410 related articles for article (PubMed ID: 29168755)
1. Regulation of G2/M Transition by Inhibition of WEE1 and PKMYT1 Kinases.
Schmidt M; Rohe A; Platzer C; Najjar A; Erdmann F; Sippl W
Molecules; 2017 Nov; 22(12):. PubMed ID: 29168755
[TBL] [Abstract][Full Text] [Related]
2. Mitotic progression becomes irreversible in prometaphase and collapses when Wee1 and Cdc25 are inhibited.
Potapova TA; Sivakumar S; Flynn JN; Li R; Gorbsky GJ
Mol Biol Cell; 2011 Apr; 22(8):1191-206. PubMed ID: 21325631
[TBL] [Abstract][Full Text] [Related]
3. Structural Basis of Wee Kinases Functionality and Inactivation by Diverse Small Molecule Inhibitors.
Zhu JY; Cuellar RA; Berndt N; Lee HE; Olesen SH; Martin MP; Jensen JT; Georg GI; Schönbrunn E
J Med Chem; 2017 Sep; 60(18):7863-7875. PubMed ID: 28792760
[TBL] [Abstract][Full Text] [Related]
4. Preclinical evaluation of the WEE1 inhibitor MK-1775 as single-agent anticancer therapy.
Guertin AD; Li J; Liu Y; Hurd MS; Schuller AG; Long B; Hirsch HA; Feldman I; Benita Y; Toniatti C; Zawel L; Fawell SE; Gilliland DG; Shumway SD
Mol Cancer Ther; 2013 Aug; 12(8):1442-52. PubMed ID: 23699655
[TBL] [Abstract][Full Text] [Related]
5. Targeting WEE1 Kinase in Cancer.
Matheson CJ; Backos DS; Reigan P
Trends Pharmacol Sci; 2016 Oct; 37(10):872-881. PubMed ID: 27427153
[TBL] [Abstract][Full Text] [Related]
6. Genome-wide CRISPR-Cas9 Screens Reveal Loss of Redundancy between PKMYT1 and WEE1 in Glioblastoma Stem-like Cells.
Toledo CM; Ding Y; Hoellerbauer P; Davis RJ; Basom R; Girard EJ; Lee E; Corrin P; Hart T; Bolouri H; Davison J; Zhang Q; Hardcastle J; Aronow BJ; Plaisier CL; Baliga NS; Moffat J; Lin Q; Li XN; Nam DH; Lee J; Pollard SM; Zhu J; Delrow JJ; Clurman BE; Olson JM; Paddison PJ
Cell Rep; 2015 Dec; 13(11):2425-2439. PubMed ID: 26673326
[TBL] [Abstract][Full Text] [Related]
7. A WEE1 family business: regulation of mitosis, cancer progression, and therapeutic target.
Ghelli Luserna di Rorà A; Cerchione C; Martinelli G; Simonetti G
J Hematol Oncol; 2020 Sep; 13(1):126. PubMed ID: 32958072
[TBL] [Abstract][Full Text] [Related]
8. Molecular Pathways: Targeting the Protein Kinase Wee1 in Cancer.
Geenen JJJ; Schellens JHM
Clin Cancer Res; 2017 Aug; 23(16):4540-4544. PubMed ID: 28442503
[TBL] [Abstract][Full Text] [Related]
9. Wee1 inhibition potentiates Wip1-dependent p53-negative tumor cell death during chemotherapy.
Clausse V; Goloudina AR; Uyanik B; Kochetkova EY; Richaud S; Fedorova OA; Hammann A; Bardou M; Barlev NA; Garrido C; Demidov ON
Cell Death Dis; 2016 Apr; 7(4):e2195. PubMed ID: 27077811
[TBL] [Abstract][Full Text] [Related]
10. Wee1 kinase as a target for cancer therapy.
Do K; Doroshow JH; Kummar S
Cell Cycle; 2013 Oct; 12(19):3159-64. PubMed ID: 24013427
[TBL] [Abstract][Full Text] [Related]
11. Abrogation of the G2 checkpoint by inhibition of Wee-1 kinase results in sensitization of p53-deficient tumor cells to DNA-damaging agents.
Leijen S; Beijnen JH; Schellens JH
Curr Clin Pharmacol; 2010 Aug; 5(3):186-91. PubMed ID: 20406171
[TBL] [Abstract][Full Text] [Related]
12. WEE1 kinase targeting combined with DNA-damaging cancer therapy catalyzes mitotic catastrophe.
De Witt Hamer PC; Mir SE; Noske D; Van Noorden CJ; Würdinger T
Clin Cancer Res; 2011 Jul; 17(13):4200-7. PubMed ID: 21562035
[TBL] [Abstract][Full Text] [Related]
13. Differential properties of mitosis-associated events following CHK1 and WEE1 inhibitor treatments in human tongue carcinoma cells.
Nojima H; Homma H; Onozato Y; Kaida A; Harada H; Miura M
Exp Cell Res; 2020 Jan; 386(2):111720. PubMed ID: 31738907
[TBL] [Abstract][Full Text] [Related]
14. Identification of PKMYT1 inhibitors by screening the GSK published protein kinase inhibitor set I and II.
Platzer C; Najjar A; Rohe A; Erdmann F; Sippl W; Schmidt M
Bioorg Med Chem; 2018 Aug; 26(14):4014-4024. PubMed ID: 29941193
[TBL] [Abstract][Full Text] [Related]
15. Computer-aided design, synthesis and biological characterization of novel inhibitors for PKMYT1.
Najjar A; Platzer C; Luft A; Aßmann CA; Elghazawy NH; Erdmann F; Sippl W; Schmidt M
Eur J Med Chem; 2019 Jan; 161():479-492. PubMed ID: 30388464
[TBL] [Abstract][Full Text] [Related]
16. Mutations of the LIM protein AJUBA mediate sensitivity of head and neck squamous cell carcinoma to treatment with cell-cycle inhibitors.
Zhang M; Singh R; Peng S; Mazumdar T; Sambandam V; Shen L; Tong P; Li L; Kalu NN; Pickering CR; Frederick M; Myers JN; Wang J; Johnson FM
Cancer Lett; 2017 Apr; 392():71-82. PubMed ID: 28126323
[TBL] [Abstract][Full Text] [Related]
17. Identification and characterization of human Wee1B, a new member of the Wee1 family of Cdk-inhibitory kinases.
Nakanishi M; Ando H; Watanabe N; Kitamura K; Ito K; Okayama H; Miyamoto T; Agui T; Sasaki M
Genes Cells; 2000 Oct; 5(10):839-47. PubMed ID: 11029659
[TBL] [Abstract][Full Text] [Related]
18. WEE1 kinase limits CDK activities to safeguard DNA replication and mitotic entry.
Elbæk CR; Petrosius V; Sørensen CS
Mutat Res; 2020; 819-820():111694. PubMed ID: 32120135
[TBL] [Abstract][Full Text] [Related]
19. Abrogating G₂/M checkpoint through WEE1 inhibition in combination with chemotherapy as a promising therapeutic approach for mesothelioma.
Indovina P; Marcelli E; Di Marzo D; Casini N; Forte IM; Giorgi F; Alfano L; Pentimalli F; Giordano A
Cancer Biol Ther; 2014 Apr; 15(4):380-8. PubMed ID: 24365782
[TBL] [Abstract][Full Text] [Related]
20. Combined inhibition of Chk1 and Wee1 as a new therapeutic strategy for mantle cell lymphoma.
Chilà R; Basana A; Lupi M; Guffanti F; Gaudio E; Rinaldi A; Cascione L; Restelli V; Tarantelli C; Bertoni F; Damia G; Carrassa L
Oncotarget; 2015 Feb; 6(5):3394-408. PubMed ID: 25428911
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
