183 related articles for article (PubMed ID: 29162643)
1. Identification of an Oleanane-Type Triterpene Hedragonic Acid as a Novel Farnesoid X Receptor Ligand with Liver Protective Effects and Anti-inflammatory Activity.
Lu Y; Zheng W; Lin S; Guo F; Zhu Y; Wei Y; Liu X; Jin S; Jin L; Li Y
Mol Pharmacol; 2018 Feb; 93(2):63-72. PubMed ID: 29162643
[TBL] [Abstract][Full Text] [Related]
2. Targeting the transsulfuration-H2S pathway by FXR and GPBAR1 ligands in the treatment of portal hypertension.
Fiorucci S; Distrutti E
Pharmacol Res; 2016 Sep; 111():749-756. PubMed ID: 27475883
[TBL] [Abstract][Full Text] [Related]
3. Investigation on bile acid receptor regulators. Discovery of cholanoic acid derivatives with dual G-protein coupled bile acid receptor 1 (GPBAR1) antagonistic and farnesoid X receptor (FXR) modulatory activity.
Sepe V; Renga B; Festa C; Finamore C; Masullo D; Carino A; Cipriani S; Distrutti E; Fiorucci S; Zampella A
Steroids; 2016 Jan; 105():59-67. PubMed ID: 26607331
[TBL] [Abstract][Full Text] [Related]
4. Yangonin protects against cholestasis and hepatotoxity via activation of farnesoid X receptor in vivo and in vitro.
Gao X; Fu T; Wang C; Ning C; Liu K; Liu Z; Sun H; Ma X; Huo X; Yang X; Zou M; Meng Q
Toxicol Appl Pharmacol; 2018 Jun; 348():105-116. PubMed ID: 29660435
[TBL] [Abstract][Full Text] [Related]
5. Chemistry and Pharmacology of GPBAR1 and FXR Selective Agonists, Dual Agonists, and Antagonists.
De Marino S; Festa C; Sepe V; Zampella A
Handb Exp Pharmacol; 2019; 256():137-165. PubMed ID: 31201554
[TBL] [Abstract][Full Text] [Related]
6. Structural Insight into the Binding Mode of FXR and GPBAR1 Modulators.
Di Leva FS; Di Marino D; Limongelli V
Handb Exp Pharmacol; 2019; 256():111-136. PubMed ID: 31161298
[TBL] [Abstract][Full Text] [Related]
7. Navigation in bile acid chemical space: discovery of novel FXR and GPBAR1 ligands.
Finamore C; Festa C; Renga B; Sepe V; Carino A; Masullo D; Biagioli M; Marchianò S; Capolupo A; Monti MC; Fiorucci S; Zampella A
Sci Rep; 2016 Jul; 6():29320. PubMed ID: 27381677
[TBL] [Abstract][Full Text] [Related]
8. 3β-Isoobeticholic acid efficiently activates the farnesoid X receptor (FXR) due to its epimerization to 3α-epimer by hepatic metabolism.
Stefela A; Kaspar M; Drastik M; Holas O; Hroch M; Smutny T; Skoda J; Hutníková M; Pandey AV; Micuda S; Kudova E; Pavek P
J Steroid Biochem Mol Biol; 2020 Sep; 202():105702. PubMed ID: 32505574
[TBL] [Abstract][Full Text] [Related]
9. Development of bile acid activated receptors hybrid molecules for the treatment of inflammatory and metabolic disorders.
Fiorucci S; Sepe V; Biagioli M; Fiorillo B; Rapacciuolo P; Distrutti E; Zampella A
Biochem Pharmacol; 2023 Oct; 216():115776. PubMed ID: 37659739
[TBL] [Abstract][Full Text] [Related]
10. Defective Bile Acid Signaling Promotes Vascular Dysfunction, Supporting a Role for G-Protein Bile Acid Receptor 1/Farnesoid X Receptor Agonism and Statins in the Treatment of Nonalcoholic Fatty Liver Disease.
Marchianò S; Biagioli M; Bordoni M; Morretta E; Di Giorgio C; Vellecco V; Roselli R; Bellini R; Massa C; Cari L; Urbani G; Ricci P; Monti MC; Giordano A; Brancaleone V; Bucci M; Zampella A; Distrutti E; Cieri E; Cirino G; Fiorucci S
J Am Heart Assoc; 2023 Dec; 12(23):e031241. PubMed ID: 37996988
[TBL] [Abstract][Full Text] [Related]
11. Bile acid modulators for the treatment of nonalcoholic steatohepatitis (NASH).
Fiorucci S; Biagioli M; Sepe V; Zampella A; Distrutti E
Expert Opin Investig Drugs; 2020 Jun; 29(6):623-632. PubMed ID: 32552182
[TBL] [Abstract][Full Text] [Related]
12. Structural insight into the molecular mechanism of cilofexor binding to the farnesoid X receptor.
Jiang L; Liu X; Wei H; Dai S; Qu L; Chen X; Guo M; Chen Y
Biochem Biophys Res Commun; 2022 Mar; 595():1-6. PubMed ID: 35091108
[TBL] [Abstract][Full Text] [Related]
13. Protective effects of SRT1720 via the HNF1α/FXR signalling pathway and anti-inflammatory mechanisms in mice with estrogen-induced cholestatic liver injury.
Yu L; Liu X; Li X; Yuan Z; Yang H; Zhang L; Jiang Z
Toxicol Lett; 2016 Dec; 264():1-11. PubMed ID: 27818225
[TBL] [Abstract][Full Text] [Related]
14. Impaired Itching Perception in Murine Models of Cholestasis Is Supported by Dysregulation of GPBAR1 Signaling.
Cipriani S; Renga B; D'Amore C; Simonetti M; De Tursi AA; Carino A; Monti MC; Sepe V; Zampella A; Fiorucci S
PLoS One; 2015; 10(7):e0129866. PubMed ID: 26177448
[TBL] [Abstract][Full Text] [Related]
15. Transcriptome Analysis of Dual FXR and GPBAR1 Agonism in Rodent Model of NASH Reveals Modulation of Lipid Droplets Formation.
Carino A; Marchianò S; Biagioli M; Fiorucci C; Zampella A; Monti MC; Morretta E; Bordoni M; Di Giorgio C; Roselli R; Ricci P; Distrutti E; Fiorucci S
Nutrients; 2019 May; 11(5):. PubMed ID: 31117231
[TBL] [Abstract][Full Text] [Related]
16. Terpenoids from the stems of Celastrus hindsii and their anti-RSV activities.
Luo D; Xiong S; Li QG; Jiang L; Niu QW; He LJ; Li YL; Zhang YB; Wang GC
Fitoterapia; 2018 Oct; 130():118-124. PubMed ID: 30165177
[TBL] [Abstract][Full Text] [Related]
17. Structural basis for the hepatoprotective effects of antihypertensive 1,4-dihydropyridine drugs.
Wei Y; Lu Y; Zhu Y; Zheng W; Guo F; Yao B; Xu S; Wang Y; Jin L; Li Y
Biochim Biophys Acta Gen Subj; 2018 Oct; 1862(10):2261-2270. PubMed ID: 30048741
[TBL] [Abstract][Full Text] [Related]
18. Alisol B 23-acetate protects against ANIT-induced hepatotoxity and cholestasis, due to FXR-mediated regulation of transporters and enzymes involved in bile acid homeostasis.
Meng Q; Chen XL; Wang CY; Liu Q; Sun HJ; Sun PY; Huo XK; Liu ZH; Yao JH; Liu KX
Toxicol Appl Pharmacol; 2015 Mar; 283(3):178-86. PubMed ID: 25655198
[TBL] [Abstract][Full Text] [Related]
19. The bile acid activated receptors GPBAR1 and FXR exert antagonistic effects on autophagy.
Carino A; Marchianò S; Biagioli M; Scarpelli P; Bordoni M; Di Giorgio C; Roselli R; Fiorucci C; Monti MC; Distrutti E; Zampella A; Fiorucci S
FASEB J; 2021 Jan; 35(1):e21271. PubMed ID: 33368684
[TBL] [Abstract][Full Text] [Related]
20. Discovery of Farnesoid X Receptor Antagonists Based on a Library of Oleanolic Acid 3-O-Esters through Diverse Substituent Design and Molecular Docking Methods.
Wang SR; Xu T; Deng K; Wong CW; Liu J; Fang WS
Molecules; 2017 Apr; 22(5):. PubMed ID: 28445411
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
