BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

550 related articles for article (PubMed ID: 29133525)

  • 1. Optineurin promotes autophagosome formation by recruiting the autophagy-related Atg12-5-16L1 complex to phagophores containing the Wipi2 protein.
    Bansal M; Moharir SC; Sailasree SP; Sirohi K; Sudhakar C; Sarathi DP; Lakshmi BJ; Buono M; Kumar S; Swarup G
    J Biol Chem; 2018 Jan; 293(1):132-147. PubMed ID: 29133525
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Autophagy receptor optineurin promotes autophagosome formation by potentiating LC3-II production and phagophore maturation.
    Bansal M; Moharir SC; Swarup G
    Commun Integr Biol; 2018; 11(2):1-4. PubMed ID: 30083281
    [TBL] [Abstract][Full Text] [Related]  

  • 3. WIPI2 links LC3 conjugation with PI3P, autophagosome formation, and pathogen clearance by recruiting Atg12-5-16L1.
    Dooley HC; Razi M; Polson HE; Girardin SE; Wilson MI; Tooze SA
    Mol Cell; 2014 Jul; 55(2):238-52. PubMed ID: 24954904
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mutations in the ubiquitin-binding domain of OPTN/optineurin interfere with autophagy-mediated degradation of misfolded proteins by a dominant-negative mechanism.
    Shen WC; Li HY; Chen GC; Chern Y; Tu PH
    Autophagy; 2015 Apr; 11(4):685-700. PubMed ID: 25484089
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural basis for membrane recruitment of ATG16L1 by WIPI2 in autophagy.
    Strong LM; Chang C; Riley JF; Boecker CA; Flower TG; Buffalo CZ; Ren X; Stavoe AK; Holzbaur EL; Hurley JH
    Elife; 2021 Sep; 10():. PubMed ID: 34505572
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Interaction between optineurin and Rab1a regulates autophagosome formation in neuroblastoma cells.
    Song GJ; Jeon H; Seo M; Jo M; Suk K
    J Neurosci Res; 2018 Mar; 96(3):407-415. PubMed ID: 28843006
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mammalian Atg18 (WIPI2) localizes to omegasome-anchored phagophores and positively regulates LC3 lipidation.
    Polson HE; de Lartigue J; Rigden DJ; Reedijk M; Urbé S; Clague MJ; Tooze SA
    Autophagy; 2010 May; 6(4):506-22. PubMed ID: 20505359
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hepatitis B Virus Subverts the Autophagy Elongation Complex Atg5-12/16L1 and Does Not Require Atg8/LC3 Lipidation for Viral Maturation.
    Döring T; Zeyen L; Bartusch C; Prange R
    J Virol; 2018 Apr; 92(7):. PubMed ID: 29367244
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The BAX-binding protein MOAP1 associates with LC3 and promotes closure of the phagophore.
    Chang HC; Tao RN; Tan CT; Wu YJ; Bay BH; Yu VC
    Autophagy; 2021 Nov; 17(11):3725-3739. PubMed ID: 33783314
    [TBL] [Abstract][Full Text] [Related]  

  • 10. RAB33B recruits the ATG16L1 complex to the phagophore via a noncanonical RAB binding protein.
    Pantoom S; Konstantinidis G; Voss S; Han H; Hofnagel O; Li Z; Wu YW
    Autophagy; 2021 Sep; 17(9):2290-2304. PubMed ID: 32960676
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A PI3K-WIPI2 positive feedback loop allosterically activates LC3 lipidation in autophagy.
    Fracchiolla D; Chang C; Hurley JH; Martens S
    J Cell Biol; 2020 Jul; 219(7):. PubMed ID: 32437499
    [TBL] [Abstract][Full Text] [Related]  

  • 12. LC3/GABARAPs drive ubiquitin-independent recruitment of Optineurin and NDP52 to amplify mitophagy.
    Padman BS; Nguyen TN; Uoselis L; Skulsuppaisarn M; Nguyen LK; Lazarou M
    Nat Commun; 2019 Jan; 10(1):408. PubMed ID: 30679426
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of a splice variant of optineurin which is defective in autophagy and phosphorylation.
    Moharir SC; Bansal M; Ramachandran G; Ramaswamy R; Rawat S; Raychaudhuri S; Swarup G
    Biochim Biophys Acta Mol Cell Res; 2018 Nov; 1865(11 Pt A):1526-1538. PubMed ID: 30327196
    [TBL] [Abstract][Full Text] [Related]  

  • 14. M98K-OPTN induces transferrin receptor degradation and RAB12-mediated autophagic death in retinal ganglion cells.
    Sirohi K; Chalasani ML; Sudhakar C; Kumari A; Radha V; Swarup G
    Autophagy; 2013 Apr; 9(4):510-27. PubMed ID: 23357852
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A Glaucoma-Associated Variant of Optineurin, M98K, Activates Tbk1 to Enhance Autophagosome Formation and Retinal Cell Death Dependent on Ser177 Phosphorylation of Optineurin.
    Sirohi K; Kumari A; Radha V; Swarup G
    PLoS One; 2015; 10(9):e0138289. PubMed ID: 26376340
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutation.
    Wong YC; Holzbaur EL
    Proc Natl Acad Sci U S A; 2014 Oct; 111(42):E4439-48. PubMed ID: 25294927
    [TBL] [Abstract][Full Text] [Related]  

  • 17. ATG16L1 is equipped with two distinct WIPI2-binding sites to drive autophagy.
    Gong X; Pan L
    Autophagy; 2024 Apr; 20(4):938-940. PubMed ID: 37165562
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The ATG5-binding and coiled coil domains of ATG16L1 maintain autophagy and tissue homeostasis in mice independently of the WD domain required for LC3-associated phagocytosis.
    Rai S; Arasteh M; Jefferson M; Pearson T; Wang Y; Zhang W; Bicsak B; Divekar D; Powell PP; Naumann R; Beraza N; Carding SR; Florey O; Mayer U; Wileman T
    Autophagy; 2019 Apr; 15(4):599-612. PubMed ID: 30403914
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Dynamic and transient interactions of Atg9 with autophagosomes, but not membrane integration, are required for autophagy.
    Orsi A; Razi M; Dooley HC; Robinson D; Weston AE; Collinson LM; Tooze SA
    Mol Biol Cell; 2012 May; 23(10):1860-73. PubMed ID: 22456507
    [TBL] [Abstract][Full Text] [Related]  

  • 20. STING recruits WIPI2 for autophagosome formation.
    Wan W; Liu W
    Autophagy; 2024 Apr; 20(4):928-929. PubMed ID: 37041719
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 28.