294 related articles for article (PubMed ID: 29167270)
1. UbiA prenyltransferase domain-containing protein-1 modulates HMG-CoA reductase degradation to coordinate synthesis of sterol and nonsterol isoprenoids.
Schumacher MM; Jun DJ; Johnson BM; DeBose-Boyd RA
J Biol Chem; 2018 Jan; 293(1):312-323. PubMed ID: 29167270
[TBL] [Abstract][Full Text] [Related]
2. Geranylgeranyl-regulated transport of the prenyltransferase UBIAD1 between membranes of the ER and Golgi.
Schumacher MM; Jun DJ; Jo Y; Seemann J; DeBose-Boyd RA
J Lipid Res; 2016 Jul; 57(7):1286-99. PubMed ID: 27121042
[TBL] [Abstract][Full Text] [Related]
3. Schnyder corneal dystrophy-associated UBIAD1 is defective in MK-4 synthesis and resists autophagy-mediated degradation.
Jun DJ; Schumacher MM; Hwang S; Kinch LN; Grishin NV; DeBose-Boyd RA
J Lipid Res; 2020 May; 61(5):746-757. PubMed ID: 32188638
[TBL] [Abstract][Full Text] [Related]
4. Posttranslational Regulation of HMG CoA Reductase, the Rate-Limiting Enzyme in Synthesis of Cholesterol.
Schumacher MM; DeBose-Boyd RA
Annu Rev Biochem; 2021 Jun; 90():659-679. PubMed ID: 34153214
[TBL] [Abstract][Full Text] [Related]
5. Type 1 polyisoprenoid diphosphate phosphatase modulates geranylgeranyl-mediated control of HMG CoA reductase and UBIAD1.
Elsabrouty R; Jo Y; Hwang S; Jun DJ; DeBose-Boyd RA
Elife; 2021 Nov; 10():. PubMed ID: 34842525
[TBL] [Abstract][Full Text] [Related]
6. Post-Translational Regulation of HMG CoA Reductase.
Jo Y; DeBose-Boyd RA
Cold Spring Harb Perspect Biol; 2022 Dec; 14(12):. PubMed ID: 35940903
[TBL] [Abstract][Full Text] [Related]
7. Schnyder corneal dystrophy-associated UBIAD1 inhibits ER-associated degradation of HMG CoA reductase in mice.
Jo Y; Hamilton JS; Hwang S; Garland K; Smith GA; Su S; Fuentes I; Neelam S; Thompson BM; McDonald JG; DeBose-Boyd RA
Elife; 2019 Feb; 8():. PubMed ID: 30785396
[TBL] [Abstract][Full Text] [Related]
8. The prenyltransferase UBIAD1 is the target of geranylgeraniol in degradation of HMG CoA reductase.
Schumacher MM; Elsabrouty R; Seemann J; Jo Y; DeBose-Boyd RA
Elife; 2015 Mar; 4():. PubMed ID: 25742604
[TBL] [Abstract][Full Text] [Related]
9. Underlying mechanisms for sterol-induced ubiquitination and ER-associated degradation of HMG CoA reductase.
Johnson BM; DeBose-Boyd RA
Semin Cell Dev Biol; 2018 Sep; 81():121-128. PubMed ID: 29107682
[TBL] [Abstract][Full Text] [Related]
10. Schnyder corneal dystrophy-associated UBIAD1 mutations cause corneal cholesterol accumulation by stabilizing HMG-CoA reductase.
Jiang SY; Tang JJ; Xiao X; Qi W; Wu S; Jiang C; Hong J; Xu J; Song BL; Luo J
PLoS Genet; 2019 Jul; 15(7):e1008289. PubMed ID: 31323021
[TBL] [Abstract][Full Text] [Related]
11. Synthesis, function, and regulation of sterol and nonsterol isoprenoids.
Faulkner R; Jo Y
Front Mol Biosci; 2022; 9():1006822. PubMed ID: 36275615
[TBL] [Abstract][Full Text] [Related]
12. Enhanced ER-associated degradation of HMG CoA reductase causes embryonic lethality associated with
Jo Y; Kim SS; Garland K; Fuentes I; DiCarlo LM; Ellis JL; Fu X; Booth SL; Evers BM; DeBose-Boyd RA
Elife; 2020 Mar; 9():. PubMed ID: 32118581
[TBL] [Abstract][Full Text] [Related]
13. Insulin-induced gene protein (INSIG)-dependent sterol regulation of Hmg2 endoplasmic reticulum-associated degradation (ERAD) in yeast.
Theesfeld CL; Hampton RY
J Biol Chem; 2013 Mar; 288(12):8519-8530. PubMed ID: 23306196
[TBL] [Abstract][Full Text] [Related]
14. Functional study of SCCD pathogenic gene
Xie J; Li L
Mol Med Rep; 2021 Oct; 24(4):. PubMed ID: 34368857
[TBL] [Abstract][Full Text] [Related]
15. Regulated degradation of HMG CoA reductase requires conformational changes in sterol-sensing domain.
Chen H; Qi X; Faulkner RA; Schumacher MM; Donnelly LM; DeBose-Boyd RA; Li X
Nat Commun; 2022 Jul; 13(1):4273. PubMed ID: 35879350
[TBL] [Abstract][Full Text] [Related]
16. The UBIAD1 prenyltransferase links menaquinone-4 [corrected] synthesis to cholesterol metabolic enzymes.
Nickerson ML; Bosley AD; Weiss JS; Kostiha BN; Hirota Y; Brandt W; Esposito D; Kinoshita S; Wessjohann L; Morham SG; Andresson T; Kruth HS; Okano T; Dean M
Hum Mutat; 2013 Feb; 34(2):317-29. PubMed ID: 23169578
[TBL] [Abstract][Full Text] [Related]
17. Direct binding to sterols accelerates endoplasmic reticulum-associated degradation of HMG CoA reductase.
Faulkner RA; Yang Y; Tsien J; Qin T; DeBose-Boyd RA
Proc Natl Acad Sci U S A; 2024 Feb; 121(7):e2318822121. PubMed ID: 38319967
[TBL] [Abstract][Full Text] [Related]
18. Sequential actions of the AAA-ATPase valosin-containing protein (VCP)/p97 and the proteasome 19 S regulatory particle in sterol-accelerated, endoplasmic reticulum (ER)-associated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
Morris LL; Hartman IZ; Jun DJ; Seemann J; DeBose-Boyd RA
J Biol Chem; 2014 Jul; 289(27):19053-66. PubMed ID: 24860107
[TBL] [Abstract][Full Text] [Related]
19. An autonomous, but INSIG-modulated, role for the sterol sensing domain in mallostery-regulated ERAD of yeast HMG-CoA reductase.
Wangeline MA; Hampton RY
J Biol Chem; 2021; 296():100063. PubMed ID: 33184059
[TBL] [Abstract][Full Text] [Related]
20. Lipid-regulated degradation of HMG-CoA reductase and Insig-1 through distinct mechanisms in insect cells.
Faulkner RA; Nguyen AD; Jo Y; DeBose-Boyd RA
J Lipid Res; 2013 Apr; 54(4):1011-22. PubMed ID: 23403031
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]