143 related articles for article (PubMed ID: 29118936)
1. Regulation of HSVtk gene by endogenous microRNA-122a in liver cell lines as suicide gene therapy.
Ghanbari M; Saberfar E; Goodarzi Z; Lashini H; Ghanbari S; Karamimanesh M; Baesi K
Gastroenterol Hepatol Bed Bench; 2017; 10(3):202-207. PubMed ID: 29118936
[TBL] [Abstract][Full Text] [Related]
2. miR-122a-Regulated Expression of a Suicide Gene Prevents Hepatotoxicity Without Altering Antitumor Effects in Suicide Gene Therapy.
Suzuki T; Sakurai F; Nakamura SI; Kouyama E; Kawabata K; Kondoh M; Yagi K; Mizuguchi H
Mol Ther; 2008 Oct; 16(10):1719-1726. PubMed ID: 28189004
[TBL] [Abstract][Full Text] [Related]
3. miR-122a-regulated expression of a suicide gene prevents hepatotoxicity without altering antitumor effects in suicide gene therapy.
Suzuki T; Sakurai F; Nakamura S; Kouyama E; Kawabata K; Kondoh M; Yagi K; Mizuguchi H
Mol Ther; 2008 Oct; 16(10):1719-26. PubMed ID: 18665157
[TBL] [Abstract][Full Text] [Related]
4. Evaluation of miR-122-regulated suicide gene therapy for hepatocellular carcinoma in an orthotopic mouse model.
Wang G; Dong X; Tian W; Lu Y; Hu J; Liu Y; Yuchi J; Wu X
Chin J Cancer Res; 2013 Dec; 25(6):646-55. PubMed ID: 24385691
[TBL] [Abstract][Full Text] [Related]
5. Transduction Properties of an Adenovirus Vector Containing Sequences Complementary to a Liver-Specific microRNA, miR-122a, in the 3'-Untranslated Region of the E4 Gene in Human Hepatocytes from Chimeric Mice with Humanized Liver.
Sakurai F; Tsukamoto T; Ono R; Nishimae F; Shiota A; Iizuka S; Shimizu K; Sakai E; Ishida Y; Tateno C; Chayama K; Mizuguchi H
Biol Pharm Bull; 2021; 44(10):1506-1513. PubMed ID: 34602559
[TBL] [Abstract][Full Text] [Related]
6. HSVtk/GCV system on hepatoma carcinoma cells: Construction of the plasmid pcDNA3.1‑pAFP-TK and targeted killing effect.
Li YF; Yuan YY; Zhang YM; Zhao N; Zhang Q; Meng FX; Gao RP; Yu BF; Zhang YH; Guo R; Wang HL; Xie J; Xu J; Qin Q; Dong XS
Mol Med Rep; 2017 Jul; 16(1):764-772. PubMed ID: 28560395
[TBL] [Abstract][Full Text] [Related]
7. Construction of plasmid vector pAFP-HSVtk-IRES2-EGFP and its effect on the cytotoxicity of ganciclovir to hepatocellular carcinoma.
Lai Z; Qin Q; Yu B; Xie J; Gao R; Zhang T; Li C; Niu K; Xu J
Chin Med J (Engl); 2014; 127(12):2337-41. PubMed ID: 24931253
[TBL] [Abstract][Full Text] [Related]
8. HSV vector cytotoxicity is inversely correlated with effective TK/GCV suicide gene therapy of rat gliosarcoma.
Moriuchi S; Krisky DM; Marconi PC; Tamura M; Shimizu K; Yoshimine T; Cohen JB; Glorioso JC
Gene Ther; 2000 Sep; 7(17):1483-90. PubMed ID: 11001368
[TBL] [Abstract][Full Text] [Related]
9. Enhanced antitumor effect and reduced vector dissemination with fiber-modified adenovirus vectors expressing herpes simplex virus thymidine kinase.
Mizuguchi H; Hayakawa T
Cancer Gene Ther; 2002 Mar; 9(3):236-42. PubMed ID: 11896439
[TBL] [Abstract][Full Text] [Related]
10. Cancer-specific targeting of an adenovirus-delivered herpes simplex virus thymidine kinase suicide gene using translational control.
Mathis JM; Williams BJ; Sibley DA; Carroll JL; Li J; Odaka Y; Barlow S; Nathan CO; Li BD; DeBenedetti A
J Gene Med; 2006 Sep; 8(9):1105-20. PubMed ID: 16802401
[TBL] [Abstract][Full Text] [Related]
11. Suicide gene therapy of human breast cancer in SCID mice model by the regulation of Tet-On.
Hu WX; Zeng ZJ; Luo SQ; Chen Q
Chin Med J (Engl); 2004 Mar; 117(3):434-9. PubMed ID: 15043787
[TBL] [Abstract][Full Text] [Related]
12. [Development and Characterization of a Novel Adenovirus Vector Exhibiting MicroRNA-mediated Suppression of the Leaky Expression of Adenovirus Genes].
Shimizu K
Yakugaku Zasshi; 2015; 135(12):1349-56. PubMed ID: 26632150
[TBL] [Abstract][Full Text] [Related]
13. Evaluation of an E1E4-deleted adenovirus expressing the herpes simplex thymidine kinase suicide gene in cancer gene therapy.
Lanuti M; Gao GP; Force SD; Chang MY; El Kouri C; Amin KM; Hughes JV; Wilson JM; Kaiser LR; Albelda SM
Hum Gene Ther; 1999 Feb; 10(3):463-75. PubMed ID: 10048398
[TBL] [Abstract][Full Text] [Related]
14. Tumor-specific in vivo transfection with HSV-1 thymidine kinase gene using a Sindbis viral vector as a basis for prodrug ganciclovir activation and PET.
Tseng JC; Zanzonico PB; Levin B; Finn R; Larson SM; Meruelo D
J Nucl Med; 2006 Jul; 47(7):1136-43. PubMed ID: 16818948
[TBL] [Abstract][Full Text] [Related]
15. Suppression of hepatitis C virus replicon by adenovirus vector-mediated expression of tough decoy RNA against miR-122a.
Sakurai F; Furukawa N; Higuchi M; Okamoto S; Ono K; Yoshida T; Kondoh M; Yagi K; Sakamoto N; Katayama K; Mizuguchi H
Virus Res; 2012 May; 165(2):214-8. PubMed ID: 22342424
[TBL] [Abstract][Full Text] [Related]
16. Suppression of leaky expression of adenovirus genes by insertion of microRNA-targeted sequences in the replication-incompetent adenovirus vector genome.
Shimizu K; Sakurai F; Tomita K; Nagamoto Y; Nakamura S; Katayama K; Tachibana M; Kawabata K; Mizuguchi H
Mol Ther Methods Clin Dev; 2014; 1():14035. PubMed ID: 26015975
[TBL] [Abstract][Full Text] [Related]
17. Further reduction in adenovirus vector-mediated liver transduction without largely affecting transgene expression in target organ by exploiting microrna-mediated regulation and the Cre-loxP recombination system.
Bennett D; Sakurai F; Shimizu K; Matsui H; Tomita K; Suzuki T; Katayama K; Kawabata K; Mizuguchi H
Mol Pharm; 2012 Dec; 9(12):3452-63. PubMed ID: 23127182
[TBL] [Abstract][Full Text] [Related]
18. Transcriptional targeting of RGD fiber-mutant adenovirus vectors can improve the safety of suicide gene therapy for murine melanoma.
Okada Y; Okada N; Mizuguchi H; Hayakawa T; Nakagawa S; Mayumi T
Cancer Gene Ther; 2005 Jul; 12(7):608-16. PubMed ID: 15746944
[TBL] [Abstract][Full Text] [Related]
19. [The effect of lentivirus-mediated suicide gene therapy on lens epithelial cells].
Yang J; Lu Y; Guo LH; Liu TJ; Mo XF
Zhonghua Yan Ke Za Zhi; 2007 Sep; 43(9):810-6. PubMed ID: 18070527
[TBL] [Abstract][Full Text] [Related]
20. Adenovirus E1a protein enhances the cytotoxic effects of the herpes thymidine kinase-ganciclovir system.
Parada C; Hernández Losa J; Guinea J; Sánchez-Arévalo V; Fernández Soria V; Alvarez-Vallina L; Sánchez-Prieto R; Ramón y Cajal S
Cancer Gene Ther; 2003 Feb; 10(2):152-60. PubMed ID: 12536204
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
