BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

311 related articles for article (PubMed ID: 29138063)

  • 1. Polyrotaxane-based systemic delivery of β-cyclodextrins for potentiating therapeutic efficacy in a mouse model of Niemann-Pick type C disease.
    Tamura A; Yui N
    J Control Release; 2018 Jan; 269():148-158. PubMed ID: 29138063
    [TBL] [Abstract][Full Text] [Related]  

  • 2. [Intracellularly Degradable Polyrotaxanes for Therapeutic Applications].
    Tamura A
    Yakugaku Zasshi; 2019; 139(2):143-155. PubMed ID: 30713223
    [TBL] [Abstract][Full Text] [Related]  

  • 3. β-Cyclodextrin-threaded biocleavable polyrotaxanes ameliorate impaired autophagic flux in Niemann-Pick type C disease.
    Tamura A; Yui N
    J Biol Chem; 2015 Apr; 290(15):9442-54. PubMed ID: 25713067
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis of the Anionic Hydroxypropyl-β-cyclodextrin:Poly(decamethylenephosphate) Polyrotaxane and Evaluation of its Cholesterol Efflux Potential in Niemann-Pick C1 Cells.
    Egele K; Samaddar S; Schneider N; Thompson D; Wenz G
    J Mater Chem B; 2019 Jan; 7(4):528-537. PubMed ID: 31372225
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Lysosomal pH-inducible supramolecular dissociation of polyrotaxanes possessing acid-labile
    Tamura A; Nishida K; Yui N
    Sci Technol Adv Mater; 2016; 17(1):361-374. PubMed ID: 27877888
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pluronic based β-cyclodextrin polyrotaxanes for treatment of Niemann-Pick Type C disease.
    Collins CJ; Loren BP; Alam MS; Mondjinou Y; Skulsky JL; Chaplain CR; Haldar K; Thompson DH
    Sci Rep; 2017 Apr; 7():46737. PubMed ID: 28452365
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis of 2-hydroxypropyl-β-cyclodextrin/pluronic-based polyrotaxanes via heterogeneous reaction as potential Niemann-Pick type C therapeutics.
    Mondjinou YA; McCauliff LA; Kulkarni A; Paul L; Hyun SH; Zhang Z; Wu Z; Wirth M; Storch J; Thompson DH
    Biomacromolecules; 2013 Dec; 14(12):4189-97. PubMed ID: 24180231
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Differential mode of cholesterol inclusion with 2-hydroxypropyl-cyclodextrins increases safety margin in treatment of Niemann-Pick disease type C.
    Yamada Y; Ishitsuka Y; Kondo Y; Nakahara S; Nishiyama A; Takeo T; Nakagata N; Motoyama K; Higashi T; Arima H; Kamei S; Shuto T; Kai H; Hayashino Y; Sugita M; Kikuchi T; Hirata F; Miwa T; Takeda H; Orita Y; Seki T; Ohta T; Kurauchi Y; Katsuki H; Matsuo M; Higaki K; Ohno K; Matsumoto S; Era T; Irie T
    Br J Pharmacol; 2021 Jul; 178(13):2727-2746. PubMed ID: 33782944
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Differential Effects of 2-Hydroxypropyl-Cyclodextrins on Lipid Accumulation in
    Hoque S; Kondo Y; Sakata N; Yamada Y; Fukaura M; Higashi T; Motoyama K; Arima H; Higaki K; Hayashi A; Komiya T; Ishitsuka Y; Irie T
    Int J Mol Sci; 2020 Jan; 21(3):. PubMed ID: 32019132
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hydroxypropyl-beta and -gamma cyclodextrins rescue cholesterol accumulation in Niemann-Pick C1 mutant cell via lysosome-associated membrane protein 1.
    Singhal A; Szente L; Hildreth JEK; Song B
    Cell Death Dis; 2018 Oct; 9(10):1019. PubMed ID: 30282967
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Lysosomal-specific cholesterol reduction by biocleavable polyrotaxanes for ameliorating Niemann-Pick type C disease.
    Tamura A; Yui N
    Sci Rep; 2014 Mar; 4():4356. PubMed ID: 24619155
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis, characterization, and evaluation of pluronic-based β-cyclodextrin polyrotaxanes for mobilization of accumulated cholesterol from Niemann-Pick type C fibroblasts.
    Collins CJ; McCauliff LA; Hyun SH; Zhang Z; Paul LN; Kulkarni A; Zick K; Wirth M; Storch J; Thompson DH
    Biochemistry; 2013 May; 52(19):3242-53. PubMed ID: 23560535
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Investigation of 2-Hydroxypropyl-β-Cyclodextrin Treatment in a Neuronal-Like Cell Model of Niemann-Pick Type C Using Quantitative Proteomics.
    Cougnoux A; Pergande MR; Serna-Perez F; Cologna SM
    J Am Soc Mass Spectrom; 2023 Apr; 34(4):668-675. PubMed ID: 36920149
    [TBL] [Abstract][Full Text] [Related]  

  • 14. In Vitro and In Vivo Evaluation of 6-O-α-Maltosyl-β-Cyclodextrin as a Potential Therapeutic Agent Against Niemann-Pick Disease Type C.
    Yasmin N; Ishitsuka Y; Fukaura M; Yamada Y; Nakahara S; Ishii A; Kondo Y; Takeo T; Nakagata N; Motoyama K; Higashi T; Okada Y; Nishikawa J; Ichikawa A; Iohara D; Hirayama F; Higaki K; Ohno K; Matsuo M; Irie T
    Int J Mol Sci; 2019 Mar; 20(5):. PubMed ID: 30845767
    [TBL] [Abstract][Full Text] [Related]  

  • 15. ER stress-mediated autophagic cell death induction through methylated β-cyclodextrins-threaded acid-labile polyrotaxanes.
    Nishida K; Tamura A; Yui N
    J Control Release; 2018 Apr; 275():20-31. PubMed ID: 29428200
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Intracerebroventricular Treatment with 2-Hydroxypropyl-β-Cyclodextrin Decreased Cerebellar and Hepatic Glycoprotein Nonmetastatic Melanoma Protein B (GPNMB) Expression in Niemann-Pick Disease Type C Model Mice.
    Fukaura M; Ishitsuka Y; Shirakawa S; Ushihama N; Yamada Y; Kondo Y; Takeo T; Nakagata N; Motoyama K; Higashi T; Arima H; Kurauchi Y; Seki T; Katsuki H; Higaki K; Matsuo M; Irie T
    Int J Mol Sci; 2021 Jan; 22(1):. PubMed ID: 33466390
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Chronic cyclodextrin treatment of murine Niemann-Pick C disease ameliorates neuronal cholesterol and glycosphingolipid storage and disease progression.
    Davidson CD; Ali NF; Micsenyi MC; Stephney G; Renault S; Dobrenis K; Ory DS; Vanier MT; Walkley SU
    PLoS One; 2009 Sep; 4(9):e6951. PubMed ID: 19750228
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Intracerebroventricular 2-hydroxypropyl-γ-cyclodextrin alleviates hepatic manifestations without distributing to the liver in a murine model of Niemann-Pick disease type C.
    Yamada Y; Ishitsuka Y; Fukaura-Nishizawa M; Kawata T; Ishii A; Shirakawa A; Sakai T; Tanaka M; Kondo Y; Takeo T; Nakagata N; Motoyama K; Higashi T; Arima H; Seki T; Kurauchi Y; Katsuki H; Higaki K; Ikeda R; Matsuo M; Era T; Irie T
    Life Sci; 2024 Aug; 350():122776. PubMed ID: 38852794
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cyclodextrins applied to the treatment of lysosomal storage disorders.
    Ishitsuka Y; Irie T; Matsuo M
    Adv Drug Deliv Rev; 2022 Dec; 191():114617. PubMed ID: 36356931
    [TBL] [Abstract][Full Text] [Related]  

  • 20. In vitro evaluation of 2-hydroxyalkylated β-cyclodextrins as potential therapeutic agents for Niemann-Pick Type C disease.
    Kondo Y; Tokumaru H; Ishitsuka Y; Matsumoto T; Taguchi M; Motoyama K; Higashi T; Arima H; Matsuo M; Higaki K; Ohno K; Irie T
    Mol Genet Metab; 2016 Jul; 118(3):214-219. PubMed ID: 27184436
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.