BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

307 related articles for article (PubMed ID: 29133054)

  • 1. Synthesis, crystal structure and biological evaluation of a new dasatinib copper(II) complex as telomerase inhibitor.
    Qin QP; Meng T; Tan MX; Liu YC; Luo XJ; Zou BQ; Liang H
    Eur J Med Chem; 2018 Jan; 143():1597-1603. PubMed ID: 29133054
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 5-Bromo-oxoisoaporphine platinum(II) complexes exhibit tumor cell cytotoxcicity via inhibition of telomerase activity and disruption of c-myc G-quadruplex DNA and mitochondrial functions.
    Wei ZZ; Qin QP; Meng T; Deng CX; Liang H; Chen ZF
    Eur J Med Chem; 2018 Feb; 145():360-369. PubMed ID: 29335202
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and in vitro antitumor activity evaluation of copper(II) complexes with 5-pyridin-2-yl-[1,3]dioxolo[4,5-g]isoquinoline derivatives.
    Zhang YL; Deng CX; Zhou WF; Zhou LY; Cao QQ; Shen WY; Liang H; Chen ZF
    J Inorg Biochem; 2019 Dec; 201():110820. PubMed ID: 31518871
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and antitumor mechanisms of a copper(II) complex of anthracene-9-imidazoline hydrazone (9-AIH).
    Qin QP; Liu YC; Wang HL; Qin JL; Cheng FJ; Tang SF; Liang H
    Metallomics; 2015 Jul; 7(7):1124-36. PubMed ID: 25904543
    [TBL] [Abstract][Full Text] [Related]  

  • 5. New ferrocene-based 2-thio-imidazol-4-ones and their copper complexes. Synthesis and cytotoxicity.
    Guk DA; Krasnovskaya OO; Dashkova NS; Skvortsov DA; Rubtsova MP; Dyadchenko VP; Yudina ES; Kosarev MA; Soldatov AV; Shapovalov VV; Semkina AS; Vlasova KY; Pergushov VI; Shafikov RR; Moiseeva AA; Andreeva AV; Andreeva AA; Melnikov MY; Zyk NV; Majouga AG; Beloglazkina EK
    Dalton Trans; 2018 Dec; 47(48):17357-17366. PubMed ID: 30480670
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Water-Soluble Ruthenium(II) Complexes with Chiral 4-(2,3-Dihydroxypropyl)-formamide Oxoaporphine (FOA): In Vitro and in Vivo Anticancer Activity by Stabilization of G-Quadruplex DNA, Inhibition of Telomerase Activity, and Induction of Tumor Cell Apoptosis.
    Chen ZF; Qin QP; Qin JL; Zhou J; Li YL; Li N; Liu YC; Liang H
    J Med Chem; 2015 Jun; 58(11):4771-89. PubMed ID: 25988535
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Thiosemicarbazone Cu(II) and Zn(II) complexes as potential anticancer agents: syntheses, crystal structure, DNA cleavage, cytotoxicity and apoptosis induction activity.
    Shao J; Ma ZY; Li A; Liu YH; Xie CZ; Qiang ZY; Xu JY
    J Inorg Biochem; 2014 Jul; 136():13-23. PubMed ID: 24690556
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A mononuclear Cu(II) complex with 5,6-diphenyl-3-(2-pyridyl)-1,2,4-triazine: Synthesis, crystal structure, DNA- and BSA-binding, molecular modeling, and anticancer activity against MCF-7, A-549, and HT-29 cell lines.
    Anjomshoa M; Hadadzadeh H; Torkzadeh-Mahani M; Fatemi SJ; Adeli-Sardou M; Rudbari HA; Nardo VM
    Eur J Med Chem; 2015; 96():66-82. PubMed ID: 25874332
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and in vitro biological evaluation of three 4'-(4-methoxyphenyl)-2,2':6',2″-terpyridine iridium(III) complexes as new telomerase inhibitors.
    Qin QP; Meng T; Tan MX; Liu YC; Luo XJ; Zou BQ; Liang H
    Eur J Med Chem; 2018 Jan; 143():1387-1395. PubMed ID: 29126737
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Molecular basis of structure-activity relationships between salphen metal complexes and human telomeric DNA quadruplexes.
    Campbell NH; Karim NH; Parkinson GN; Gunaratnam M; Petrucci V; Todd AK; Vilar R; Neidle S
    J Med Chem; 2012 Jan; 55(1):209-22. PubMed ID: 22112241
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Copper(ii) l/d-valine-(1,10-phen) complexes target human telomeric G-quadruplex motifs and promote site-specific DNA cleavage and cellular cytotoxicity.
    Arjmand F; Sharma S; Parveen S; Toupet L; Yu Z; Cowan JA
    Dalton Trans; 2020 Jul; 49(28):9888-9899. PubMed ID: 32638779
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A Ce(iii) complex potently inhibits the activity and expression of tyrosine phosphatase SHP-2.
    Lin L; Lu L; Du R; Yuan C; Zhu M; Fu X; Xing S
    Dalton Trans; 2019 Dec; 48(47):17673-17682. PubMed ID: 31763642
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis, crystal structures, molecular docking, and in vitro biological activities of transition metals with 4-(2,3-dichlorophenyl)piperazine-1-carboxylic acid.
    Yang DD; Chen YN; Wu YS; Wang R; Chen ZJ; Qin J; Qian SS; Zhu HL
    Bioorg Med Chem Lett; 2016 Jul; 26(14):3295-3299. PubMed ID: 27241690
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Strong effect of copper(II) coordination on antiproliferative activity of thiosemicarbazone-piperazine and thiosemicarbazone-morpholine hybrids.
    Bacher F; Dömötör O; Chugunova A; Nagy NV; Filipović L; Radulović S; Enyedy ÉA; Arion VB
    Dalton Trans; 2015 May; 44(19):9071-90. PubMed ID: 25896351
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 4-(1H-imidazo[4,5-f]-1,10-phenanthrolin-2-yl)phenol-based G-quadruplex DNA binding agents: telomerase inhibition, cytotoxicity and DNA-binding studies.
    Wei CY; Wang JH; Wen Y; Liu J; Wang LH
    Bioorg Med Chem; 2013 Jun; 21(11):3379-87. PubMed ID: 23611765
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Solvent and Copper Ion-Induced Synthesis of Pyridyl-Pyrazole-3-One Derivatives: Crystal Structure, Cytotoxicity.
    Huang QP; Zhang SN; Zhang SH; Wang K; Xiao Y
    Molecules; 2017 Oct; 22(11):. PubMed ID: 29068409
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Stabilization of G-quadruplex DNA, inhibition of telomerase activity, and tumor cell apoptosis by organoplatinum(II) complexes with oxoisoaporphine.
    Chen ZF; Qin QP; Qin JL; Liu YC; Huang KB; Li YL; Meng T; Zhang GH; Peng Y; Luo XJ; Liang H
    J Med Chem; 2015 Mar; 58(5):2159-79. PubMed ID: 25650792
    [TBL] [Abstract][Full Text] [Related]  

  • 18. New water-soluble copper (II) complexes including 4,7-dimethyl-1,10-phenanthroline and L-tyrosine: synthesis, characterization, DNA interactions and cytotoxicities.
    İnci D; Aydın R; Yılmaz D; Gençkal HM; Vatan Ö; Çinkılıç N; Zorlu Y
    Spectrochim Acta A Mol Biomol Spectrosc; 2015 Feb; 136 Pt B():761-70. PubMed ID: 25448975
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Nitroimidazole and glucosamine conjugated heteroscorpionate ligands and related copper(II) complexes. Syntheses, biological activity and XAS studies.
    Pellei M; Papini G; Trasatti A; Giorgetti M; Tonelli D; Minicucci M; Marzano C; Gandin V; Aquilanti G; Dolmella A; Santini C
    Dalton Trans; 2011 Oct; 40(38):9877-88. PubMed ID: 21709917
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Copper complexes based on chiral Schiff-base ligands: DNA/BSA binding ability, DNA cleavage activity, cytotoxicity and mechanism of apoptosis.
    Zhou XQ; Li Y; Zhang DY; Nie Y; Li ZJ; Gu W; Liu X; Tian JL; Yan SP
    Eur J Med Chem; 2016 May; 114():244-56. PubMed ID: 26994692
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.