542 related articles for article (PubMed ID: 29155882)
1. Pharmacological inhibition of RORγt suppresses the Th17 pathway and alleviates arthritis in vivo.
Guendisch U; Weiss J; Ecoeur F; Riker JC; Kaupmann K; Kallen J; Hintermann S; Orain D; Dawson J; Billich A; Guntermann C
PLoS One; 2017; 12(11):e0188391. PubMed ID: 29155882
[TBL] [Abstract][Full Text] [Related]
2. Antagonizing Retinoic Acid-Related-Orphan Receptor Gamma Activity Blocks the T Helper 17/Interleukin-17 Pathway Leading to Attenuated Pro-inflammatory Human Keratinocyte and Skin Responses.
Ecoeur F; Weiss J; Kaupmann K; Hintermann S; Orain D; Guntermann C
Front Immunol; 2019; 10():577. PubMed ID: 30972071
[TBL] [Abstract][Full Text] [Related]
3. Pharmacologic inhibition of RORγt regulates Th17 signature gene expression and suppresses cutaneous inflammation in vivo.
Skepner J; Ramesh R; Trocha M; Schmidt D; Baloglu E; Lobera M; Carlson T; Hill J; Orband-Miller LA; Barnes A; Boudjelal M; Sundrud M; Ghosh S; Yang J
J Immunol; 2014 Mar; 192(6):2564-75. PubMed ID: 24516202
[TBL] [Abstract][Full Text] [Related]
4. The immunomodulatory effects of TNF-α inhibitors on human Th17 cells via RORγt histone acetylation.
Lin YC; Lin YC; Wu CC; Huang MY; Tsai WC; Hung CH; Kuo PL
Oncotarget; 2017 Jan; 8(5):7559-7571. PubMed ID: 27926504
[TBL] [Abstract][Full Text] [Related]
5. Identification of Tetraazacyclic Compounds as Novel Potent Inhibitors Antagonizing RORγt Activity and Suppressing Th17 Cell Differentiation.
Ding Q; Zhao M; Yu B; Bai C; Huang Z
PLoS One; 2015; 10(9):e0137711. PubMed ID: 26368822
[TBL] [Abstract][Full Text] [Related]
6. Pharmacologic modulation of RORγt translates to efficacy in preclinical and translational models of psoriasis and inflammatory arthritis.
Xue X; Soroosh P; De Leon-Tabaldo A; Luna-Roman R; Sablad M; Rozenkrants N; Yu J; Castro G; Banie H; Fung-Leung WP; Santamaria-Babi L; Schlueter T; Albers M; Leonard K; Budelsky AL; Fourie AM
Sci Rep; 2016 Dec; 6():37977. PubMed ID: 27905482
[TBL] [Abstract][Full Text] [Related]
7. RORγt-specific transcriptional interactomic inhibition suppresses autoimmunity associated with TH17 cells.
Park TY; Park SD; Cho JY; Moon JS; Kim NY; Park K; Seong RH; Lee SW; Morio T; Bothwell AL; Lee SK
Proc Natl Acad Sci U S A; 2014 Dec; 111(52):18673-8. PubMed ID: 25527718
[TBL] [Abstract][Full Text] [Related]
8. AT-rich-interactive domain-containing protein 5A functions as a negative regulator of retinoic acid receptor-related orphan nuclear receptor γt-induced Th17 cell differentiation.
Saito Y; Kagami S; Sanayama Y; Ikeda K; Suto A; Kashiwakuma D; Furuta S; Iwamoto I; Nonaka K; Ohara O; Nakajima H
Arthritis Rheumatol; 2014 May; 66(5):1185-94. PubMed ID: 24782182
[TBL] [Abstract][Full Text] [Related]
9. In vivo regulation of gene expression and T helper type 17 differentiation by RORγt inverse agonists.
Skepner J; Trocha M; Ramesh R; Qu XA; Schmidt D; Baloglu E; Lobera M; Davis S; Nolan MA; Carlson TJ; Hill J; Ghosh S; Sundrud MS; Yang J
Immunology; 2015 Jul; 145(3):347-56. PubMed ID: 25604624
[TBL] [Abstract][Full Text] [Related]
10. Inhibiting RORγt/Th17 axis for autoimmune disorders.
Isono F; Fujita-Sato S; Ito S
Drug Discov Today; 2014 Aug; 19(8):1205-11. PubMed ID: 24792721
[TBL] [Abstract][Full Text] [Related]
11. Pharmacological inhibitory profile of TAK-828F, a potent and selective orally available RORγt inverse agonist.
Shibata A; Uga K; Sato T; Sagara M; Igaki K; Nakamura Y; Ochida A; Kono M; Shirai J; Yamamoto S; Yamasaki M; Tsuchimori N
Biochem Pharmacol; 2018 Apr; 150():35-45. PubMed ID: 29369782
[TBL] [Abstract][Full Text] [Related]
12. Inhibition of RORγt activity and Th17 differentiation by a set of novel compounds.
Ding Q; Zhao M; Bai C; Yu B; Huang Z
BMC Immunol; 2015 May; 16():32. PubMed ID: 26021566
[TBL] [Abstract][Full Text] [Related]
13. Small molecule inhibitors of RORγt: targeting Th17 cells and other applications.
Huh JR; Littman DR
Eur J Immunol; 2012 Sep; 42(9):2232-7. PubMed ID: 22949321
[TBL] [Abstract][Full Text] [Related]
14. Preclinical and clinical characterization of the RORγt inhibitor JNJ-61803534.
Xue X; De Leon-Tabaldo A; Luna-Roman R; Castro G; Albers M; Schoetens F; DePrimo S; Devineni D; Wilde T; Goldberg S; Kinzel O; Hoffmann T; Fourie AM; Thurmond RL
Sci Rep; 2021 May; 11(1):11066. PubMed ID: 34040108
[TBL] [Abstract][Full Text] [Related]
15. Interleukin-23 is critical for full-blown expression of a non-autoimmune destructive arthritis and regulates interleukin-17A and RORgammat in gammadelta T cells.
Cornelissen F; Mus AM; Asmawidjaja PS; van Hamburg JP; Tocker J; Lubberts E
Arthritis Res Ther; 2009; 11(6):R194. PubMed ID: 20017902
[TBL] [Abstract][Full Text] [Related]
16. Nuclear orphan receptor NR2F6 directly antagonizes NFAT and RORγt binding to the Il17a promoter.
Hermann-Kleiter N; Meisel M; Fresser F; Thuille N; Müller M; Roth L; Katopodis A; Baier G
J Autoimmun; 2012 Dec; 39(4):428-40. PubMed ID: 22921335
[TBL] [Abstract][Full Text] [Related]
17. Structural basis of digoxin that antagonizes RORgamma t receptor activity and suppresses Th17 cell differentiation and interleukin (IL)-17 production.
Fujita-Sato S; Ito S; Isobe T; Ohyama T; Wakabayashi K; Morishita K; Ando O; Isono F
J Biol Chem; 2011 Sep; 286(36):31409-17. PubMed ID: 21733845
[TBL] [Abstract][Full Text] [Related]
18. Metformin downregulates Th17 cells differentiation and attenuates murine autoimmune arthritis.
Kang KY; Kim YK; Yi H; Kim J; Jung HR; Kim IJ; Cho JH; Park SH; Kim HY; Ju JH
Int Immunopharmacol; 2013 May; 16(1):85-92. PubMed ID: 23557965
[TBL] [Abstract][Full Text] [Related]
19. Concomitant suppression of T
Na H; Lim H; Choi G; Kim BK; Kim SH; Chang YS; Nurieva R; Dong C; Chang SH; Chung Y
J Allergy Clin Immunol; 2018 Jun; 141(6):2061-2073.e5. PubMed ID: 28943467
[TBL] [Abstract][Full Text] [Related]
20. Novel benzenediamine derivative FC99 ameliorates zymosan-induced arthritis by inhibiting RORγt expression and Th17 cell differentiation.
Ji J; Dou H; Li X; Song Y; Li X; Li E; Tan R; Hou Y
Acta Biochim Biophys Sin (Shanghai); 2014 Oct; 46(10):829-36. PubMed ID: 25187413
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
