015 Oct; 526(7574):583-6. PubMed ID: 26466569
[TBL] [Abstract][Full Text] [Related]
39. An Integrated Model of RAF Inhibitor Action Predicts Inhibitor Activity against Oncogenic BRAF Signaling.
Karoulia Z; Wu Y; Ahmed TA; Xin Q; Bollard J; Krepler C; Wu X; Zhang C; Bollag G; Herlyn M; Fagin JA; Lujambio A; Gavathiotis E; Poulikakos PI
Cancer Cell; 2016 Sep; 30(3):485-498. PubMed ID: 27523909
[TBL] [Abstract][Full Text] [Related]
40. Neuronal nitric oxide synthase-induced S-nitrosylation of H-Ras inhibits calcium ionophore-mediated extracellular-signal-regulated kinase activity.
Raines KW; Cao GL; Lee EK; Rosen GM; Shapiro P
Biochem J; 2006 Jul; 397(2):329-36. PubMed ID: 16569214
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]