178 related articles for article (PubMed ID: 29116477)
1. 4EGI-1 represses cap-dependent translation and regulates genome-wide translation in malignant pleural mesothelioma.
De A; Jacobson BA; Peterson MS; Jay-Dixon J; Kratzke MG; Sadiq AA; Patel MR; Kratzke RA
Invest New Drugs; 2018 Apr; 36(2):217-229. PubMed ID: 29116477
[TBL] [Abstract][Full Text] [Related]
2. The eIF4E/eIF4G interaction inhibitor 4EGI-1 augments TRAIL-mediated apoptosis through c-FLIP Down-regulation and DR5 induction independent of inhibition of cap-dependent protein translation.
Fan S; Li Y; Yue P; Khuri FR; Sun SY
Neoplasia; 2010 Apr; 12(4):346-56. PubMed ID: 20360945
[TBL] [Abstract][Full Text] [Related]
3. Targeting eukaryotic translation in mesothelioma cells with an eIF4E-specific antisense oligonucleotide.
Jacobson BA; Thumma SC; Jay-Dixon J; Patel MR; Dubear Kroening K; Kratzke MG; Etchison RG; Konicek BW; Graff JR; Kratzke RA
PLoS One; 2013; 8(11):e81669. PubMed ID: 24260583
[TBL] [Abstract][Full Text] [Related]
4. Translation initiation complex eIF4F is a therapeutic target for dual mTOR kinase inhibitors in non-Hodgkin lymphoma.
Demosthenous C; Han JJ; Stenson MJ; Maurer MJ; Wellik LE; Link B; Hege K; Dogan A; Sotomayor E; Witzig T; Gupta M
Oncotarget; 2015 Apr; 6(11):9488-501. PubMed ID: 25839159
[TBL] [Abstract][Full Text] [Related]
5. Activated 4E-BP1 represses tumourigenesis and IGF-I-mediated activation of the eIF4F complex in mesothelioma.
Jacobson BA; De A; Kratzke MG; Patel MR; Jay-Dixon J; Whitson BA; Sadiq AA; Bitterman PB; Polunovsky VA; Kratzke RA
Br J Cancer; 2009 Aug; 101(3):424-31. PubMed ID: 19603014
[TBL] [Abstract][Full Text] [Related]
6. 4EGI-1 induces apoptosis and enhances radiotherapy sensitivity in nasopharyngeal carcinoma cells via DR5 induction on 4E-BP1 dephosphorylation.
Wang W; Li J; Wen Q; Luo J; Chu S; Chen L; Qing Z; Xie G; Xu L; Alnemah MM; Li M; Fan S; Zhang H
Oncotarget; 2016 Apr; 7(16):21728-41. PubMed ID: 26942880
[TBL] [Abstract][Full Text] [Related]
7. Anti-Cancer Effect of Cap-Translation Inhibitor 4EGI-1 in Human Glioma U87 Cells: Involvement of Mitochondrial Dysfunction and ER Stress.
Wu M; Zhang C; Li XJ; Liu Q; Wanggou S
Cell Physiol Biochem; 2016; 40(5):1013-1028. PubMed ID: 27941351
[TBL] [Abstract][Full Text] [Related]
8. The synergistic inhibition of breast cancer proliferation by combined treatment with 4EGI-1 and MK2206.
Wang H; Huang F; Wang J; Wang P; Lv W; Hong L; Li S; Zhou J
Cell Cycle; 2015; 14(2):232-42. PubMed ID: 25607647
[TBL] [Abstract][Full Text] [Related]
9. SUMO-2 promotes mRNA translation by enhancing interaction between eIF4E and eIF4G.
Chen LZ; Li XY; Huang H; Xing W; Guo W; He J; Sun ZY; Luo AX; Liang HP; Hu J; Wang ZG; Xu YS; Xu X
PLoS One; 2014; 9(6):e100457. PubMed ID: 24971752
[TBL] [Abstract][Full Text] [Related]
10. Small-molecule inhibition of the interaction between the translation initiation factors eIF4E and eIF4G.
Moerke NJ; Aktas H; Chen H; Cantel S; Reibarkh MY; Fahmy A; Gross JD; Degterev A; Yuan J; Chorev M; Halperin JA; Wagner G
Cell; 2007 Jan; 128(2):257-67. PubMed ID: 17254965
[TBL] [Abstract][Full Text] [Related]
11. Vesicular stomatitis virus infection alters the eIF4F translation initiation complex and causes dephosphorylation of the eIF4E binding protein 4E-BP1.
Connor JH; Lyles DS
J Virol; 2002 Oct; 76(20):10177-87. PubMed ID: 12239292
[TBL] [Abstract][Full Text] [Related]
12. Protein phosphatase 2A negatively regulates eukaryotic initiation factor 4E phosphorylation and eIF4F assembly through direct dephosphorylation of Mnk and eIF4E.
Li Y; Yue P; Deng X; Ueda T; Fukunaga R; Khuri FR; Sun SY
Neoplasia; 2010 Oct; 12(10):848-55. PubMed ID: 20927323
[TBL] [Abstract][Full Text] [Related]
13. 3-substituted indazoles as configurationally locked 4EGI-1 mimetics and inhibitors of the eIF4E/eIF4G interaction.
Yefidoff-Freedman R; Chen T; Sahoo R; Chen L; Wagner G; Halperin JA; Aktas BH; Chorev M
Chembiochem; 2014 Mar; 15(4):595-611. PubMed ID: 24458973
[TBL] [Abstract][Full Text] [Related]
14. Molecular mechanism of the dual activity of 4EGI-1: Dissociating eIF4G from eIF4E but stabilizing the binding of unphosphorylated 4E-BP1.
Sekiyama N; Arthanari H; Papadopoulos E; Rodriguez-Mias RA; Wagner G; Léger-Abraham M
Proc Natl Acad Sci U S A; 2015 Jul; 112(30):E4036-45. PubMed ID: 26170285
[TBL] [Abstract][Full Text] [Related]
15. Inhibition of Mitogen-activated Protein Kinase (MAPK)-interacting Kinase (MNK) Preferentially Affects Translation of mRNAs Containing Both a 5'-Terminal Cap and Hairpin.
Korneeva NL; Song A; Gram H; Edens MA; Rhoads RE
J Biol Chem; 2016 Feb; 291(7):3455-67. PubMed ID: 26668315
[TBL] [Abstract][Full Text] [Related]
16. Hepatitis C virus NS5A binds to the mRNA cap-binding eukaryotic translation initiation 4F (eIF4F) complex and up-regulates host translation initiation machinery through eIF4E-binding protein 1 inactivation.
George A; Panda S; Kudmulwar D; Chhatbar SP; Nayak SC; Krishnan HH
J Biol Chem; 2012 Feb; 287(7):5042-58. PubMed ID: 22184107
[TBL] [Abstract][Full Text] [Related]
17. Structure of the eukaryotic translation initiation factor eIF4E in complex with 4EGI-1 reveals an allosteric mechanism for dissociating eIF4G.
Papadopoulos E; Jenni S; Kabha E; Takrouri KJ; Yi T; Salvi N; Luna RE; Gavathiotis E; Mahalingam P; Arthanari H; Rodriguez-Mias R; Yefidoff-Freedman R; Aktas BH; Chorev M; Halperin JA; Wagner G
Proc Natl Acad Sci U S A; 2014 Aug; 111(31):E3187-95. PubMed ID: 25049413
[TBL] [Abstract][Full Text] [Related]
18. Mitosis-related phosphorylation of the eukaryotic translation suppressor 4E-BP1 and its interaction with eukaryotic translation initiation factor 4E (eIF4E).
Sun R; Cheng E; Velásquez C; Chang Y; Moore PS
J Biol Chem; 2019 Aug; 294(31):11840-11852. PubMed ID: 31201269
[TBL] [Abstract][Full Text] [Related]
19. Cap-dependent mRNA translation and the ubiquitin-proteasome system cooperate to promote ERBB2-dependent esophageal cancer phenotype.
Issaenko OA; Bitterman PB; Polunovsky VA; Dahlberg PS
Cancer Gene Ther; 2012 Sep; 19(9):609-18. PubMed ID: 22767218
[TBL] [Abstract][Full Text] [Related]
20. Repressor binding to a dorsal regulatory site traps human eIF4E in a high cap-affinity state.
Ptushkina M; von der Haar T; Karim MM; Hughes JM; McCarthy JE
EMBO J; 1999 Jul; 18(14):4068-75. PubMed ID: 10406811
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
