BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

247 related articles for article (PubMed ID: 29129529)

  • 1. Profilin Directly Promotes Microtubule Growth through Residues Mutated in Amyotrophic Lateral Sclerosis.
    Henty-Ridilla JL; Juanes MA; Goode BL
    Curr Biol; 2017 Nov; 27(22):3535-3543.e4. PubMed ID: 29129529
    [TBL] [Abstract][Full Text] [Related]  

  • 2. ALS-linked PFN1 variants exhibit loss and gain of functions in the context of formin-induced actin polymerization.
    Schmidt EJ; Funes S; McKeon JE; Morgan BR; Boopathy S; O'Connor LC; Bilsel O; Massi F; Jégou A; Bosco DA
    Proc Natl Acad Sci U S A; 2021 Jun; 118(23):. PubMed ID: 34074767
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A novel phosphorylation site mutation in profilin 1 revealed in a large screen of US, Nordic, and German amyotrophic lateral sclerosis/frontotemporal dementia cohorts.
    Ingre C; Landers JE; Rizik N; Volk AE; Akimoto C; Birve A; Hübers A; Keagle PJ; Piotrowska K; Press R; Andersen PM; Ludolph AC; Weishaupt JH
    Neurobiol Aging; 2013 Jun; 34(6):1708.e1-6. PubMed ID: 23141414
    [TBL] [Abstract][Full Text] [Related]  

  • 4. ALS-causing mutations in profilin-1 alter its conformational dynamics: A computational approach to explain propensity for aggregation.
    Kiaei M; Balasubramaniam M; Govind Kumar V; Shmookler Reis RJ; Moradi M; Varughese KI
    Sci Rep; 2018 Aug; 8(1):13102. PubMed ID: 30166578
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Biochemical characterization of actin assembly mechanisms with ALS-associated profilin variants.
    Liu X; Pimm ML; Haarer B; Brawner AT; Henty-Ridilla JL
    Eur J Cell Biol; 2022 Apr; 101(2):151212. PubMed ID: 35248815
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Profilin 1 with the amyotrophic lateral sclerosis associated mutation T109M displays unaltered actin binding and does not affect the actin cytoskeleton.
    Freischmidt A; Schöpflin M; Feiler MS; Fleck AK; Ludolph AC; Weishaupt JH
    BMC Neurosci; 2015 Nov; 16():77. PubMed ID: 26572741
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Gain-of-function profilin 1 mutations linked to familial amyotrophic lateral sclerosis cause seed-dependent intracellular TDP-43 aggregation.
    Tanaka Y; Nonaka T; Suzuki G; Kametani F; Hasegawa M
    Hum Mol Genet; 2016 Apr; 25(7):1420-33. PubMed ID: 26908597
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutant PFN1 causes ALS phenotypes and progressive motor neuron degeneration in mice by a gain of toxicity.
    Yang C; Danielson EW; Qiao T; Metterville J; Brown RH; Landers JE; Xu Z
    Proc Natl Acad Sci U S A; 2016 Oct; 113(41):E6209-E6218. PubMed ID: 27681617
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Visualizing molecules of functional
    Pimm ML; Liu X; Tuli F; Heritz J; Lojko A; Henty-Ridilla JL
    Elife; 2022 Jun; 11():. PubMed ID: 35666129
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Proximity Proteomics Revealed Aberrant mRNA Splicing Elicited by ALS-Linked Profilin-1 Mutants.
    Wei S; Yang Y; Wang Y
    Anal Chem; 2023 Oct; 95(41):15141-15145. PubMed ID: 37787459
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Amyotrophic lateral sclerosis-associated mutant profilin 1 increases dendritic arborisation and spine formation in primary hippocampal neurons.
    Brettle M; Suchowerska AK; Chua SW; Ittner LM; Fath T
    Neurosci Lett; 2015 Nov; 609():223-8. PubMed ID: 26499959
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A Drosophila model of ALS reveals a partial loss of function of causative human PFN1 mutants.
    Wu CH; Giampetruzzi A; Tran H; Fallini C; Gao FB; Landers JE
    Hum Mol Genet; 2017 Jun; 26(11):2146-2155. PubMed ID: 28379367
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mutations in the profilin 1 gene cause familial amyotrophic lateral sclerosis.
    Wu CH; Fallini C; Ticozzi N; Keagle PJ; Sapp PC; Piotrowska K; Lowe P; Koppers M; McKenna-Yasek D; Baron DM; Kost JE; Gonzalez-Perez P; Fox AD; Adams J; Taroni F; Tiloca C; Leclerc AL; Chafe SC; Mangroo D; Moore MJ; Zitzewitz JA; Xu ZS; van den Berg LH; Glass JD; Siciliano G; Cirulli ET; Goldstein DB; Salachas F; Meininger V; Rossoll W; Ratti A; Gellera C; Bosco DA; Bassell GJ; Silani V; Drory VE; Brown RH; Landers JE
    Nature; 2012 Aug; 488(7412):499-503. PubMed ID: 22801503
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Profilin 1 associates with stress granules and ALS-linked mutations alter stress granule dynamics.
    Figley MD; Bieri G; Kolaitis RM; Taylor JP; Gitler AD
    J Neurosci; 2014 Jun; 34(24):8083-97. PubMed ID: 24920614
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Prolonged depletion of profilin 1 or F-actin causes an adaptive response in microtubules.
    Cisterna BA; Skruber K; Jane ML; Camesi CI; Nguyen ID; Liu TM; Warp PV; Black JB; Butler MT; Bear JE; Mor DE; Read TA; Vitriol EA
    J Cell Biol; 2024 Jul; 223(7):. PubMed ID: 38722279
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Familial Amyotrophic Lateral Sclerosis-linked Mutations in Profilin 1 Exacerbate TDP-43-induced Degeneration in the Retina of Drosophila melanogaster through an Increase in the Cytoplasmic Localization of TDP-43.
    Matsukawa K; Hashimoto T; Matsumoto T; Ihara R; Chihara T; Miura M; Wakabayashi T; Iwatsubo T
    J Biol Chem; 2016 Nov; 291(45):23464-23476. PubMed ID: 27634045
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The actin regulator profilin 1 is functionally associated with the mammalian centrosome.
    Nejedlá M; Klebanovych A; Sulimenko V; Sulimenko T; Dráberová E; Dráber P; Karlsson R
    Life Sci Alliance; 2021 Jan; 4(1):. PubMed ID: 33184056
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Profilin choreographs actin and microtubules in cells and cancer.
    Pimm ML; Hotaling J; Henty-Ridilla JL
    Int Rev Cell Mol Biol; 2020; 355():155-204. PubMed ID: 32859370
    [TBL] [Abstract][Full Text] [Related]  

  • 19. In silico analysis of PFN1 related to amyotrophic lateral sclerosis.
    Pereira GRC; Tellini GHAS; De Mesquita JF
    PLoS One; 2019; 14(6):e0215723. PubMed ID: 31216283
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Profilin as a dual regulator of actin and microtubule dynamics.
    Pinto-Costa R; Sousa MM
    Cytoskeleton (Hoboken); 2020 Mar; 77(3-4):76-83. PubMed ID: 31811707
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.