BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

202 related articles for article (PubMed ID: 29119968)

  • 1. Time-dependent pharmacokinetics of dexamethasone and its efficacy in human breast cancer xenograft mice: a semi-mechanism-based pharmacokinetic/pharmacodynamic model.
    Li J; Chen R; Yao QY; Liu SJ; Tian XY; Hao CY; Lu W; Zhou TY
    Acta Pharmacol Sin; 2018 Mar; 39(3):472-481. PubMed ID: 29119968
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Preclinical PK/PD model for the combinatorial use of dexamethasone and sulpiride in the treatment of breast cancer.
    Yao QY; Li J; Chen R; Yao Y; Xue JS; Chen WJ; Lu W; Zhou TY
    Acta Pharmacol Sin; 2019 Dec; 40(12):1596-1602. PubMed ID: 31165782
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Semi-Mechanism-Based Pharmacokinetic/Pharmacodynamic Model for the Combination Use of Dexamethasone and Gemcitabine in Breast Cancer.
    Yuan Y; Zhou X; Ren Y; Zhou S; Wang L; Ji S; Hua M; Li L; Lu W; Zhou T
    J Pharm Sci; 2015 Dec; 104(12):4399-4408. PubMed ID: 26344053
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A mechanism-based pharmacokinetic/pharmacodynamic model for CYP3A1/2 induction by dexamethasone in rats.
    Li L; Li ZQ; Deng CH; Ning MR; Li HQ; Bi SS; Zhou TY; Lu W
    Acta Pharmacol Sin; 2012 Jan; 33(1):127-36. PubMed ID: 22212433
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pharmacokinetic/Pharmacodynamic Modeling of the Anti-Cancer Effect of Dexamethasone in Pancreatic Cancer Xenografts and Anticipation of Human Efficacious Doses.
    Yao Y; Yao Q; Fu Y; Tian X; An Q; Yang L; Su H; Lu W; Hao C; Zhou T
    J Pharm Sci; 2020 Feb; 109(2):1169-1177. PubMed ID: 31655033
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Bridging the gap between preclinical and clinical studies using pharmacokinetic-pharmacodynamic modeling: an analysis of GDC-0973, a MEK inhibitor.
    Wong H; Vernillet L; Peterson A; Ware JA; Lee L; Martini JF; Yu P; Li C; Del Rosario G; Choo EF; Hoeflich KP; Shi Y; Aftab BT; Aoyama R; Lam ST; Belvin M; Prescott J
    Clin Cancer Res; 2012 Jun; 18(11):3090-9. PubMed ID: 22496205
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Population pharmacodynamic modeling of intramuscular and oral dexamethasone and betamethasone effects on six biomarkers with circadian complexities in Indian women.
    Krzyzanski W; Milad MA; Jobe AH; Peppard T; Bies RR; Jusko WJ
    J Pharmacokinet Pharmacodyn; 2021 Jun; 48(3):411-438. PubMed ID: 33954911
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Human microdosing and mice xenograft data of AGM-130 applied to estimate efficacious doses in patients.
    Park WS; Park GJ; Han S; Ban S; Park MY; Kim SH; Kim SM; Kim YC; Kim HS; Shin YG; Yim DS
    Cancer Chemother Pharmacol; 2017 Aug; 80(2):363-369. PubMed ID: 28660432
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Preclinical pharmacokinetic/pharmacodynamic/efficacy relationships for alisertib, an investigational small-molecule inhibitor of Aurora A kinase.
    Palani S; Patel M; Huck J; Zhang M; Balani SK; Yang J; Chen S; Mettetal J; Manfredi M; Shyu WC; Ecsedy JA; Chakravarty A
    Cancer Chemother Pharmacol; 2013 Dec; 72(6):1255-64. PubMed ID: 24101146
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Preclinical pharmacokinetics, disposition, and translational pharmacokinetic/pharmacodynamic modeling of savolitinib, a novel selective cMet inhibitor.
    Gu Y; Sai Y; Wang J; Yu M; Wang G; Zhang L; Ren H; Fan S; Ren Y; Qing W; Su W
    Eur J Pharm Sci; 2019 Aug; 136():104938. PubMed ID: 31132401
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Physiologically Based Pharmacokinetics of Dexamethasone in Rats.
    Song D; Sun L; DuBois DC; Almon RR; Meng S; Jusko WJ
    Drug Metab Dispos; 2020 Sep; 48(9):811-818. PubMed ID: 32601175
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Basic concepts of pharmacokinetic/pharmacodynamic (PK/PD) modelling.
    Meibohm B; Derendorf H
    Int J Clin Pharmacol Ther; 1997 Oct; 35(10):401-13. PubMed ID: 9352388
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Preclinical to Clinical Translation of Antibody-Drug Conjugates Using PK/PD Modeling: a Retrospective Analysis of Inotuzumab Ozogamicin.
    Betts AM; Haddish-Berhane N; Tolsma J; Jasper P; King LE; Sun Y; Chakrapani S; Shor B; Boni J; Johnson TR
    AAPS J; 2016 Sep; 18(5):1101-1116. PubMed ID: 27198897
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Correlation of pharmacokinetics with the antitumor activity of Cetuximab in nude mice bearing the GEO human colon carcinoma xenograft.
    Luo FR; Yang Z; Dong H; Camuso A; McGlinchey K; Fager K; Flefleh C; Kan D; Inigo I; Castaneda S; Rose WC; Kramer RA; Wild R; Lee FY
    Cancer Chemother Pharmacol; 2005 Nov; 56(5):455-64. PubMed ID: 15947929
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Translational PK-PD modeling analysis of MCLA-128, a HER2/HER3 bispecific monoclonal antibody, to predict clinical efficacious exposure and dose.
    de Vries Schultink AHM; Doornbos RP; Bakker ABH; Bol K; Throsby M; Geuijen C; Maussang D; Schellens JHM; Beijnen JH; Huitema ADR
    Invest New Drugs; 2018 Dec; 36(6):1006-1015. PubMed ID: 29728897
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Kinetic-dynamic modeling of lymphocytopenia induced by the combined action of dexamethasone and hydrocortisone in humans, after inhalation and intravenous administration of dexamethasone.
    Braat MC; Oosterhuis B; Koopmans RP; Meewis JM; Van Boxtel CJ
    J Pharmacol Exp Ther; 1992 Aug; 262(2):509-15. PubMed ID: 1501111
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dexamethasone inhibits the effect of paclitaxel on human ovarian carcinoma xenografts in nude mice.
    Hou WJ; Guan JH; Dong Q; Han YH; Zhang R
    Eur Rev Med Pharmacol Sci; 2013 Nov; 17(21):2902-8. PubMed ID: 24254559
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Anti-inflammatory effects of dexamethasone in COVID-19 patients: Translational population PK/PD modeling and simulation.
    ƚwierczek A; Jusko WJ
    Clin Transl Sci; 2023 Sep; 16(9):1667-1679. PubMed ID: 37386717
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pharmacokinetic/Pharmacodynamic Modeling of Schedule-Dependent Interaction between Docetaxel and Cabozantinib in Human Prostate Cancer Xenograft Models.
    Chen W; Chen R; Li J; Fu Y; Yang L; Su H; Yao Y; Li L; Zhou T; Lu W
    J Pharmacol Exp Ther; 2018 Jan; 364(1):13-25. PubMed ID: 29084815
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pharmacokinetics and Pharmacodynamics in Breast Cancer Animal Models.
    Wang W; Nag S; Zhang R
    Methods Mol Biol; 2016; 1406():271-87. PubMed ID: 26820963
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.