248 related articles for article (PubMed ID: 29089037)
1. Revisiting atenolol as a low passive permeability marker.
Chen X; Slättengren T; de Lange ECM; Smith DE; Hammarlund-Udenaes M
Fluids Barriers CNS; 2017 Oct; 14(1):30. PubMed ID: 29089037
[TBL] [Abstract][Full Text] [Related]
2. Quantitative investigation of the brain-to-cerebrospinal fluid unbound drug concentration ratio under steady-state conditions in rats using a pharmacokinetic model and scaling factors for active efflux transporters.
Kodaira H; Kusuhara H; Fuse E; Ushiki J; Sugiyama Y
Drug Metab Dispos; 2014 Jun; 42(6):983-9. PubMed ID: 24644297
[TBL] [Abstract][Full Text] [Related]
3. Active Uptake of Oxycodone at Both the Blood-Cerebrospinal Fluid Barrier and The Blood-Brain Barrier without Sex Differences: A Rat Microdialysis Study.
Bällgren F; Hammarlund-Udenaes M; Loryan I
Pharm Res; 2023 Nov; 40(11):2715-2730. PubMed ID: 37610619
[TBL] [Abstract][Full Text] [Related]
4. Innovative in vitro method to predict rate and extent of drug delivery to the brain across the blood-brain barrier.
Mangas-Sanjuan V; González-Álvarez I; González-Álvarez M; Casabó VG; Bermejo M
Mol Pharm; 2013 Oct; 10(10):3822-31. PubMed ID: 23977999
[TBL] [Abstract][Full Text] [Related]
5. The use of intracerebral microdialysis to determine changes in blood-brain barrier transport characteristics.
de Lange EC; Hesselink MB; Danhof M; de Boer AG; Breimer DD
Pharm Res; 1995 Jan; 12(1):129-33. PubMed ID: 7724474
[TBL] [Abstract][Full Text] [Related]
6. In vivo blood-brain barrier transport of oxycodone in the rat: indications for active influx and implications for pharmacokinetics/pharmacodynamics.
Boström E; Simonsson US; Hammarlund-Udenaes M
Drug Metab Dispos; 2006 Sep; 34(9):1624-31. PubMed ID: 16763013
[TBL] [Abstract][Full Text] [Related]
7. Cocktail-Dosing Microdialysis Study to Simultaneously Assess Delivery of Multiple Organic-Cationic Drugs to the Brain.
Kitamura A; Okura T; Higuchi K; Deguchi Y
J Pharm Sci; 2016 Feb; 105(2):935-940. PubMed ID: 26554532
[TBL] [Abstract][Full Text] [Related]
8. Microdialysis evaluation of atomoxetine brain penetration and central nervous system pharmacokinetics in rats.
Kielbasa W; Kalvass JC; Stratford R
Drug Metab Dispos; 2009 Jan; 37(1):137-42. PubMed ID: 18936112
[TBL] [Abstract][Full Text] [Related]
9. Blood-brain barrier transport helps to explain discrepancies in in vivo potency between oxycodone and morphine.
Boström E; Hammarlund-Udenaes M; Simonsson US
Anesthesiology; 2008 Mar; 108(3):495-505. PubMed ID: 18292687
[TBL] [Abstract][Full Text] [Related]
10. Use of a physiologically based pharmacokinetic model to study the time to reach brain equilibrium: an experimental analysis of the role of blood-brain barrier permeability, plasma protein binding, and brain tissue binding.
Liu X; Smith BJ; Chen C; Callegari E; Becker SL; Chen X; Cianfrogna J; Doran AC; Doran SD; Gibbs JP; Hosea N; Liu J; Nelson FR; Szewc MA; Van Deusen J
J Pharmacol Exp Ther; 2005 Jun; 313(3):1254-62. PubMed ID: 15743928
[TBL] [Abstract][Full Text] [Related]
11. Blood-brain barrier transport and brain distribution of morphine-6-glucuronide in relation to the antinociceptive effect in rats--pharmacokinetic/pharmacodynamic modelling.
Bouw MR; Xie R; Tunblad K; Hammarlund-Udenaes M
Br J Pharmacol; 2001 Dec; 134(8):1796-804. PubMed ID: 11739257
[TBL] [Abstract][Full Text] [Related]
12. Effects of short-term portacaval anastomosis on the peripheral and brain disposition of the blood-brain barrier permeability marker sodium fluorescein in rats.
Shaik IH; Miah MK; Bickel U; Mehvar R
Brain Res; 2013 Sep; 1531():84-93. PubMed ID: 23916670
[TBL] [Abstract][Full Text] [Related]
13. Effect of transporter inhibition on the distribution of cefadroxil in rat brain.
Chen X; Loryan I; Payan M; Keep RF; Smith DE; Hammarlund-Udenaes M
Fluids Barriers CNS; 2014; 11(1):25. PubMed ID: 25414790
[TBL] [Abstract][Full Text] [Related]
14. Comparison of in vitro BBMEC permeability and in vivo CNS uptake by microdialysis sampling.
Hansen DK; Scott DO; Otis KW; Lunte SM
J Pharm Biomed Anal; 2002 Mar; 27(6):945-58. PubMed ID: 11836058
[TBL] [Abstract][Full Text] [Related]
15. Examining the Uptake of Central Nervous System Drugs and Candidates across the Blood-Brain Barrier.
Summerfield SG; Zhang Y; Liu H
J Pharmacol Exp Ther; 2016 Aug; 358(2):294-305. PubMed ID: 27194478
[TBL] [Abstract][Full Text] [Related]
16. Brain distribution of cetirizine enantiomers: comparison of three different tissue-to-plasma partition coefficients: K(p), K(p,u), and K(p,uu).
Gupta A; Chatelain P; Massingham R; Jonsson EN; Hammarlund-Udenaes M
Drug Metab Dispos; 2006 Feb; 34(2):318-23. PubMed ID: 16303872
[TBL] [Abstract][Full Text] [Related]
17. Probenecid-inhibitable efflux transport of valproic acid in the brain parenchymal cells of rabbits: a microdialysis study.
Scism JL; Powers KM; Artru AA; Lewis L; Shen DD
Brain Res; 2000 Nov; 884(1--2):77-86. PubMed ID: 11082489
[TBL] [Abstract][Full Text] [Related]
18. Investigation of utility of cerebrospinal fluid drug concentration as a surrogate for interstitial fluid concentration using microdialysis coupled with cisternal cerebrospinal fluid sampling in wild-type and Mdr1a(-/-) rats.
Nagaya Y; Nozaki Y; Takenaka O; Watari R; Kusano K; Yoshimura T; Kusuhara H
Drug Metab Pharmacokinet; 2016 Feb; 31(1):57-66. PubMed ID: 26830080
[TBL] [Abstract][Full Text] [Related]
19. The simultaneous estimation of the influx and efflux blood-brain barrier permeabilities of gabapentin using a microdialysis-pharmacokinetic approach.
Wang Y; Welty DF
Pharm Res; 1996 Mar; 13(3):398-403. PubMed ID: 8692732
[TBL] [Abstract][Full Text] [Related]
20. Investigation of the high partition of YM992, a novel antidepressant, in rat brain - in vitro and in vivo evidence for the high binding in brain and the high permeability at the BBB.
Mano Y; Higuchi S; Kamimura H
Biopharm Drug Dispos; 2002 Dec; 23(9):351-60. PubMed ID: 12469328
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]