BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

450 related articles for article (PubMed ID: 29106038)

  • 1. The physical approximation of APP and BACE-1: A key event in alzheimer's disease pathogenesis.
    Sun J; Roy S
    Dev Neurobiol; 2018 Mar; 78(3):340-347. PubMed ID: 29106038
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Amyloid precursor protein compartmentalization restricts beta-amyloid production: therapeutic targets based on BACE compartmentalization.
    Gandhi S; Refolo LM; Sambamurti K
    J Mol Neurosci; 2004; 24(1):137-43. PubMed ID: 15314262
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Intracellular trafficking of the β-secretase and processing of amyloid precursor protein.
    Chia PZ; Gleeson PA
    IUBMB Life; 2011 Sep; 63(9):721-9. PubMed ID: 21834057
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Retromer regulates postendocytic sorting of β-secretase in polarized Madin-Darby canine kidney cells.
    Cuartero Y; Mellado M; Capell A; Alvarez-Dolado M; Verges M
    Traffic; 2012 Oct; 13(10):1393-410. PubMed ID: 22758778
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cellular Trafficking of Amyloid Precursor Protein in Amyloidogenesis Physiological and Pathological Significance.
    Mañucat-Tan NB; Saadipour K; Wang YJ; Bobrovskaya L; Zhou XF
    Mol Neurobiol; 2019 Feb; 56(2):812-830. PubMed ID: 29797184
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Visualizing APP and BACE-1 approximation in neurons yields insight into the amyloidogenic pathway.
    Das U; Wang L; Ganguly A; Saikia JM; Wagner SL; Koo EH; Roy S
    Nat Neurosci; 2016 Jan; 19(1):55-64. PubMed ID: 26642089
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Interaction of the cytosolic domains of sorLA/LR11 with the amyloid precursor protein (APP) and beta-secretase beta-site APP-cleaving enzyme.
    Spoelgen R; von Arnim CA; Thomas AV; Peltan ID; Koker M; Deng A; Irizarry MC; Andersen OM; Willnow TE; Hyman BT
    J Neurosci; 2006 Jan; 26(2):418-28. PubMed ID: 16407538
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Retention in endoplasmic reticulum 1 (RER1) modulates amyloid-β (Aβ) production by altering trafficking of γ-secretase and amyloid precursor protein (APP).
    Park HJ; Shabashvili D; Nekorchuk MD; Shyqyriu E; Jung JI; Ladd TB; Moore BD; Felsenstein KM; Golde TE; Kim SH
    J Biol Chem; 2012 Nov; 287(48):40629-40. PubMed ID: 23043097
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Activity-induced convergence of APP and BACE-1 in acidic microdomains via an endocytosis-dependent pathway.
    Das U; Scott DA; Ganguly A; Koo EH; Tang Y; Roy S
    Neuron; 2013 Aug; 79(3):447-60. PubMed ID: 23931995
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Oral administration of a potent and selective non-peptidic BACE-1 inhibitor decreases beta-cleavage of amyloid precursor protein and amyloid-beta production in vivo.
    Hussain I; Hawkins J; Harrison D; Hille C; Wayne G; Cutler L; Buck T; Walter D; Demont E; Howes C; Naylor A; Jeffrey P; Gonzalez MI; Dingwall C; Michel A; Redshaw S; Davis JB
    J Neurochem; 2007 Feb; 100(3):802-9. PubMed ID: 17156133
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dysregulation of intracellular trafficking and endosomal sorting in Alzheimer's disease: controversies and unanswered questions.
    Toh WH; Gleeson PA
    Biochem J; 2016 Jul; 473(14):1977-93. PubMed ID: 27407168
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Gleevec shifts APP processing from a β-cleavage to a nonamyloidogenic cleavage.
    Netzer WJ; Bettayeb K; Sinha SC; Flajolet M; Greengard P; Bustos V
    Proc Natl Acad Sci U S A; 2017 Feb; 114(6):1389-1394. PubMed ID: 28115709
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Proamyloidogenic effects of membrane type 1 matrix metalloproteinase involve MMP-2 and BACE-1 activities, and the modulation of APP trafficking.
    Paumier JM; Py NA; García-González L; Bernard A; Stephan D; Louis L; Checler F; Khrestchatisky M; Baranger K; Rivera S
    FASEB J; 2019 Feb; 33(2):2910-2927. PubMed ID: 30332299
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.
    Deng Y; Wang Z; Wang R; Zhang X; Zhang S; Wu Y; Staufenbiel M; Cai F; Song W
    Eur J Neurosci; 2013 Jun; 37(12):1962-9. PubMed ID: 23773065
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Beta-secretase processing of the Alzheimer's amyloid protein precursor (APP).
    Marlow L; Cain M; Pappolla MA; Sambamurti K
    J Mol Neurosci; 2003; 20(3):233-9. PubMed ID: 14501002
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The role of TMP21 in trafficking and amyloid-β precursor protein (APP) processing in Alzheimer's disease.
    Bromley-Brits K; Song W
    Curr Alzheimer Res; 2012 May; 9(4):411-24. PubMed ID: 22299712
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Failure of the interaction between presenilin 1 and the substrate of gamma-secretase to produce Abeta in insect cells.
    Pitsi D; Kienlen-Campard P; Octave JN
    J Neurochem; 2002 Oct; 83(2):390-9. PubMed ID: 12423249
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Proteolytic processing of the Alzheimer's disease amyloid precursor protein in brain and platelets.
    Evin G; Zhu A; Holsinger RM; Masters CL; Li QX
    J Neurosci Res; 2003 Nov; 74(3):386-92. PubMed ID: 14598315
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Trafficking and proteolytic processing of amyloid precursor protein and secretases in Alzheimer's disease development: An up-to-date review.
    Yuksel M; Tacal O
    Eur J Pharmacol; 2019 Aug; 856():172415. PubMed ID: 31132354
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Retromers in Alzheimer's disease.
    Siegenthaler BM; Rajendran L
    Neurodegener Dis; 2012; 10(1-4):116-21. PubMed ID: 22398391
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.