BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

285 related articles for article (PubMed ID: 29127345)

  • 1. The synthetic neuroactive steroid SGE-516 reduces seizure burden and improves survival in a Dravet syndrome mouse model.
    Hawkins NA; Lewis M; Hammond RS; Doherty JJ; Kearney JA
    Sci Rep; 2017 Nov; 7(1):15327. PubMed ID: 29127345
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Fine Mapping of a Dravet Syndrome Modifier Locus on Mouse Chromosome 5 and Candidate Gene Analysis by RNA-Seq.
    Hawkins NA; Zachwieja NJ; Miller AR; Anderson LL; Kearney JA
    PLoS Genet; 2016 Oct; 12(10):e1006398. PubMed ID: 27768696
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Heterozygous deletion of Gpr55 does not affect a hyperthermia-induced seizure, spontaneous seizures or survival in the Scn1a+/- mouse model of Dravet syndrome.
    Anderson LL; Bahceci DA; Hawkins NA; Everett-Morgan D; Banister SD; Kearney JA; Arnold JC
    PLoS One; 2023; 18(1):e0280842. PubMed ID: 36701411
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Potentiating α
    Nomura T; Hawkins NA; Kearney JA; George AL; Contractor A
    J Physiol; 2019 Aug; 597(16):4293-4307. PubMed ID: 31045243
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Efficacy of stiripentol in hyperthermia-induced seizures in a mouse model of Dravet syndrome.
    Cao D; Ohtani H; Ogiwara I; Ohtani S; Takahashi Y; Yamakawa K; Inoue Y
    Epilepsia; 2012 Jul; 53(7):1140-5. PubMed ID: 22578034
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The endocannabinoid system impacts seizures in a mouse model of Dravet syndrome.
    Anderson LL; Doohan PT; Hawkins NA; Bahceci D; Garai S; Thakur GA; Kearney JA; Arnold JC
    Neuropharmacology; 2022 Mar; 205():108897. PubMed ID: 34822817
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Soticlestat, a novel cholesterol 24-hydroxylase inhibitor, reduces seizures and premature death in Dravet syndrome mice.
    Hawkins NA; Jurado M; Thaxton TT; Duarte SE; Barse L; Tatsukawa T; Yamakawa K; Nishi T; Kondo S; Miyamoto M; Abrahams BS; During MJ; Kearney JA
    Epilepsia; 2021 Nov; 62(11):2845-2857. PubMed ID: 34510432
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Anticonvulsant profile of the neuroactive steroid, SGE-516, in animal models.
    Hammond RS; Althaus AL; Ackley MA; Maciag C; Martinez Botella G; Salituro FG; Robichaud AJ; Doherty JJ
    Epilepsy Res; 2017 Aug; 134():16-25. PubMed ID: 28521115
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Coadministered cannabidiol and clobazam: Preclinical evidence for both pharmacodynamic and pharmacokinetic interactions.
    Anderson LL; Absalom NL; Abelev SV; Low IK; Doohan PT; Martin LJ; Chebib M; McGregor IS; Arnold JC
    Epilepsia; 2019 Nov; 60(11):2224-2234. PubMed ID: 31625159
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Development of an antiseizure drug screening platform for Dravet syndrome at the NINDS contract site for the Epilepsy Therapy Screening Program.
    Pernici CD; Mensah JA; Dahle EJ; Johnson KJ; Handy L; Buxton L; Smith MD; West PJ; Metcalf CS; Wilcox KS
    Epilepsia; 2021 Jul; 62(7):1665-1676. PubMed ID: 34002394
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Selective Na
    Richards KL; Milligan CJ; Richardson RJ; Jancovski N; Grunnet M; Jacobson LH; Undheim EAB; Mobli M; Chow CY; Herzig V; Csoti A; Panyi G; Reid CA; King GF; Petrou S
    Proc Natl Acad Sci U S A; 2018 Aug; 115(34):E8077-E8085. PubMed ID: 30076230
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The synthetic neuroactive steroid SGE-516 reduces status epilepticus and neuronal cell death in a rat model of soman intoxication.
    Althaus AL; McCarren HS; Alqazzaz A; Jackson C; McDonough JH; Smith CD; Hoffman E; Hammond RS; Robichaud AJ; Doherty JJ
    Epilepsy Behav; 2017 Mar; 68():22-30. PubMed ID: 28109985
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The European patient with Dravet syndrome: results from a parent-reported survey on antiepileptic drug use in the European population with Dravet syndrome.
    Aras LM; Isla J; Mingorance-Le Meur A
    Epilepsy Behav; 2015 Mar; 44():104-9. PubMed ID: 25666511
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Proteomic signature of the Dravet syndrome in the genetic Scn1a-A1783V mouse model.
    Miljanovic N; Hauck SM; van Dijk RM; Di Liberto V; Rezaei A; Potschka H
    Neurobiol Dis; 2021 Sep; 157():105423. PubMed ID: 34144125
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Anticonvulsant effect of equilibrative nucleoside transporters 1 inhibitor in a mouse model of Dravet syndrome.
    Ho SY; Chen IC; Tsai CW; Chang KC; Lin CJ; Chern Y; Liou HH
    Hippocampus; 2024 Jan; 34(1):7-13. PubMed ID: 37933097
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Dynamic changes of depolarizing GABA in a computational model of epileptogenic brain: Insight for Dravet syndrome.
    Kurbatova P; Wendling F; Kaminska A; Rosati A; Nabbout R; Guerrini R; Dulac O; Pons G; Cornu C; Nony P; ; Chiron C; Benquet P
    Exp Neurol; 2016 Sep; 283(Pt A):57-72. PubMed ID: 27246997
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Gene expression profiling in a mouse model of Dravet syndrome.
    Hawkins NA; Calhoun JD; Huffman AM; Kearney JA
    Exp Neurol; 2019 Jan; 311():247-256. PubMed ID: 30347190
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Patients with dravet syndrome in the era of stiripentol: A French cohort cross-sectional study.
    De Liso P; Chemaly N; Laschet J; Barnerias C; Hully M; Leunen D; Desguerre I; Chiron C; Dulac O; Nabbout R
    Epilepsy Res; 2016 Sep; 125():42-6. PubMed ID: 27389706
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Donepezil increases resistance to induced seizures in a mouse model of Dravet syndrome.
    Wong JC; Thelin JT; Escayg A
    Ann Clin Transl Neurol; 2019 Aug; 6(8):1566-1571. PubMed ID: 31402621
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Influence of contraindicated medication use on cognitive outcome in Dravet syndrome and age at first afebrile seizure as a clinical predictor in SCN1A-related seizure phenotypes.
    de Lange IM; Gunning B; Sonsma ACM; van Gemert L; van Kempen M; Verbeek NE; Nicolai J; Knoers NVAM; Koeleman BPC; Brilstra EH
    Epilepsia; 2018 Jun; 59(6):1154-1165. PubMed ID: 29750338
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.