169 related articles for article (PubMed ID: 29103971)
1. Synthesis and biological evaluation of thiazole derivatives as GPR119 agonists.
Kim H; Cho SJ; Yoo M; Kang SK; Kim KR; Lee HH; Song JS; Rhee SD; Jung WH; Ahn JH; Jung JK; Jung KY
Bioorg Med Chem Lett; 2017 Dec; 27(23):5213-5220. PubMed ID: 29103971
[TBL] [Abstract][Full Text] [Related]
2. Synthesis and biological evaluation of thienopyrimidine derivatives as GPR119 agonists.
Jeon MK; Lee KM; Kim IH; Jang YK; Kang SK; Lee JM; Jung KY; Kumar JA; Rhee SD; Jung WH; Song JS; Bae MA; Kim KR; Ahn JH
Bioorg Med Chem Lett; 2014 Sep; 24(17):4281-5. PubMed ID: 25082125
[TBL] [Abstract][Full Text] [Related]
3. Design, synthesis, and biological evaluation of aryl N-methoxyamide derivatives as GPR119 agonists.
Jang YK; Lee KM; Jung KY; Kang SK; Pagire SH; Lee JM; Pagire HS; Kim KR; Bae MA; Lee H; Rhee SD; Ahn JH
Bioorg Med Chem Lett; 2017 Aug; 27(16):3909-3914. PubMed ID: 28666737
[TBL] [Abstract][Full Text] [Related]
4. Discovery and biological evaluation of novel G protein-coupled receptor 119 agonists for type 2 diabetes.
Zhou Y; Wang Y; Zhang L; Tang C; Feng B
Arch Pharm (Weinheim); 2019 Apr; 352(4):e1800267. PubMed ID: 30740769
[TBL] [Abstract][Full Text] [Related]
5. Design and synthesis of novel pyrimido[5,4-d]pyrimidine derivatives as GPR119 agonist for treatment of type 2 diabetes.
Fang Y; Xu J; Li Z; Yang Z; Xiong L; Jin Y; Wang Q; Xie S; Zhu W; Chang S
Bioorg Med Chem; 2018 Aug; 26(14):4080-4087. PubMed ID: 30100020
[TBL] [Abstract][Full Text] [Related]
6. Design, synthesis and Structure-activity relationship studies of new thiazole-based free fatty acid receptor 1 agonists for the treatment of type 2 diabetes.
Li Z; Qiu Q; Xu X; Wang X; Jiao L; Su X; Pan M; Huang W; Qian H
Eur J Med Chem; 2016 May; 113():246-57. PubMed ID: 26945112
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and evaluation of novel fused pyrimidine derivatives as GPR119 agonists.
Fang Y; Xiong L; Hu J; Zhang S; Xie S; Tu L; Wan Y; Jin Y; Li X; Hu S; Yang Z
Bioorg Chem; 2019 May; 86():103-111. PubMed ID: 30685641
[TBL] [Abstract][Full Text] [Related]
8. Design and synthesis of tetrahydropyridopyrimidine derivatives as dual GPR119 and DPP-4 modulators.
Fang Y; Zhang S; Wu W; Liu Y; Yang J; Li Y; Li M; Dong H; Jin Y; Liu R; Yang Z
Bioorg Chem; 2020 Jan; 94():103390. PubMed ID: 31662212
[TBL] [Abstract][Full Text] [Related]
9. The optimization of xanthine derivatives leading to HBK001 hydrochloride as a potent dual ligand targeting DPP-IV and GPR119.
Li G; Meng B; Yuan B; Huan Y; Zhou T; Jiang Q; Lei L; Sheng L; Wang W; Gong N; Lu Y; Ma C; Li Y; Shen Z; Huang H
Eur J Med Chem; 2020 Feb; 188():112017. PubMed ID: 31926470
[TBL] [Abstract][Full Text] [Related]
10. Design, synthesis, and biological evaluation of 2-(4-(methylsulfonyl)phenyl)pyridine derivatives as GPR119 agonists.
Zhou Y; Zhu X; Zhang L; Tang C; Feng B
Chem Biol Drug Des; 2019 Jan; 93(1):67-74. PubMed ID: 30120879
[TBL] [Abstract][Full Text] [Related]
11. Design, synthesis and biological evaluation of novel 7-azaspiro[3.5]nonane derivatives as GPR119 agonists.
Matsuda D; Kawamura M; Kobashi Y; Shiozawa F; Suga Y; Fusegi K; Nishimoto S; Kimura K; Miyoshi M; Takayama N; Kakinuma H; Ohtake N
Bioorg Med Chem; 2018 May; 26(8):1832-1847. PubMed ID: 29486951
[TBL] [Abstract][Full Text] [Related]
12. Design and synthesis of novel and potent GPR119 agonists with a spirocyclic structure.
Harada K; Mizukami J; Kadowaki S; Matsuda I; Watanabe T; Oe Y; Kodama Y; Aoki K; Suwa K; Fukuda S; Yata S; Inaba T
Bioorg Med Chem Lett; 2018 Apr; 28(7):1228-1233. PubMed ID: 29519733
[TBL] [Abstract][Full Text] [Related]
13. Synthesis and structure-activity relationship of fused-pyrimidine derivatives as a series of novel GPR119 agonists.
Negoro K; Yonetoku Y; Moritomo A; Hayakawa M; Iikubo K; Yoshida S; Takeuchi M; Ohta M
Bioorg Med Chem; 2012 Nov; 20(21):6442-51. PubMed ID: 23010456
[TBL] [Abstract][Full Text] [Related]
14. Structure-based optimization of free fatty acid receptor 1 agonists bearing thiazole scaffold.
Li Z; Xu X; Hou J; Wang S; Jiang H; Zhang L
Bioorg Chem; 2018 Apr; 77():429-435. PubMed ID: 29433092
[TBL] [Abstract][Full Text] [Related]
15. Discovery of a novel series of indolinylpyrimidine-based GPR119 agonists: Elimination of ether-a-go-go-related gene liability using a hydrogen bond acceptor-focused approach.
Kamaura M; Kubo O; Sugimoto H; Noguchi N; Miyashita H; Abe S; Matsuda K; Tsujihata Y; Odani T; Iwasaki S; Murata T; Sato K
Bioorg Med Chem; 2021 Mar; 34():116034. PubMed ID: 33548803
[TBL] [Abstract][Full Text] [Related]
16. Discovery of pyrazolo[3,4-d]pyrimidine derivatives as GPR119 agonists.
Gillespie P; Goodnow RA; Saha G; Bose G; Moulik K; Zwingelstein C; Myers M; Conde-Knape K; Pietranico-Cole S; So SS
Bioorg Med Chem Lett; 2014 Feb; 24(3):949-53. PubMed ID: 24412066
[TBL] [Abstract][Full Text] [Related]
17. Discovery and optimization of N-(3-(1,3-dioxo-2,3-dihydro-1H-pyrrolo[3,4-c]pyridin-4-yloxy)phenyl)benzenesulfonamides as novel GPR119 agonists.
Yu M; Ken Zhang J; Wang Y; Zhu J; Kayser F; Medina JC; Siegler K; Conn M; Shan B; Grillo MP; Coward P; Jim Liu J
Bioorg Med Chem Lett; 2014 Jan; 24(1):156-60. PubMed ID: 24332491
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and biological evaluation of 1, 2, 4-oxadiazole derivatives as novel GPR119 agonists.
Fu S; Xiang W; Chen J; Ma L; Chen L
Chem Biol Drug Des; 2017 May; 89(5):815-819. PubMed ID: 27779815
[TBL] [Abstract][Full Text] [Related]
19. GPR119: a promising target for nonalcoholic fatty liver disease.
Yang JW; Kim HS; Im JH; Kim JW; Jun DW; Lim SC; Lee K; Choi JM; Kim SK; Kang KW
FASEB J; 2016 Jan; 30(1):324-35. PubMed ID: 26399788
[TBL] [Abstract][Full Text] [Related]
20. Discovery and biological evaluation of novel 4-amino-2-phenylpyrimidine derivatives as potent and orally active GPR119 agonists.
Negoro K; Yonetoku Y; Misawa-Mukai H; Hamaguchi W; Maruyama T; Yoshida S; Takeuchi M; Ohta M
Bioorg Med Chem; 2012 Sep; 20(17):5235-46. PubMed ID: 22836190
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
