236 related articles for article (PubMed ID: 29127155)
1. Tumor suppressor Tsc1 is a new Hsp90 co-chaperone that facilitates folding of kinase and non-kinase clients.
Woodford MR; Sager RA; Marris E; Dunn DM; Blanden AR; Murphy RL; Rensing N; Shapiro O; Panaretou B; Prodromou C; Loh SN; Gutmann DH; Bourboulia D; Bratslavsky G; Wong M; Mollapour M
EMBO J; 2017 Dec; 36(24):3650-3665. PubMed ID: 29127155
[TBL] [Abstract][Full Text] [Related]
2. Emerging Link between Tsc1 and FNIP Co-Chaperones of Hsp90 and Cancer.
Backe SJ; Sager RA; Meluni KA; Woodford MR; Bourboulia D; Mollapour M
Biomolecules; 2022 Jul; 12(7):. PubMed ID: 35883484
[TBL] [Abstract][Full Text] [Related]
3. c-Abl Mediated Tyrosine Phosphorylation of Aha1 Activates Its Co-chaperone Function in Cancer Cells.
Dunn DM; Woodford MR; Truman AW; Jensen SM; Schulman J; Caza T; Remillard TC; Loiselle D; Wolfgeher D; Blagg BS; Franco L; Haystead TA; Daturpalli S; Mayer MP; Trepel JB; Morgan RM; Prodromou C; Kron SJ; Panaretou B; Stetler-Stevenson WG; Landas SK; Neckers L; Bratslavsky G; Bourboulia D; Mollapour M
Cell Rep; 2015 Aug; 12(6):1006-18. PubMed ID: 26235616
[TBL] [Abstract][Full Text] [Related]
4. Evaluation of Hsp90 and mTOR inhibitors as potential drugs for the treatment of TSC1/TSC2 deficient cancer.
Mrozek EM; Bajaj V; Guo Y; Malinowska IA; Zhang J; Kwiatkowski DJ
PLoS One; 2021; 16(4):e0248380. PubMed ID: 33891611
[TBL] [Abstract][Full Text] [Related]
5. Signaling events downstream of mammalian target of rapamycin complex 2 are attenuated in cells and tumors deficient for the tuberous sclerosis complex tumor suppressors.
Huang J; Wu S; Wu CL; Manning BD
Cancer Res; 2009 Aug; 69(15):6107-14. PubMed ID: 19602587
[TBL] [Abstract][Full Text] [Related]
6. Insulin like growth factor-1-induced phosphorylation and altered distribution of tuberous sclerosis complex (TSC)1/TSC2 in C2C12 myotubes.
Miyazaki M; McCarthy JJ; Esser KA
FEBS J; 2010 May; 277(9):2180-91. PubMed ID: 20412061
[TBL] [Abstract][Full Text] [Related]
7. Mutation of the co-chaperone Tsc1 in bladder cancer diminishes Hsp90 acetylation and reduces drug sensitivity and selectivity.
Woodford MR; Hughes M; Sager RA; Backe SJ; Baker-Williams AJ; Bratslavsky MS; Jacob JM; Shapiro O; Wong M; Bratslavsky G; Bourboulia D; Mollapour M
Oncotarget; 2019 Oct; 10(56):5824-5834. PubMed ID: 31645902
[TBL] [Abstract][Full Text] [Related]
8. Aha1 can act as an autonomous chaperone to prevent aggregation of stressed proteins.
Tripathi V; Darnauer S; Hartwig NR; Obermann WM
J Biol Chem; 2014 Dec; 289(52):36220-8. PubMed ID: 25378400
[TBL] [Abstract][Full Text] [Related]
9. The TSC1-TSC2 complex consists of multiple TSC1 and TSC2 subunits.
Hoogeveen-Westerveld M; van Unen L; van den Ouweland A; Halley D; Hoogeveen A; Nellist M
BMC Biochem; 2012 Sep; 13():18. PubMed ID: 23006675
[TBL] [Abstract][Full Text] [Related]
10. Aberrant beta-catenin signaling in tuberous sclerosis.
Mak BC; Kenerson HL; Aicher LD; Barnes EA; Yeung RS
Am J Pathol; 2005 Jul; 167(1):107-16. PubMed ID: 15972957
[TBL] [Abstract][Full Text] [Related]
11. Post-translational Regulation of FNIP1 Creates a Rheostat for the Molecular Chaperone Hsp90.
Sager RA; Woodford MR; Backe SJ; Makedon AM; Baker-Williams AJ; DiGregorio BT; Loiselle DR; Haystead TA; Zachara NE; Prodromou C; Bourboulia D; Schmidt LS; Linehan WM; Bratslavsky G; Mollapour M
Cell Rep; 2019 Jan; 26(5):1344-1356.e5. PubMed ID: 30699359
[TBL] [Abstract][Full Text] [Related]
12. Co-chaperones TIMP2 and AHA1 Competitively Regulate Extracellular HSP90:Client MMP2 Activity and Matrix Proteolysis.
Baker-Williams AJ; Hashmi F; Budzyński MA; Woodford MR; Gleicher S; Himanen SV; Makedon AM; Friedman D; Cortes S; Namek S; Stetler-Stevenson WG; Bratslavsky G; Bah A; Mollapour M; Sistonen L; Bourboulia D
Cell Rep; 2019 Aug; 28(7):1894-1906.e6. PubMed ID: 31412254
[TBL] [Abstract][Full Text] [Related]
13. CHIP: A Co-chaperone for Degradation by the Proteasome and Lysosome.
Chakraborty A; Edkins AL
Subcell Biochem; 2023; 101():351-387. PubMed ID: 36520313
[TBL] [Abstract][Full Text] [Related]
14. The TSC1 and TSC2 tumor suppressors are required for proper ER stress response and protect cells from ER stress-induced apoptosis.
Kang YJ; Lu MK; Guan KL
Cell Death Differ; 2011 Jan; 18(1):133-44. PubMed ID: 20616807
[TBL] [Abstract][Full Text] [Related]
15. Identification of TBC7 having TBC domain as a novel binding protein to TSC1-TSC2 complex.
Nakashima A; Yoshino K; Miyamoto T; Eguchi S; Oshiro N; Kikkawa U; Yonezawa K
Biochem Biophys Res Commun; 2007 Sep; 361(1):218-23. PubMed ID: 17658474
[TBL] [Abstract][Full Text] [Related]
16. The FNIP co-chaperones decelerate the Hsp90 chaperone cycle and enhance drug binding.
Woodford MR; Dunn DM; Blanden AR; Capriotti D; Loiselle D; Prodromou C; Panaretou B; Hughes PF; Smith A; Ackerman W; Haystead TA; Loh SN; Bourboulia D; Schmidt LS; Marston Linehan W; Bratslavsky G; Mollapour M
Nat Commun; 2016 Jun; 7():12037. PubMed ID: 27353360
[TBL] [Abstract][Full Text] [Related]
17. Thr90 phosphorylation of Hsp90α by protein kinase A regulates its chaperone machinery.
Wang X; Lu XA; Song X; Zhuo W; Jia L; Jiang Y; Luo Y
Biochem J; 2012 Jan; 441(1):387-97. PubMed ID: 21919888
[TBL] [Abstract][Full Text] [Related]
18. TBC1D7 is a third subunit of the TSC1-TSC2 complex upstream of mTORC1.
Dibble CC; Elis W; Menon S; Qin W; Klekota J; Asara JM; Finan PM; Kwiatkowski DJ; Murphy LO; Manning BD
Mol Cell; 2012 Aug; 47(4):535-46. PubMed ID: 22795129
[TBL] [Abstract][Full Text] [Related]
19. Biallelic TSC gene inactivation in tuberous sclerosis complex.
Crino PB; Aronica E; Baltuch G; Nathanson KL
Neurology; 2010 May; 74(21):1716-23. PubMed ID: 20498439
[TBL] [Abstract][Full Text] [Related]
20. Hsp90 Chaperones Bluetongue Virus Proteins and Prevents Proteasomal Degradation.
Mohl BP; Roy P
J Virol; 2019 Oct; 93(20):. PubMed ID: 31375577
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
