These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

353 related articles for article (PubMed ID: 29146439)

  • 1. Risk stratification after paracetamol overdose using mechanistic biomarkers: results from two prospective cohort studies.
    Dear JW; Clarke JI; Francis B; Allen L; Wraight J; Shen J; Dargan PI; Wood D; Cooper J; Thomas SHL; Jorgensen AL; Pirmohamed M; Park BK; Antoine DJ
    Lancet Gastroenterol Hepatol; 2018 Feb; 3(2):104-113. PubMed ID: 29146439
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mechanistic biomarkers provide early and sensitive detection of acetaminophen-induced acute liver injury at first presentation to hospital.
    Antoine DJ; Dear JW; Lewis PS; Platt V; Coyle J; Masson M; Thanacoody RH; Gray AJ; Webb DJ; Moggs JG; Bateman DN; Goldring CE; Park BK
    Hepatology; 2013 Aug; 58(2):777-87. PubMed ID: 23390034
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cytokeratin-18 is a sensitive biomarker of alanine transaminase increase in a placebo-controlled, randomized, crossover trial of therapeutic paracetamol dosing (PATH-BP biomarker substudy).
    Scullion KM; MacIntyre IM; Sloan-Dennison S; Clark B; Fineran P; Mair J; Creasey D; Rathmell C; Faulds K; Graham D; Webb DJ; Dear JW
    Toxicol Sci; 2024 May; 199(2):203-209. PubMed ID: 38521541
    [TBL] [Abstract][Full Text] [Related]  

  • 4. RETRACTED: Molecular forms of HMGB1 and keratin-18 as mechanistic biomarkers for mode of cell death and prognosis during clinical acetaminophen hepatotoxicity.
    Antoine DJ; Jenkins RE; Dear JW; Williams DP; McGill MR; Sharpe MR; Craig DG; Simpson KJ; Jaeschke H; Park BK
    J Hepatol; 2012 May; 56(5):1070-1079. PubMed ID: 22266604
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Target biomarker profile for the clinical management of paracetamol overdose.
    Vliegenthart AD; Antoine DJ; Dear JW
    Br J Clin Pharmacol; 2015 Sep; 80(3):351-62. PubMed ID: 26076366
    [TBL] [Abstract][Full Text] [Related]  

  • 6. External validation of the paracetamol-aminotransferase multiplication product to predict hepatotoxicity from paracetamol overdose.
    Wong A; Sivilotti ML; Dargan PI; Wood DM; Greene SL
    Clin Toxicol (Phila); 2015; 53(8):807-14. PubMed ID: 26175095
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Risk prediction of hepatotoxicity in paracetamol poisoning.
    Wong A; Graudins A
    Clin Toxicol (Phila); 2017 Sep; 55(8):879-892. PubMed ID: 28447858
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Outcomes from massive paracetamol overdose: a retrospective observational study.
    Marks DJB; Dargan PI; Archer JRH; Davies CL; Dines AM; Wood DM; Greene SL
    Br J Clin Pharmacol; 2017 Jun; 83(6):1263-1272. PubMed ID: 28002875
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Accuracy of the paracetamol-aminotransferase multiplication product to predict hepatotoxicity in modified-release paracetamol overdose.
    Wong A; Sivilotti MLA; Graudins A
    Clin Toxicol (Phila); 2017 Jun; 55(5):346-351. PubMed ID: 28421844
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Plasma paracetamol concentration at hospital presentation has a dose-dependent relationship with liver injury despite prompt treatment with intravenous acetylcysteine.
    Cairney DG; Beckwith HK; Al-Hourani K; Eddleston M; Bateman DN; Dear JW
    Clin Toxicol (Phila); 2016 Jun; 54(5):405-10. PubMed ID: 27108714
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Fifty years of paracetamol (acetaminophen) poisoning: the development of risk assessment and treatment 1973-2023 with particular focus on contributions published from Edinburgh and Denver.
    Bateman DN; Dart RC; Dear JW; Prescott LF; Rumack BH
    Clin Toxicol (Phila); 2023 Dec; 61(12):1020-1031. PubMed ID: 38197864
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A descriptive analysis of aspartate and alanine aminotransferase rise and fall following acetaminophen overdose.
    Curtis RM; Sivilotti ML
    Clin Toxicol (Phila); 2015 Nov; 53(9):849-55. PubMed ID: 26294195
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Principal results of a randomised open label exploratory, safety and tolerability study with calmangafodipir in patients treated with a 12 h regimen of N-acetylcysteine for paracetamol overdose (POP trial).
    Morrison EE; Oatey K; Gallagher B; Grahamslaw J; O'Brien R; Black P; Oosthuyzen W; Lee RJ; Weir CJ; Henriksen D; Dear JW;
    EBioMedicine; 2019 Aug; 46():423-430. PubMed ID: 31311721
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The predictive value of hospital admission serum alanine transaminase activity in patients treated for paracetamol overdose.
    Al-Hourani K; Mansi R; Pettie J; Dow M; Bateman DN; Dear JW
    QJM; 2013 Jun; 106(6):541-6. PubMed ID: 23550167
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Circulating apoptotic and necrotic cell death markers in patients with acute liver injury.
    Craig DG; Lee P; Pryde EA; Masterton GS; Hayes PC; Simpson KJ
    Liver Int; 2011 Sep; 31(8):1127-36. PubMed ID: 21745283
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Nomogram line crossing after acetaminophen combination product overdose.
    Kirschner RI; Rozier CM; Smith LM; Jacobitz KL
    Clin Toxicol (Phila); 2016; 54(1):40-6. PubMed ID: 26567585
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Circulating acetaminophen metabolites are toxicokinetic biomarkers of acute liver injury.
    Vliegenthart A; Kimmitt RA; Seymour JH; Homer NZ; Clarke JI; Eddleston M; Gray A; Wood DM; Dargan PI; Cooper JG; Antoine DJ; Webb DJ; Lewis SC; Bateman DN; Dear JW
    Clin Pharmacol Ther; 2017 Apr; 101(4):531-540. PubMed ID: 27770431
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Changing the Management of Paracetamol Poisoning.
    Bateman DN
    Clin Ther; 2015 Sep; 37(9):2135-41. PubMed ID: 26233473
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Paracetamol metabolite concentrations following low risk overdose treated with an abbreviated 12-h versus 20-h acetylcysteine infusion.
    Wong A; Homer N; Dear JW; Choy KW; Doery J; Graudins A
    Clin Toxicol (Phila); 2019 May; 57(5):312-317. PubMed ID: 30453788
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Modified release paracetamol overdose: a prospective observational study (ATOM-3).
    Chiew AL; Isbister GK; Page CB; Kirby KA; Chan BSH; Buckley NA
    Clin Toxicol (Phila); 2018 Sep; 56(9):810-819. PubMed ID: 29451045
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.