These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

407 related articles for article (PubMed ID: 29157079)

  • 21. Glycogen Synthase Kinase-3 Inhibition Sensitizes Pancreatic Cancer Cells to Chemotherapy by Abrogating the TopBP1/ATR-Mediated DNA Damage Response.
    Ding L; Madamsetty VS; Kiers S; Alekhina O; Ugolkov A; Dube J; Zhang Y; Zhang JS; Wang E; Dutta SK; Schmitt DM; Giles FJ; Kozikowski AP; Mazar AP; Mukhopadhyay D; Billadeau DD
    Clin Cancer Res; 2019 Nov; 25(21):6452-6462. PubMed ID: 31533931
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Depletion of ATR selectively sensitizes ATM-deficient human mammary epithelial cells to ionizing radiation and DNA-damaging agents.
    Cui Y; Palii SS; Innes CL; Paules RS
    Cell Cycle; 2014; 13(22):3541-50. PubMed ID: 25483091
    [TBL] [Abstract][Full Text] [Related]  

  • 23. The novel ATR inhibitor VE-821 increases sensitivity of pancreatic cancer cells to radiation and chemotherapy.
    Prevo R; Fokas E; Reaper PM; Charlton PA; Pollard JR; McKenna WG; Muschel RJ; Brunner TB
    Cancer Biol Ther; 2012 Sep; 13(11):1072-81. PubMed ID: 22825331
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Sulfoximines as ATR inhibitors: Analogs of VE-821.
    Hendriks CMM; Hartkamp J; Wiezorek S; Steinkamp AD; Rossetti G; Lüscher B; Bolm C
    Bioorg Med Chem Lett; 2017 Jun; 27(12):2659-2662. PubMed ID: 28479198
    [TBL] [Abstract][Full Text] [Related]  

  • 25. The antiproliferative effects of ataxia-telangiectasia mutated and ATM- and Rad3-related inhibitions and their enhancements with the cytotoxicity of DNA damaging agents in cholangiocarcinoma cells.
    Moolmuang B; Ruchirawat M
    J Pharm Pharmacol; 2021 Mar; 73(1):40-51. PubMed ID: 33791808
    [TBL] [Abstract][Full Text] [Related]  

  • 26. BENC-511, a novel PI3K inhibitor, suppresses metastasis of non-small cell lung cancer cells by modulating β-catenin/ZEB1 regulatory loop.
    Zhang Q; Zhou L; Guan Y; Cheng Y; Han X
    Chem Biol Interact; 2018 Oct; 294():18-27. PubMed ID: 30125547
    [TBL] [Abstract][Full Text] [Related]  

  • 27. S-phase sensing of DNA-protein crosslinks triggers TopBP1-independent ATR activation and p53-mediated cell death by formaldehyde.
    Wong VC; Cash HL; Morse JL; Lu S; Zhitkovich A
    Cell Cycle; 2012 Jul; 11(13):2526-37. PubMed ID: 22722496
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Radio-sensitizing effects of VE-821 and beyond: Distinct phosphoproteomic and metabolomic changes after ATR inhibition in irradiated MOLT-4 cells.
    Šalovská B; Janečková H; Fabrik I; Karlíková R; Čecháková L; Ondrej M; Link M; Friedecký D; Tichý A
    PLoS One; 2018; 13(7):e0199349. PubMed ID: 30001349
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Ultrasound activates ataxia telangiectasia mutated- and rad3-related (ATR)-checkpoint kinase 1 (Chk1) pathway in human leukemia Jurkat cells.
    Furusawa Y; Iizumi T; Fujiwara Y; Hassan MA; Tabuchi Y; Nomura T; Kondo T
    Ultrason Sonochem; 2012 Nov; 19(6):1246-51. PubMed ID: 22571845
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Chk1 phosphorylated at serine345 is a predictor of early local recurrence and radio-resistance in breast cancer.
    Alsubhi N; Middleton F; Abdel-Fatah TM; Stephens P; Doherty R; Arora A; Moseley PM; Chan SY; Aleskandarany MA; Green AR; Rakha EA; Ellis IO; Martin SG; Curtin NJ; Madhusudan S
    Mol Oncol; 2016 Feb; 10(2):213-23. PubMed ID: 26459098
    [TBL] [Abstract][Full Text] [Related]  

  • 31. The role of epithelial-mesenchymal transition drivers ZEB1 and ZEB2 in mediating docetaxel-resistant prostate cancer.
    Hanrahan K; O'Neill A; Prencipe M; Bugler J; Murphy L; Fabre A; Puhr M; Culig Z; Murphy K; Watson RW
    Mol Oncol; 2017 Mar; 11(3):251-265. PubMed ID: 28133913
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Long Non-Coding RNA ZEB1-Antisense 1 Affects Cell Migration and Invasion of Cervical Cancer by Regulating Epithelial-Mesenchymal Transition via the p38MAPK Signaling Pathway.
    Gan L; Chen Y; Liu H; Ju WH
    Gynecol Obstet Invest; 2019; 84(2):136-144. PubMed ID: 30253398
    [TBL] [Abstract][Full Text] [Related]  

  • 33. S-phase-dependent p50/NF-кB1 phosphorylation in response to ATR and replication stress acts to maintain genomic stability.
    Crawley CD; Kang S; Bernal GM; Wahlstrom JS; Voce DJ; Cahill KE; Garofalo A; Raleigh DR; Weichselbaum RR; Yamini B
    Cell Cycle; 2015; 14(4):566-76. PubMed ID: 25590437
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Targeting ATR in vivo using the novel inhibitor VE-822 results in selective sensitization of pancreatic tumors to radiation.
    Fokas E; Prevo R; Pollard JR; Reaper PM; Charlton PA; Cornelissen B; Vallis KA; Hammond EM; Olcina MM; Gillies McKenna W; Muschel RJ; Brunner TB
    Cell Death Dis; 2012 Dec; 3(12):e441. PubMed ID: 23222511
    [TBL] [Abstract][Full Text] [Related]  

  • 35. IL-13/STAT6 signaling plays a critical role in the epithelial-mesenchymal transition of colorectal cancer cells.
    Cao H; Zhang J; Liu H; Wan L; Zhang H; Huang Q; Xu E; Lai M
    Oncotarget; 2016 Sep; 7(38):61183-61198. PubMed ID: 27533463
    [TBL] [Abstract][Full Text] [Related]  

  • 36. ATR inhibition rewires cellular signaling networks induced by replication stress.
    Wagner SA; Oehler H; Voigt A; Dalic D; Freiwald A; Serve H; Beli P
    Proteomics; 2016 Feb; 16(3):402-16. PubMed ID: 26572502
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Inhibition of Wee1 sensitizes AML cells to ATR inhibitor VE-822-induced DNA damage and apoptosis.
    Qi W; Xu X; Wang M; Li X; Wang C; Sun L; Zhao D; Sun L
    Biochem Pharmacol; 2019 Jun; 164():273-282. PubMed ID: 31014753
    [TBL] [Abstract][Full Text] [Related]  

  • 38. ZEB1 modulates endometrial receptivity through epithelial-mesenchymal transition in endometrial epithelial cells in vitro.
    Ran J; Yang HH; Huang HP; Huang HL; Xu Z; Zhang W; Wang ZX
    Biochem Biophys Res Commun; 2020 May; 525(3):699-705. PubMed ID: 32139122
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Thymoquinone Inhibits the Migration and Invasive Characteristics of Cervical Cancer Cells SiHa and CaSki In Vitro by Targeting Epithelial to Mesenchymal Transition Associated Transcription Factors Twist1 and Zeb1.
    Li J; Khan MA; Wei C; Cheng J; Chen H; Yang L; Ijaz I; Fu J
    Molecules; 2017 Dec; 22(12):. PubMed ID: 29207526
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Gli1 protein regulates the S-phase checkpoint in tumor cells via Bid protein, and its inhibition sensitizes to DNA topoisomerase 1 inhibitors.
    Tripathi K; Mani C; Barnett R; Nalluri S; Bachaboina L; Rocconi RP; Athar M; Owen LB; Palle K
    J Biol Chem; 2014 Nov; 289(45):31513-25. PubMed ID: 25253693
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 21.