BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

173 related articles for article (PubMed ID: 29149195)

  • 1. Age of heart disease presentation and dysmorphic nuclei in patients with LMNA mutations.
    Core JQ; Mehrabi M; Robinson ZR; Ochs AR; McCarthy LA; Zaragoza MV; Grosberg A
    PLoS One; 2017; 12(11):e0188256. PubMed ID: 29149195
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dermal fibroblasts in Hutchinson-Gilford progeria syndrome with the lamin A G608G mutation have dysmorphic nuclei and are hypersensitive to heat stress.
    Paradisi M; McClintock D; Boguslavsky RL; Pedicelli C; Worman HJ; Djabali K
    BMC Cell Biol; 2005 Jun; 6():27. PubMed ID: 15982412
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mechanics in human fibroblasts and progeria: Lamin A mutation E145K results in stiffening of nuclei.
    Apte K; Stick R; Radmacher M
    J Mol Recognit; 2017 Feb; 30(2):. PubMed ID: 27677907
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hutchinson-Gilford progeria mutant lamin A primarily targets human vascular cells as detected by an anti-Lamin A G608G antibody.
    McClintock D; Gordon LB; Djabali K
    Proc Natl Acad Sci U S A; 2006 Feb; 103(7):2154-9. PubMed ID: 16461887
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Soft substrates normalize nuclear morphology and prevent nuclear rupture in fibroblasts from a laminopathy patient with compound heterozygous LMNA mutations.
    Tamiello C; Kamps MA; van den Wijngaard A; Verstraeten VL; Baaijens FP; Broers JL; Bouten CC
    Nucleus; 2013; 4(1):61-73. PubMed ID: 23324461
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Phosphorylated Lamin A/C in the Nuclear Interior Binds Active Enhancers Associated with Abnormal Transcription in Progeria.
    Ikegami K; Secchia S; Almakki O; Lieb JD; Moskowitz IP
    Dev Cell; 2020 Mar; 52(6):699-713.e11. PubMed ID: 32208162
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A conserved splicing mechanism of the LMNA gene controls premature aging.
    Lopez-Mejia IC; Vautrot V; De Toledo M; Behm-Ansmant I; Bourgeois CF; Navarro CL; Osorio FG; Freije JM; Stévenin J; De Sandre-Giovannoli A; Lopez-Otin C; Lévy N; Branlant C; Tazi J
    Hum Mol Genet; 2011 Dec; 20(23):4540-55. PubMed ID: 21875900
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Incomplete processing of mutant lamin A in Hutchinson-Gilford progeria leads to nuclear abnormalities, which are reversed by farnesyltransferase inhibition.
    Glynn MW; Glover TW
    Hum Mol Genet; 2005 Oct; 14(20):2959-69. PubMed ID: 16126733
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Nesprin-2 giant safeguards nuclear envelope architecture in LMNA S143F progeria cells.
    Kandert S; Lüke Y; Kleinhenz T; Neumann S; Lu W; Jaeger VM; Munck M; Wehnert M; Müller CR; Zhou Z; Noegel AA; Dabauvalle MC; Karakesisoglou I
    Hum Mol Genet; 2007 Dec; 16(23):2944-59. PubMed ID: 17881656
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A Novel Lamin A Mutant Responsible for Congenital Muscular Dystrophy Causes Distinct Abnormalities of the Cell Nucleus.
    Barateau A; Vadrot N; Vicart P; Ferreiro A; Mayer M; Héron D; Vigouroux C; Buendia B
    PLoS One; 2017; 12(1):e0169189. PubMed ID: 28125586
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of novel RNA isoforms of LMNA.
    DeBoy E; Puttaraju M; Jailwala P; Kasoji M; Cam M; Misteli T
    Nucleus; 2017 Sep; 8(5):573-582. PubMed ID: 28857661
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Amphibian oocyte nuclei expressing lamin A with the progeria mutation E145K exhibit an increased elastic modulus.
    Kaufmann A; Heinemann F; Radmacher M; Stick R
    Nucleus; 2011; 2(4):310-9. PubMed ID: 21941106
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Hutchinson-Gilford progeria syndrome through the lens of transcription.
    Prokocimer M; Barkan R; Gruenbaum Y
    Aging Cell; 2013 Aug; 12(4):533-43. PubMed ID: 23496208
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Hutchinson-Gilford progeria syndrome.
    Pollex RL; Hegele RA
    Clin Genet; 2004 Nov; 66(5):375-81. PubMed ID: 15479179
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Compound heterozygosity for mutations in LMNA causes a progeria syndrome without prelamin A accumulation.
    Verstraeten VL; Broers JL; van Steensel MA; Zinn-Justin S; Ramaekers FC; Steijlen PM; Kamps M; Kuijpers HJ; Merckx D; Smeets HJ; Hennekam RC; Marcelis CL; van den Wijngaard A
    Hum Mol Genet; 2006 Aug; 15(16):2509-22. PubMed ID: 16825282
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Accumulation of mutant lamin A causes progressive changes in nuclear architecture in Hutchinson-Gilford progeria syndrome.
    Goldman RD; Shumaker DK; Erdos MR; Eriksson M; Goldman AE; Gordon LB; Gruenbaum Y; Khuon S; Mendez M; Varga R; Collins FS
    Proc Natl Acad Sci U S A; 2004 Jun; 101(24):8963-8. PubMed ID: 15184648
    [TBL] [Abstract][Full Text] [Related]  

  • 17. LMNA mutation in a 45 year old Japanese subject with Hutchinson-Gilford progeria syndrome.
    Fukuchi K; Katsuya T; Sugimoto K; Kuremura M; Kim HD; Li L; Ogihara T
    J Med Genet; 2004 May; 41(5):e67. PubMed ID: 15121795
    [No Abstract]   [Full Text] [Related]  

  • 18. Accurate Detection of Dysmorphic Nuclei Using Dynamic Programming and Supervised Classification.
    Verschuuren M; De Vylder J; Catrysse H; Robijns J; Philips W; De Vos WH
    PLoS One; 2017; 12(1):e0170688. PubMed ID: 28125723
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Rescue of heterochromatin organization in Hutchinson-Gilford progeria by drug treatment.
    Columbaro M; Capanni C; Mattioli E; Novelli G; Parnaik VK; Squarzoni S; Maraldi NM; Lattanzi G
    Cell Mol Life Sci; 2005 Nov; 62(22):2669-78. PubMed ID: 16261260
    [TBL] [Abstract][Full Text] [Related]  

  • 20. [Hutchinson-Gilford progeria in the light of contemporary genetics].
    Madej-Pilarczyk A
    Med Wieku Rozwoj; 2006; 10(1 Pt 2):355-62. PubMed ID: 17028399
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.