221 related articles for article (PubMed ID: 29087414)
1. Discovery of novel BET inhibitors by drug repurposing of nitroxoline and its analogues.
Jiang H; Xing J; Wang C; Zhang H; Yue L; Wan X; Chen W; Ding H; Xie Y; Tao H; Chen Z; Jiang H; Chen K; Chen S; Zheng M; Zhang Y; Luo C
Org Biomol Chem; 2017 Nov; 15(44):9352-9361. PubMed ID: 29087414
[TBL] [Abstract][Full Text] [Related]
2. Selective inhibition mechanism of nitroxoline to the BET family: Insight from molecular simulations.
Zhu M; Song LT; Liu RR; Zhai HL; Meng YJ; Ren CL
Life Sci; 2021 Apr; 270():119141. PubMed ID: 33529672
[TBL] [Abstract][Full Text] [Related]
3. Rational design of 5-((1H-imidazol-1-yl)methyl)quinolin-8-ol derivatives as novel bromodomain-containing protein 4 inhibitors.
Xing J; Zhang R; Jiang X; Hu T; Wang X; Qiao G; Wang J; Yang F; Luo X; Chen K; Shen J; Luo C; Jiang H; Zheng M
Eur J Med Chem; 2019 Feb; 163():281-294. PubMed ID: 30529546
[TBL] [Abstract][Full Text] [Related]
4. Development and evaluation of a novel series of Nitroxoline-derived BET inhibitors with antitumor activity in renal cell carcinoma.
Chen W; Zhang H; Chen Z; Jiang H; Liao L; Fan S; Xing J; Xie Y; Chen S; Ding H; Chen K; Jiang H; Luo C; Zheng M; Yao Z; Huang Y; Zhang Y
Oncogenesis; 2018 Nov; 7(11):83. PubMed ID: 30385738
[TBL] [Abstract][Full Text] [Related]
5. Repurposing of nitroxoline as a potential anticancer agent against human prostate cancer: a crucial role on AMPK/mTOR signaling pathway and the interplay with Chk2 activation.
Chang WL; Hsu LC; Leu WJ; Chen CS; Guh JH
Oncotarget; 2015 Nov; 6(37):39806-20. PubMed ID: 26447757
[TBL] [Abstract][Full Text] [Related]
6. Rationally repurposed nitroxoline inhibits preclinical models of Epstein-Barr virus-associated lymphoproliferation.
Ibáñez de Garayo M; Liu W; Rondeau NC; Damoci CB; Miranda JJL
J Antibiot (Tokyo); 2021 Oct; 74(10):763-766. PubMed ID: 34163027
[TBL] [Abstract][Full Text] [Related]
7. Design, synthesis and biological evaluation of benzo[cd]indol-2(1H)-ones derivatives as BRD4 inhibitors.
Feng Y; Xiao S; Chen Y; Jiang H; Liu N; Luo C; Chen S; Chen H
Eur J Med Chem; 2018 May; 152():264-273. PubMed ID: 29730189
[TBL] [Abstract][Full Text] [Related]
8. Discovery of a series of dihydroquinoxalin-2(1H)-ones as selective BET inhibitors from a dual PLK1-BRD4 inhibitor.
Hu J; Wang Y; Li Y; Xu L; Cao D; Song S; Damaneh MS; Wang X; Meng T; Chen YL; Shen J; Miao Z; Xiong B
Eur J Med Chem; 2017 Sep; 137():176-195. PubMed ID: 28586718
[TBL] [Abstract][Full Text] [Related]
9. Nitroxoline induces apoptosis and slows glioma growth in vivo.
Lazovic J; Guo L; Nakashima J; Mirsadraei L; Yong W; Kim HJ; Ellingson B; Wu H; Pope WB
Neuro Oncol; 2015 Jan; 17(1):53-62. PubMed ID: 25074541
[TBL] [Abstract][Full Text] [Related]
10. Discovery of novel [1,2,4]triazolo[4,3-a]quinoxaline aminophenyl derivatives as BET inhibitors for cancer treatment.
Ali I; Lee J; Go A; Choi G; Lee K
Bioorg Med Chem Lett; 2017 Oct; 27(20):4606-4613. PubMed ID: 28939121
[TBL] [Abstract][Full Text] [Related]
11. Discovery of Benzo[cd]indol-2(1H)-ones as Potent and Specific BET Bromodomain Inhibitors: Structure-Based Virtual Screening, Optimization, and Biological Evaluation.
Xue X; Zhang Y; Liu Z; Song M; Xing Y; Xiang Q; Wang Z; Tu Z; Zhou Y; Ding K; Xu Y
J Med Chem; 2016 Feb; 59(4):1565-79. PubMed ID: 26731490
[TBL] [Abstract][Full Text] [Related]
12. Synthesis and evaluation of a large library of nitroxoline derivatives as pancreatic cancer antiproliferative agents.
Veschi S; Carradori S; De Lellis L; Florio R; Brocco D; Secci D; Guglielmi P; Spano M; Sobolev AP; Cama A
J Enzyme Inhib Med Chem; 2020 Dec; 35(1):1331-1344. PubMed ID: 32588672
[TBL] [Abstract][Full Text] [Related]
13. Discovery of novel BRD4 inhibitors by high-throughput screening, crystallography, and cell-based assays.
Sun Z; Zhang H; Chen Z; Xie Y; Jiang H; Chen L; Ding H; Zhang Y; Jiang H; Zheng M; Luo C
Bioorg Med Chem Lett; 2017 May; 27(9):2003-2009. PubMed ID: 28347667
[TBL] [Abstract][Full Text] [Related]
14. Cathepsin B inhibitors: Further exploration of the nitroxoline core.
Sosič I; Mitrović A; Ćurić H; Knez D; Brodnik Žugelj H; Štefane B; Kos J; Gobec S
Bioorg Med Chem Lett; 2018 Apr; 28(7):1239-1247. PubMed ID: 29503024
[TBL] [Abstract][Full Text] [Related]
15. Quinoline-based clioquinol and nitroxoline exhibit anticancer activity inducing FoxM1 inhibition in cholangiocarcinoma cells.
Chan-On W; Huyen NT; Songtawee N; Suwanjang W; Prachayasittikul S; Prachayasittikul V
Drug Des Devel Ther; 2015; 9():2033-47. PubMed ID: 25897210
[TBL] [Abstract][Full Text] [Related]
16. Effects of repurposed drug candidates nitroxoline and nelfinavir as single agents or in combination with erlotinib in pancreatic cancer cells.
Veschi S; De Lellis L; Florio R; Lanuti P; Massucci A; Tinari N; De Tursi M; di Sebastiano P; Marchisio M; Natoli C; Cama A
J Exp Clin Cancer Res; 2018 Sep; 37(1):236. PubMed ID: 30241558
[TBL] [Abstract][Full Text] [Related]
17. Discovery of Benzo[
Jiang F; Hu Q; Zhang Z; Li H; Li H; Zhang D; Li H; Ma Y; Xu J; Chen H; Cui Y; Zhi Y; Zhang Y; Xu J; Zhu J; Lu T; Chen Y
J Med Chem; 2019 Dec; 62(24):11080-11107. PubMed ID: 31789032
[TBL] [Abstract][Full Text] [Related]
18. Design, synthesis and biological evaluation of novel 4-phenylisoquinolinone BET bromodomain inhibitors.
Bennett MJ; Wu Y; Boloor A; Matuszkiewicz J; O'Connell SM; Shi L; Stansfield RK; Del Rosario JR; Veal JM; Hosfield DJ; Xu J; Kaldor SW; Stafford JA; Betancort JM
Bioorg Med Chem Lett; 2018 Jun; 28(10):1811-1816. PubMed ID: 29657099
[TBL] [Abstract][Full Text] [Related]
19. A new BET inhibitor, 171, inhibits tumor growth through cell proliferation inhibition more than apoptosis induction.
Damaneh MS; Hu JP; Huan XJ; Song SS; Tian CQ; Chen DQ; Meng T; Chen YL; Shen JK; Xiong B; Miao ZH; Wang YQ
Invest New Drugs; 2020 Jun; 38(3):700-713. PubMed ID: 31267379
[TBL] [Abstract][Full Text] [Related]
20. Structure investigation, enrichment analysis and structure-based repurposing of FDA-approved drugs as inhibitors of BET-BRD4.
Wakchaure P; Velayutham R; Roy KK
J Biomol Struct Dyn; 2019 Aug; 37(12):3048-3057. PubMed ID: 30079805
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
