BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

487 related articles for article (PubMed ID: 29162437)

  • 1. Mouse Model of Alagille Syndrome and Mechanisms of Jagged1 Missense Mutations.
    Andersson ER; Chivukula IV; Hankeova S; Sjöqvist M; Tsoi YL; Ramsköld D; Masek J; Elmansuri A; Hoogendoorn A; Vazquez E; Storvall H; Netušilová J; Huch M; Fischler B; Ellis E; Contreras A; Nemeth A; Chien KC; Clevers H; Sandberg R; Bryja V; Lendahl U
    Gastroenterology; 2018 Mar; 154(4):1080-1095. PubMed ID: 29162437
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A mouse model of Alagille syndrome: Notch2 as a genetic modifier of Jag1 haploinsufficiency.
    McCright B; Lozier J; Gridley T
    Development; 2002 Feb; 129(4):1075-82. PubMed ID: 11861489
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Alagille syndrome mutation update: Comprehensive overview of JAG1 and NOTCH2 mutation frequencies and insight into missense variant classification.
    Gilbert MA; Bauer RC; Rajagopalan R; Grochowski CM; Chao G; McEldrew D; Nassur JA; Rand EB; Krock BL; Kamath BM; Krantz ID; Piccoli DA; Loomes KM; Spinner NB
    Hum Mutat; 2019 Dec; 40(12):2197-2220. PubMed ID: 31343788
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Spatially segregated defects and IGF1-responsiveness of hilar and peripheral biliary organoids from a model of Alagille syndrome.
    Iqbal A; Van Hul N; Belicova L; Corbat AA; Hankeova S; Andersson ER
    Liver Int; 2024 Feb; 44(2):541-558. PubMed ID: 38014627
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Bile duct proliferation in Jag1/fringe heterozygous mice identifies candidate modifiers of the Alagille syndrome hepatic phenotype.
    Ryan MJ; Bales C; Nelson A; Gonzalez DM; Underkoffler L; Segalov M; Wilson-Rawls J; Cole SE; Moran JL; Russo P; Spinner NB; Kusumi K; Loomes KM
    Hepatology; 2008 Dec; 48(6):1989-97. PubMed ID: 19026002
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Bile duct proliferation in liver-specific Jag1 conditional knockout mice: effects of gene dosage.
    Loomes KM; Russo P; Ryan M; Nelson A; Underkoffler L; Glover C; Fu H; Gridley T; Kaestner KH; Oakey RJ
    Hepatology; 2007 Feb; 45(2):323-30. PubMed ID: 17366661
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sox9 Is a Modifier of the Liver Disease Severity in a Mouse Model of Alagille Syndrome.
    Adams JM; Huppert KA; Castro EC; Lopez MF; Niknejad N; Subramanian S; Zarrin-Khameh N; Finegold MJ; Huppert SS; Jafar-Nejad H
    Hepatology; 2020 Apr; 71(4):1331-1349. PubMed ID: 31469182
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Clinical features, outcomes, and genetic analysis in Korean children with Alagille syndrome.
    Cho JM; Oh SH; Kim HJ; Kim JS; Kim KM; Kim GH; Yu E; Lee BH; Yoo HW
    Pediatr Int; 2015 Aug; 57(4):552-7. PubMed ID: 25676721
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Renal involvement and the role of Notch signalling in Alagille syndrome.
    Kamath BM; Spinner NB; Rosenblum ND
    Nat Rev Nephrol; 2013 Jul; 9(7):409-18. PubMed ID: 23752887
    [TBL] [Abstract][Full Text] [Related]  

  • 10. NOTCH2 mutations in Alagille syndrome.
    Kamath BM; Bauer RC; Loomes KM; Chao G; Gerfen J; Hutchinson A; Hardikar W; Hirschfield G; Jara P; Krantz ID; Lapunzina P; Leonard L; Ling S; Ng VL; Hoang PL; Piccoli DA; Spinner NB
    J Med Genet; 2012 Feb; 49(2):138-44. PubMed ID: 22209762
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Intrahepatic cholangiocyte regeneration from an Fgf-dependent extrahepatic progenitor niche in a zebrafish model of Alagille Syndrome.
    Zhao C; Lancman JJ; Yang Y; Gates KP; Cao D; Barske L; Matalonga J; Pan X; He J; Graves A; Huisken J; Chen C; Dong PDS
    Hepatology; 2022 Mar; 75(3):567-583. PubMed ID: 34569629
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ASO silencing of a glycosyltransferase, Poglut1 , improves the liver phenotypes in mouse models of Alagille syndrome.
    Niknejad N; Fox D; Burwinkel JL; Zarrin-Khameh N; Cho S; Soriano A; Cast AE; Lopez MF; Huppert KA; Rigo F; Huppert SS; Jafar-Nejad P; Jafar-Nejad H
    Hepatology; 2023 Nov; 78(5):1337-1351. PubMed ID: 37021797
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Jagged1 in the portal vein mesenchyme regulates intrahepatic bile duct development: insights into Alagille syndrome.
    Hofmann JJ; Zovein AC; Koh H; Radtke F; Weinmaster G; Iruela-Arispe ML
    Development; 2010 Dec; 137(23):4061-72. PubMed ID: 21062863
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Notch signaling regulates bile duct morphogenesis in mice.
    Lozier J; McCright B; Gridley T
    PLoS One; 2008 Mar; 3(3):e1851. PubMed ID: 18365007
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The role of notch signaling in the development of intrahepatic bile ducts.
    Kodama Y; Hijikata M; Kageyama R; Shimotohno K; Chiba T
    Gastroenterology; 2004 Dec; 127(6):1775-86. PubMed ID: 15578515
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Alagille Syndrome.
    Mitchell E; Gilbert M; Loomes KM
    Clin Liver Dis; 2018 Nov; 22(4):625-641. PubMed ID: 30266153
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cranial neural crest ablation of Jagged1 recapitulates the craniofacial phenotype of Alagille syndrome patients.
    Humphreys R; Zheng W; Prince LS; Qu X; Brown C; Loomes K; Huppert SS; Baldwin S; Goudy S
    Hum Mol Genet; 2012 Mar; 21(6):1374-83. PubMed ID: 22156581
    [TBL] [Abstract][Full Text] [Related]  

  • 18. NOTCH2 mutations cause Alagille syndrome, a heterogeneous disorder of the notch signaling pathway.
    McDaniell R; Warthen DM; Sanchez-Lara PA; Pai A; Krantz ID; Piccoli DA; Spinner NB
    Am J Hum Genet; 2006 Jul; 79(1):169-73. PubMed ID: 16773578
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The role of Notch receptor expression in bile duct development and disease.
    Flynn DM; Nijjar S; Hubscher SG; de Goyet Jde V; Kelly DA; Strain AJ; Crosby HA
    J Pathol; 2004 Sep; 204(1):55-64. PubMed ID: 15307138
    [TBL] [Abstract][Full Text] [Related]  

  • 20. DUCT reveals architectural mechanisms contributing to bile duct recovery in a mouse model for Alagille syndrome.
    Hankeova S; Salplachta J; Zikmund T; Kavkova M; Van Hul N; Brinek A; Smekalova V; Laznovsky J; Dawit F; Jaros J; Bryja V; Lendahl U; Ellis E; Nemeth A; Fischler B; Hannezo E; Kaiser J; Andersson ER
    Elife; 2021 Feb; 10():. PubMed ID: 33635272
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 25.