96 related articles for article (PubMed ID: 29091454)
1. Electrochemical versus Enzymatic in Vitro Oxidations of 6-propyl-2-thiouracil: Identification, Detection, and Characterization of Metabolites.
Chipiso K; Simoyi RH
J Phys Chem B; 2017 Dec; 121(48):10749-10758. PubMed ID: 29091454
[TBL] [Abstract][Full Text] [Related]
2. P450-catalyzed vs. electrochemical oxidation of haloperidol studied by ultra-performance liquid chromatography/electrospray ionization mass spectrometry.
Mali'n TJ; Weidolf L; Castagnoli N; Jurva U
Rapid Commun Mass Spectrom; 2010 May; 24(9):1231-40. PubMed ID: 20391593
[TBL] [Abstract][Full Text] [Related]
3. Use of electrochemical oxidation and model peptides to study nucleophilic biological targets of reactive metabolites: the case of rimonabant.
Thorsell A; Isin EM; Jurva U
Chem Res Toxicol; 2014 Oct; 27(10):1808-20. PubMed ID: 25210840
[TBL] [Abstract][Full Text] [Related]
4. Direct protection against acetaminophen hepatotoxicity by propylthiouracil. In vivo and in vitro studies in rats and mice.
Yamada T; Ludwig S; Kuhlenkamp J; Kaplowitz N
J Clin Invest; 1981 Mar; 67(3):688-95. PubMed ID: 7204554
[TBL] [Abstract][Full Text] [Related]
5. Oxidation of propylthiouracil to reactive metabolites by activated neutrophils. Implications for agranulocytosis.
Waldhauser L; Uetrecht J
Drug Metab Dispos; 1991; 19(2):354-9. PubMed ID: 1676636
[TBL] [Abstract][Full Text] [Related]
6. Prediction of biotransformation products of the fungicide fluopyram by electrochemistry coupled online to liquid chromatography-mass spectrometry and comparison with in vitro microsomal assays.
Mekonnen TF; Panne U; Koch M
Anal Bioanal Chem; 2018 Apr; 410(10):2607-2617. PubMed ID: 29455286
[TBL] [Abstract][Full Text] [Related]
7. Activation of microsomal glutathione S-transferase and inhibition of cytochrome P450 1A1 activity as a model system for detecting protein alkylation by thiourea-containing compounds in rat liver microsomes.
Onderwater RC; Commandeur JN; Menge WM; Vermeulen NP
Chem Res Toxicol; 1999 May; 12(5):396-402. PubMed ID: 10328749
[TBL] [Abstract][Full Text] [Related]
8. Electrochemical generation of electrophilic drug metabolites: characterization of amodiaquine quinoneimine and cysteinyl conjugates by MS, IR, and NMR.
Jurva U; Holmén A; Grönberg G; Masimirembwa C; Weidolf L
Chem Res Toxicol; 2008 Apr; 21(4):928-35. PubMed ID: 18361508
[TBL] [Abstract][Full Text] [Related]
9. Identification of primary and sequential bioactivation pathways of carbamazepine in human liver microsomes using liquid chromatography/tandem mass spectrometry.
Bu HZ; Zhao P; Dalvie DK; Pool WF
Rapid Commun Mass Spectrom; 2007; 21(20):3317-22. PubMed ID: 17879390
[TBL] [Abstract][Full Text] [Related]
10. Thiolactone sulfoxides as new reactive metabolites acting as bis-electrophiles: implication in clopidogrel and prasugrel bioactivation.
Dansette PM; Levent D; Hessani A; Bertho G; Mansuy D
Chem Res Toxicol; 2013 May; 26(5):794-802. PubMed ID: 23527615
[TBL] [Abstract][Full Text] [Related]
11. Improved detection of reactive metabolites with a bromine-containing glutathione analog using mass defect and isotope pattern matching.
Leblanc A; Shiao TC; Roy R; Sleno L
Rapid Commun Mass Spectrom; 2010 May; 24(9):1241-50. PubMed ID: 20391594
[TBL] [Abstract][Full Text] [Related]
12. Bioactivation of glafenine by human liver microsomes and peroxidases: identification of electrophilic iminoquinone species and GSH conjugates.
Wen B; Moore DJ
Drug Metab Dispos; 2011 Sep; 39(9):1511-21. PubMed ID: 21628497
[TBL] [Abstract][Full Text] [Related]
13. Electrochemical oxidation of troglitazone: identification and characterization of the major reactive metabolite in liver microsomes.
Madsen KG; Grönberg G; Skonberg C; Jurva U; Hansen SH; Olsen J
Chem Res Toxicol; 2008 Oct; 21(10):2035-41. PubMed ID: 18788755
[TBL] [Abstract][Full Text] [Related]
14. Identification and quantification of potential metabolites of Gd-based contrast agents by electrochemistry/separations/mass spectrometry.
Telgmann L; Faber H; Jahn S; Melles D; Simon H; Sperling M; Karst U
J Chromatogr A; 2012 Jun; 1240():147-55. PubMed ID: 22525874
[TBL] [Abstract][Full Text] [Related]
15. Identification of a new reactive metabolite of pyrrolizidine alkaloid retrorsine: (3H-pyrrolizin-7-yl)methanol.
Fashe MM; Juvonen RO; Petsalo A; Rahnasto-Rilla M; Auriola S; Soininen P; Vepsäläinen J; Pasanen M
Chem Res Toxicol; 2014 Nov; 27(11):1950-7. PubMed ID: 25295702
[TBL] [Abstract][Full Text] [Related]
16. Metabolism of 35S- and 14C-labeled propylthiouracil in a model in vitro system containing thyroid peroxidase.
Taurog A; Dorris ML; Guziec FS; Uetrecht JP
Endocrinology; 1989 Jun; 124(6):3030-7. PubMed ID: 2656249
[TBL] [Abstract][Full Text] [Related]
17. Electrochemical Simulation of the Oxidative Capsaicin Metabolism.
Kreidl M; Rainer M; Bonn GK; Oberacher H
Chem Res Toxicol; 2021 Dec; 34(12):2522-2533. PubMed ID: 34879203
[TBL] [Abstract][Full Text] [Related]
18. Bioactivation of 4-methylphenol (p-cresol) via cytochrome P450-mediated aromatic oxidation in human liver microsomes.
Yan Z; Zhong HM; Maher N; Torres R; Leo GC; Caldwell GW; Huebert N
Drug Metab Dispos; 2005 Dec; 33(12):1867-76. PubMed ID: 16174805
[TBL] [Abstract][Full Text] [Related]
19. Liquid chromatography/nuclear magnetic resonance spectroscopy and liquid chromatography/mass spectrometry identification of novel metabolites of the multidrug resistance modulator LY335979 in rat bile and human liver microsomal incubations.
Ehlhardt WJ; Woodland JM; Baughman TM; Vandenbranden M; Wrighton SA; Kroin JS; Norman BH; Maple SR
Drug Metab Dispos; 1998 Jan; 26(1):42-51. PubMed ID: 9443851
[TBL] [Abstract][Full Text] [Related]
20. Evidence for the bioactivation of zomepirac and tolmetin by an oxidative pathway: identification of glutathione adducts in vitro in human liver microsomes and in vivo in rats.
Chen Q; Doss GA; Tung EC; Liu W; Tang YS; Braun MP; Didolkar V; Strauss JR; Wang RW; Stearns RA; Evans DC; Baillie TA; Tang W
Drug Metab Dispos; 2006 Jan; 34(1):145-51. PubMed ID: 16251255
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]