164 related articles for article (PubMed ID: 29142176)
21. Mode of action and human relevance analysis for nuclear receptor-mediated liver toxicity: A case study with phenobarbital as a model constitutive androstane receptor (CAR) activator.
Elcombe CR; Peffer RC; Wolf DC; Bailey J; Bars R; Bell D; Cattley RC; Ferguson SS; Geter D; Goetz A; Goodman JI; Hester S; Jacobs A; Omiecinski CJ; Schoeny R; Xie W; Lake BG
Crit Rev Toxicol; 2014 Jan; 44(1):64-82. PubMed ID: 24180433
[TBL] [Abstract][Full Text] [Related]
22. Application of humanized mice to toxicology studies: Evaluation of the human relevance of the mode of action for rodent liver tumor formation by activators of the constitutive androstane receptor (CAR).
Yamada T
J Toxicol Pathol; 2021 Oct; 34(4):283-297. PubMed ID: 34629731
[TBL] [Abstract][Full Text] [Related]
23. Comparison of the Hepatic Effects of Phenobarbital in Chimeric Mice Containing Either Rat or Human Hepatocytes With Humanized Constitutive Androstane Receptor and Pregnane X Receptor Mice.
Yamada T; Ohara A; Ozawa N; Maeda K; Kondo M; Okuda Y; Abe J; Cohen SM; Lake BG
Toxicol Sci; 2020 Oct; 177(2):362-376. PubMed ID: 32735318
[TBL] [Abstract][Full Text] [Related]
24. Development of an in vitro high content imaging assay for quantitative assessment of CAR-dependent mouse, rat, and human primary hepatocyte proliferation.
Soldatow V; Peffer RC; Trask OJ; Cowie DE; Andersen ME; LeCluyse E; Deisenroth C
Toxicol In Vitro; 2016 Oct; 36():224-237. PubMed ID: 27530964
[TBL] [Abstract][Full Text] [Related]
25. Mode-of-action analysis for induction of rat liver tumors by pyrethrins: relevance to human cancer risk.
Osimitz TG; Lake BG
Crit Rev Toxicol; 2009; 39(6):501-11. PubMed ID: 19463055
[TBL] [Abstract][Full Text] [Related]
26. Effect of Pyrethrins on cytochrome P450 forms in cultured rat and human hepatocytes.
Price RJ; Giddings AM; Scott MP; Walters DG; Capen CC; Osimitz TG; Lake BG
Toxicology; 2008 Jan; 243(1-2):84-95. PubMed ID: 18022748
[TBL] [Abstract][Full Text] [Related]
27. Involvement of Peroxisome Proliferator-Activated Receptor-Alpha in Liver Tumor Production by Permethrin in the Female Mouse.
Kondo M; Miyata K; Nagahori H; Sumida K; Osimitz TG; Cohen SM; Lake BG; Yamada T
Toxicol Sci; 2019 Apr; 168(2):572-596. PubMed ID: 30629241
[TBL] [Abstract][Full Text] [Related]
28. Analysis of β-catenin gene mutations and gene expression in liver tumours of C57BL/10J mice produced by chronic administration of sodium phenobarbital.
Sidaway JE; Orton TC; Kalaitzi K; Jones HB; Foster A; Lake BG
Toxicology; 2020 Jan; 430():152343. PubMed ID: 31836555
[TBL] [Abstract][Full Text] [Related]
29. Effect of piperonyl butoxide on cell replication and xenobiotic metabolism in the livers of CD-1 mice and F344 rats.
Phillips JC; Price RJ; Cunninghame ME; Osimitz TG; Cockburn A; Gabriel KL; Preiss FJ; Butler WH; Lake BG
Fundam Appl Toxicol; 1997 Jul; 38(1):64-74. PubMed ID: 9268606
[TBL] [Abstract][Full Text] [Related]
30. Squalestatin 1-inducible expression of rat CYP2B: evidence that an endogenous isoprenoid is an activator of the constitutive androstane receptor.
Kocarek TA; Mercer-Haines NA
Mol Pharmacol; 2002 Nov; 62(5):1177-86. PubMed ID: 12391282
[TBL] [Abstract][Full Text] [Related]
31. Role of Phosphatidic Acid Phosphatase Domain Containing 2 in Squalestatin 1-Mediated Activation of the Constitutive Androstane Receptor in Primary Cultured Rat Hepatocytes.
Pant A; Kocarek TA
Drug Metab Dispos; 2016 Mar; 44(3):352-5. PubMed ID: 26700959
[TBL] [Abstract][Full Text] [Related]
32. Negative Regulation of Human Hepatic Constitutive Androstane Receptor by Cholesterol Synthesis Inhibition: Role of Sterol Regulatory Element Binding Proteins.
Cuko L; Duniec-Dmuchowski Z; Rondini EA; Pant A; Fallon JK; Wilson EM; Peraino NJ; Westrick JA; Smith PC; Kocarek TA
Drug Metab Dispos; 2021 Aug; 49(8):706-717. PubMed ID: 34011532
[TBL] [Abstract][Full Text] [Related]
33. A mode of action for induction of thyroid gland tumors by Pyrethrins in the rat.
Finch JM; Osimitz TG; Gabriel KL; Martin T; Henderson WJ; Capen CC; Butler WH; Lake BG
Toxicol Appl Pharmacol; 2006 Aug; 214(3):253-62. PubMed ID: 16626768
[TBL] [Abstract][Full Text] [Related]
34. Enhanced thyroid hormone breakdown in hepatocytes by mutual induction of the constitutive androstane receptor (CAR, NR1I3) and arylhydrocarbon receptor by benzo[a]pyrene and phenobarbital.
Schraplau A; Schewe B; Neuschäfer-Rube F; Ringel S; Neuber C; Kleuser B; Püschel GP
Toxicology; 2015 Feb; 328():21-8. PubMed ID: 25489928
[TBL] [Abstract][Full Text] [Related]
35. Perturbation of rodent hepatocyte growth control by nongenotoxic hepatocarcinogens: mechanisms and lack of relevance for human health (review).
Chevalier S; Roberts RA
Oncol Rep; 1998; 5(6):1319-27. PubMed ID: 9769363
[TBL] [Abstract][Full Text] [Related]
36. Effects of human hepatocyte growth factor on the proliferation of human hepatocytes and hepatocellular carcinoma cell lines.
Efimova EA; Glanemann M; Liu L; Schumacher G; Settmacher U; Jonas S; Langrehr JM; Neuhaus P; Nüssler AK
Eur Surg Res; 2004; 36(5):300-7. PubMed ID: 15359093
[TBL] [Abstract][Full Text] [Related]
37. A novel herbal formulation "LiverCare" differentially regulates primary rat hepatocyte and hepatocarcinoma cell proliferation in vitro.
Vidyashankar S; Varma SR; Azeemudin M; Godavarthi A; Krishna NS; Patki PS
J Med Food; 2011 Sep; 14(9):1023-31. PubMed ID: 21812649
[TBL] [Abstract][Full Text] [Related]
38. Analysis of multiple nuclear receptor binding sites for CAR/RXR in the phenobarbital responsive unit of CYP2B2.
Zhang Q; Bae Y; Kemper JK; Kemper B
Arch Biochem Biophys; 2006 Jul; 451(2):119-27. PubMed ID: 16725103
[TBL] [Abstract][Full Text] [Related]
39. Human relevance framework for rodent liver tumors induced by the insecticide sulfoxaflor.
LeBaron MJ; Gollapudi BB; Terry C; Billington R; Rasoulpour RJ
Crit Rev Toxicol; 2014 May; 44 Suppl 2():15-24. PubMed ID: 24832551
[TBL] [Abstract][Full Text] [Related]
40. Mode of action of butoxyethanol-induced mouse liver hemangiosarcomas and hepatocellular carcinomas.
Klaunig JE; Kamendulis LM
Toxicol Lett; 2005 Mar; 156(1):107-15. PubMed ID: 15705491
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]