324 related articles for article (PubMed ID: 29149604)
1. NRF1 Is an ER Membrane Sensor that Is Central to Cholesterol Homeostasis.
Widenmaier SB; Snyder NA; Nguyen TB; Arduini A; Lee GY; Arruda AP; Saksi J; Bartelt A; Hotamisligil GS
Cell; 2017 Nov; 171(5):1094-1109.e15. PubMed ID: 29149604
[TBL] [Abstract][Full Text] [Related]
2. Activation of the membrane-bound Nrf1 transcription factor by USP19, a ubiquitin-specific protease C-terminally anchored in the endoplasmic reticulum.
Hu S; Xiang Y; Qiu L; Wang M; Zhang Y
Biochim Biophys Acta Mol Cell Res; 2022 Sep; 1869(9):119299. PubMed ID: 35613680
[TBL] [Abstract][Full Text] [Related]
3. Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity.
Bartelt A; Widenmaier SB; Schlein C; Johann K; Goncalves RLS; Eguchi K; Fischer AW; Parlakgül G; Snyder NA; Nguyen TB; Bruns OT; Franke D; Bawendi MG; Lynes MD; Leiria LO; Tseng YH; Inouye KE; Arruda AP; Hotamisligil GS
Nat Med; 2018 Mar; 24(3):292-303. PubMed ID: 29400713
[TBL] [Abstract][Full Text] [Related]
4. A Homeostatic Shift Facilitates Endoplasmic Reticulum Proteostasis through Transcriptional Integration of Proteostatic Stress Response Pathways.
Baird L; Tsujita T; Kobayashi EH; Funayama R; Nagashima T; Nakayama K; Yamamoto M
Mol Cell Biol; 2017 Feb; 37(4):. PubMed ID: 27920251
[TBL] [Abstract][Full Text] [Related]
5. Identification of topological determinants in the N-terminal domain of transcription factor Nrf1 that control its orientation in the endoplasmic reticulum membrane.
Zhang Y; Hayes JD
Biochem J; 2010 Sep; 430(3):497-510. PubMed ID: 20629635
[TBL] [Abstract][Full Text] [Related]
6. Negative regulation of the Nrf1 transcription factor by its N-terminal domain is independent of Keap1: Nrf1, but not Nrf2, is targeted to the endoplasmic reticulum.
Zhang Y; Crouch DH; Yamamoto M; Hayes JD
Biochem J; 2006 Nov; 399(3):373-85. PubMed ID: 16872277
[TBL] [Abstract][Full Text] [Related]
7. Synergism and Antagonism of Two Distinct, but Confused, Nrf1 Factors in Integral Regulation of the Nuclear-to-Mitochondrial Respiratory and Antioxidant Transcription Networks.
Zhang S; Deng Y; Xiang Y; Hu S; Qiu L; Zhang Y
Oxid Med Cell Longev; 2020; 2020():5097109. PubMed ID: 33376579
[TBL] [Abstract][Full Text] [Related]
8. Induction of Herpud1 expression by ER stress is regulated by Nrf1.
Ho DV; Chan JY
FEBS Lett; 2015 Feb; 589(5):615-20. PubMed ID: 25637874
[TBL] [Abstract][Full Text] [Related]
9. ER-Resident Transcription Factor Nrf1 Regulates Proteasome Expression and Beyond.
Hamazaki J; Murata S
Int J Mol Sci; 2020 May; 21(10):. PubMed ID: 32456207
[TBL] [Abstract][Full Text] [Related]
10. Nrf1 is targeted to the endoplasmic reticulum membrane by an N-terminal transmembrane domain. Inhibition of nuclear translocation and transacting function.
Wang W; Chan JY
J Biol Chem; 2006 Jul; 281(28):19676-87. PubMed ID: 16687406
[TBL] [Abstract][Full Text] [Related]
11. Nuclear factor-erythroid 2-related factor 1 regulates expression of proteasome genes in hepatocytes and protects against endoplasmic reticulum stress and steatosis in mice.
Lee CS; Ho DV; Chan JY
FEBS J; 2013 Aug; 280(15):3609-20. PubMed ID: 23702335
[TBL] [Abstract][Full Text] [Related]
12. Regulation and Functions of the ER-Associated Nrf1 Transcription Factor.
Ruvkun G; Lehrbach N
Cold Spring Harb Perspect Biol; 2023 Jan; 15(1):. PubMed ID: 35940907
[TBL] [Abstract][Full Text] [Related]
13. The C-terminal domain of Nrf1 negatively regulates the full-length CNC-bZIP factor and its shorter isoform LCR-F1/Nrf1β; both are also inhibited by the small dominant-negative Nrf1γ/δ isoforms that down-regulate ARE-battery gene expression.
Zhang Y; Qiu L; Li S; Xiang Y; Chen J; Ren Y
PLoS One; 2014; 9(10):e109159. PubMed ID: 25290918
[TBL] [Abstract][Full Text] [Related]
14. Changing gears in Nrf1 research, from mechanisms of regulation to its role in disease and prevention.
Bugno M; Daniel M; Chepelev NL; Willmore WG
Biochim Biophys Acta; 2015 Oct; 1849(10):1260-76. PubMed ID: 26254094
[TBL] [Abstract][Full Text] [Related]
15. Complementary gene regulation by NRF1 and NRF2 protects against hepatic cholesterol overload.
Akl MG; Li L; Baccetto R; Phanse S; Zhang Q; Trites MJ; McDonald S; Aoki H; Babu M; Widenmaier SB
Cell Rep; 2023 Apr; 42(4):112399. PubMed ID: 37060561
[TBL] [Abstract][Full Text] [Related]
16. USP15 stabilizes the transcription factor Nrf1 in the nucleus, promoting the proteasome gene expression.
Fukagai K; Waku T; Chowdhury AMMA; Kubo K; Matsumoto M; Kato H; Natsume T; Tsuruta F; Chiba T; Taniguchi H; Kobayashi A
Biochem Biophys Res Commun; 2016 Sep; 478(1):363-370. PubMed ID: 27416755
[TBL] [Abstract][Full Text] [Related]
17. Nrf1 can be processed and activated in a proteasome-independent manner.
Vangala JR; Sotzny F; Krüger E; Deshaies RJ; Radhakrishnan SK
Curr Biol; 2016 Sep; 26(18):R834-R835. PubMed ID: 27676297
[TBL] [Abstract][Full Text] [Related]
18. Cholesterol metabolism and the pathogenesis of non-alcoholic steatohepatitis.
Musso G; Gambino R; Cassader M
Prog Lipid Res; 2013 Jan; 52(1):175-91. PubMed ID: 23206728
[TBL] [Abstract][Full Text] [Related]
19. The Nrf1 CNC/bZIP protein is a nuclear envelope-bound transcription factor that is activated by t-butyl hydroquinone but not by endoplasmic reticulum stressors.
Zhang Y; Lucocq JM; Hayes JD
Biochem J; 2009 Mar; 418(2):293-310. PubMed ID: 18990090
[TBL] [Abstract][Full Text] [Related]
20. Euglycemia is affected by stress defense factor hepatocyte NRF1, but not NRF2.
Akl MG; Baccetto R; Stebbings BM; Li L; Widenmaier SB
Biochem Biophys Res Commun; 2023 Aug; 668():96-103. PubMed ID: 37245295
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]