318 related articles for article (PubMed ID: 29158492)
1. Structural basis for the assembly of the Ragulator-Rag GTPase complex.
Yonehara R; Nada S; Nakai T; Nakai M; Kitamura A; Ogawa A; Nakatsumi H; Nakayama KI; Li S; Standley DM; Yamashita E; Nakagawa A; Okada M
Nat Commun; 2017 Nov; 8(1):1625. PubMed ID: 29158492
[TBL] [Abstract][Full Text] [Related]
2. Structural basis for Ragulator functioning as a scaffold in membrane-anchoring of Rag GTPases and mTORC1.
Zhang T; Wang R; Wang Z; Wang X; Wang F; Ding J
Nat Commun; 2017 Nov; 8(1):1394. PubMed ID: 29123114
[TBL] [Abstract][Full Text] [Related]
3. Hybrid Structure of the RagA/C-Ragulator mTORC1 Activation Complex.
Su MY; Morris KL; Kim DJ; Fu Y; Lawrence R; Stjepanovic G; Zoncu R; Hurley JH
Mol Cell; 2017 Dec; 68(5):835-846.e3. PubMed ID: 29107538
[TBL] [Abstract][Full Text] [Related]
4. Genetic dissection of Ragulator structure and function in amino acid-dependent regulation of mTORC1.
Nada S; Okada M
J Biochem; 2020 Dec; 168(6):621-632. PubMed ID: 32653916
[TBL] [Abstract][Full Text] [Related]
5. Disruption of the Rag-Ragulator Complex by c17orf59 Inhibits mTORC1.
Schweitzer LD; Comb WC; Bar-Peled L; Sabatini DM
Cell Rep; 2015 Sep; 12(9):1445-55. PubMed ID: 26299971
[TBL] [Abstract][Full Text] [Related]
6. Ragulator and SLC38A9 activate the Rag GTPases through noncanonical GEF mechanisms.
Shen K; Sabatini DM
Proc Natl Acad Sci U S A; 2018 Sep; 115(38):9545-9550. PubMed ID: 30181260
[TBL] [Abstract][Full Text] [Related]
7. A nutrient-induced affinity switch controls mTORC1 activation by its Rag GTPase-Ragulator lysosomal scaffold.
Lawrence RE; Cho KF; Rappold R; Thrun A; Tofaute M; Kim DJ; Moldavski O; Hurley JH; Zoncu R
Nat Cell Biol; 2018 Sep; 20(9):1052-1063. PubMed ID: 30061680
[TBL] [Abstract][Full Text] [Related]
8. Rag GTPase in amino acid signaling.
Kim J; Kim E
Amino Acids; 2016 Apr; 48(4):915-928. PubMed ID: 26781224
[TBL] [Abstract][Full Text] [Related]
9. Amino acids activate mammalian target of rapamycin (mTOR) complex 1 without changing Rag GTPase guanyl nucleotide charging.
Oshiro N; Rapley J; Avruch J
J Biol Chem; 2014 Jan; 289(5):2658-74. PubMed ID: 24337580
[TBL] [Abstract][Full Text] [Related]
10. Structural mechanism of a Rag GTPase activation checkpoint by the lysosomal folliculin complex.
Lawrence RE; Fromm SA; Fu Y; Yokom AL; Kim DJ; Thelen AM; Young LN; Lim CY; Samelson AJ; Hurley JH; Zoncu R
Science; 2019 Nov; 366(6468):971-977. PubMed ID: 31672913
[TBL] [Abstract][Full Text] [Related]
11. Metabolism. Differential regulation of mTORC1 by leucine and glutamine.
Jewell JL; Kim YC; Russell RC; Yu FX; Park HW; Plouffe SW; Tagliabracci VS; Guan KL
Science; 2015 Jan; 347(6218):194-8. PubMed ID: 25567907
[TBL] [Abstract][Full Text] [Related]
12. Amino Acid-Dependent mTORC1 Regulation by the Lysosomal Membrane Protein SLC38A9.
Jung J; Genau HM; Behrends C
Mol Cell Biol; 2015 Jul; 35(14):2479-94. PubMed ID: 25963655
[TBL] [Abstract][Full Text] [Related]
13. Cryo-EM structures of the human GATOR1-Rag-Ragulator complex reveal a spatial-constraint regulated GAP mechanism.
Egri SB; Ouch C; Chou HT; Yu Z; Song K; Xu C; Shen K
Mol Cell; 2022 May; 82(10):1836-1849.e5. PubMed ID: 35338845
[TBL] [Abstract][Full Text] [Related]
14. RagA, an mTORC1 activator, interacts with a hedgehog signaling protein, WDR35/IFT121.
Sekiguchi T; Furuno N; Ishii T; Hirose E; Sekiguchi F; Wang Y; Kobayashi H
Genes Cells; 2019 Feb; 24(2):151-161. PubMed ID: 30570184
[TBL] [Abstract][Full Text] [Related]
15. Architecture of human Rag GTPase heterodimers and their complex with mTORC1.
Anandapadamanaban M; Masson GR; Perisic O; Berndt A; Kaufman J; Johnson CM; Santhanam B; Rogala KB; Sabatini DM; Williams RL
Science; 2019 Oct; 366(6462):203-210. PubMed ID: 31601764
[TBL] [Abstract][Full Text] [Related]
16. Glutamine and asparagine activate mTORC1 independently of Rag GTPases.
Meng D; Yang Q; Wang H; Melick CH; Navlani R; Frank AR; Jewell JL
J Biol Chem; 2020 Mar; 295(10):2890-2899. PubMed ID: 32019866
[TBL] [Abstract][Full Text] [Related]
17. Architecture of the human GATOR1 and GATOR1-Rag GTPases complexes.
Shen K; Huang RK; Brignole EJ; Condon KJ; Valenstein ML; Chantranupong L; Bomaliyamu A; Choe A; Hong C; Yu Z; Sabatini DM
Nature; 2018 Apr; 556(7699):64-69. PubMed ID: 29590090
[TBL] [Abstract][Full Text] [Related]
18. Structural basis for the docking of mTORC1 on the lysosomal surface.
Rogala KB; Gu X; Kedir JF; Abu-Remaileh M; Bianchi LF; Bottino AMS; Dueholm R; Niehaus A; Overwijn D; Fils AP; Zhou SX; Leary D; Laqtom NN; Brignole EJ; Sabatini DM
Science; 2019 Oct; 366(6464):468-475. PubMed ID: 31601708
[TBL] [Abstract][Full Text] [Related]
19. Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids.
Sancak Y; Bar-Peled L; Zoncu R; Markhard AL; Nada S; Sabatini DM
Cell; 2010 Apr; 141(2):290-303. PubMed ID: 20381137
[TBL] [Abstract][Full Text] [Related]
20. Regulation of mTORC1 by the Rag GTPases.
Lama-Sherpa TD; Jeong MH; Jewell JL
Biochem Soc Trans; 2023 Apr; 51(2):655-664. PubMed ID: 36929165
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
