BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

79 related articles for article (PubMed ID: 29135287)

  • 1. Molecular modelling studies in explaining the higher GPVI antagonistic activity of the racemic 2-(4-methoxyphenylsulfonyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxamide than its enantiomers.
    Bhunia SS; Saxena AK
    SAR QSAR Environ Res; 2017 Oct; 28(10):783-799. PubMed ID: 29135287
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Novel Glycoprotein VI Antagonists as Antithrombotics: Synthesis, Biological Evaluation, and Molecular Modeling Studies on 2,3-Disubstituted Tetrahydropyrido(3,4-b)indoles.
    Bhunia SS; Misra A; Khan IA; Gaur S; Jain M; Singh S; Saxena A; Hohlfield T; Dikshit M; Saxena AK
    J Med Chem; 2017 Jan; 60(1):322-337. PubMed ID: 27996269
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural basis for platelet antiaggregation by angiotensin II type 1 receptor antagonist losartan (DuP-753) via glycoprotein VI.
    Ono K; Ueda H; Yoshizawa Y; Akazawa D; Tanimura R; Shimada I; Takahashi H
    J Med Chem; 2010 Mar; 53(5):2087-93. PubMed ID: 20158191
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Exploration of the impact of stereochemistry on the identification of the novel translocator protein PET imaging agent [(18)F]GE-180.
    Chau WF; Black AM; Clarke A; Durrant C; Gausemel I; Khan I; Mantzilas D; Oulie I; Rogstad A; Trigg W; Jones PA
    Nucl Med Biol; 2015 Sep; 42(9):711-9. PubMed ID: 26072270
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of Glycoprotein VI Clustering by Collagen as a Mechanism of Inhibiting Collagen-Induced Platelet Responses: The Example of Losartan.
    Jiang P; Loyau S; Tchitchinadze M; Ropers J; Jondeau G; Jandrot-Perrus M
    PLoS One; 2015; 10(6):e0128744. PubMed ID: 26052700
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Insight into stereoselective disposition of enantiomers of a potent antithrombotic agent, S002-333 following administration of the racemic compound to mice.
    Bhateria M; Rachumallu R; Yerrabelli S; Saxena AK; Bhatta RS
    Eur J Pharm Sci; 2017 Apr; 101():107-114. PubMed ID: 28189817
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Soluble glycoprotein VI dimer inhibits platelet adhesion and aggregation to the injured vessel wall in vivo.
    Massberg S; Konrad I; Bültmann A; Schulz C; Münch G; Peluso M; Lorenz M; Schneider S; Besta F; Müller I; Hu B; Langer H; Kremmer E; Rudelius M; Heinzmann U; Ungerer M; Gawaz M
    FASEB J; 2004 Feb; 18(2):397-9. PubMed ID: 14656994
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The Cape Chacma baboon is not suitable for evaluating human targeted anti-GPVI agents.
    Janse van Rensburg WJ; Badenhorst PN; Roodt JP
    Platelets; 2015; 26(6):552-7. PubMed ID: 25165849
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Functionalized tetrahydro-1H-pyrido[4,3-b]indoles: a novel chemotype with Sirtuin 2 inhibitory activity.
    Yang T; Chen X; Jin HX; Sethi G; Go ML
    Eur J Med Chem; 2015 Mar; 92():145-55. PubMed ID: 25549554
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Discovery of novel GPVI receptor antagonists by structure-based repurposing.
    Taylor L; Vasudevan SR; Jones CI; Gibbins JM; Churchill GC; Campbell RD; Coxon CH
    PLoS One; 2014; 9(6):e101209. PubMed ID: 24971515
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Protein binding of indobufen enantiomers: pharmacokinetics of free fraction-studies after single or multiple doses of rac-indobufen.
    Główka FK; Caldwell J
    Chirality; 2002 Oct; 14(9):736-41. PubMed ID: 12237835
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ADPase CD39 Fused to Glycoprotein VI-Fc Boosts Local Antithrombotic Effects at Vascular Lesions.
    Degen H; Borst O; Ziegler M; Mojica Munoz AK; Jamasbi J; Walker B; Göbel S; Fassbender J; Adler K; Brandl R; Münch G; Lorenz R; Siess W; Gawaz M; Ungerer M
    J Am Heart Assoc; 2017 Jul; 6(8):. PubMed ID: 28751543
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Reactivity with DNA bases and mutagenicity toward Salmonella typhimurium of methylchrysene diol epoxide enantiomers.
    Melikian AA; Amin S; Huie K; Hecht SS; Harvey RG
    Cancer Res; 1988 Apr; 48(7):1781-7. PubMed ID: 3258179
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Enantioselective inhibition of reverse transcriptase (RT) of HIV-1 by non-racemic indole-based trifluoropropanoates developed by asymmetric catalysis using recyclable organocatalysts.
    Han X; Ouyang W; Liu B; Wang W; Tien P; Wu S; Zhou HB
    Org Biomol Chem; 2013 Dec; 11(48):8463-75. PubMed ID: 24202207
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure-based discovery of (S)-2-amino-6-(4-fluorobenzyl)-5,6,11,11a-tetrahydro-1H-imidazo[1',5':1,6]pyrido[3,4-b]indole-1,3(2H)-dione as low nanomolar, orally bioavailable autotaxin inhibitor.
    Roy A; Sarkar T; Datta S; Maiti A; Chakrabarti M; Mondal T; Mondal C; Banerjee A; Roy S; Mukherjee S; Muley P; Chakraborty S; Banerjee M; Kundu M; Roy KK
    Chem Biol Drug Des; 2022 Mar; 99(3):496-503. PubMed ID: 34951520
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Computer prediction of paratope on antithrombotic antibody 10B12 and epitope on platelet glycoprotein VI via molecular dynamics simulation.
    Liu W; Liu G; Zhou H; Fang X; Fang Y; Wu J
    Biomed Eng Online; 2016 Dec; 15(Suppl 2):152. PubMed ID: 28155721
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Characterization of the anticonvulsant profile and enantioselective pharmacokinetics of the chiral valproylamide propylisopropyl acetamide in rodents.
    Isoherranen N; Yagen B; Woodhead JH; Spiegelstein O; Blotnik S; Wilcox KS; Finnell RH; Bennett GD; White HS; Bialer M
    Br J Pharmacol; 2003 Feb; 138(4):602-13. PubMed ID: 12598414
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Non-invasive imaging of glycoprotein VI binding to injured arterial lesions.
    Gawaz M; Konrad I; Hauser AI; Sauer S; Li Z; Wester HJ; Bengel FM; Schwaiger M; Schömig A; Massberg S; Haubner R
    Thromb Haemost; 2005 May; 93(5):910-3. PubMed ID: 15886808
    [TBL] [Abstract][Full Text] [Related]  

  • 19. [Advances in the studies of platelet glycoprotein VI (GPVI): review].
    Chu XX; Hou M
    Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2006 Oct; 14(5):1040-4. PubMed ID: 17096916
    [TBL] [Abstract][Full Text] [Related]  

  • 20. EXP3179 inhibits collagen-dependent platelet activation via glycoprotein receptor-VI independent of AT1-receptor antagonism: potential impact on atherothrombosis.
    Grothusen C; Umbreen S; Konrad I; Stellos K; Schulz C; Schmidt B; Kremmer E; Teebken O; Massberg S; Luchtefeld M; Schieffer B; Gawaz M
    Arterioscler Thromb Vasc Biol; 2007 May; 27(5):1184-90. PubMed ID: 17347483
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 4.