BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

220 related articles for article (PubMed ID: 29170376)

  • 1. Cryo-EM structure of Saccharomyces cerevisiae target of rapamycin complex 2.
    Karuppasamy M; Kusmider B; Oliveira TM; Gaubitz C; Prouteau M; Loewith R; Schaffitzel C
    Nat Commun; 2017 Nov; 8(1):1729. PubMed ID: 29170376
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Molecular organization of target of rapamycin complex 2.
    Wullschleger S; Loewith R; Oppliger W; Hall MN
    J Biol Chem; 2005 Sep; 280(35):30697-704. PubMed ID: 16002396
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Analysis of the roles of phosphatidylinositol-4,5-
    Martinez Marshall MN; Emmerstorfer-Augustin A; Leskoske KL; Zhang LH; Li B; Thorner J
    Mol Biol Cell; 2019 Jun; 30(12):1555-1574. PubMed ID: 30969890
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Redesigning TOR Kinase to Explore the Structural Basis for TORC1 and TORC2 Assembly.
    Hill A; Niles B; Cuyegkeng A; Powers T
    Biomolecules; 2018 Jun; 8(2):. PubMed ID: 29865216
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Molecular Basis of the Rapamycin Insensitivity of Target Of Rapamycin Complex 2.
    Gaubitz C; Oliveira TM; Prouteau M; Leitner A; Karuppasamy M; Konstantinidou G; Rispal D; Eltschinger S; Robinson GC; Thore S; Aebersold R; Schaffitzel C; Loewith R
    Mol Cell; 2015 Jun; 58(6):977-88. PubMed ID: 26028537
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure of TOR and its complex with KOG1.
    Adami A; García-Alvarez B; Arias-Palomo E; Barford D; Llorca O
    Mol Cell; 2007 Aug; 27(3):509-16. PubMed ID: 17679098
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control.
    Loewith R; Jacinto E; Wullschleger S; Lorberg A; Crespo JL; Bonenfant D; Oppliger W; Jenoe P; Hall MN
    Mol Cell; 2002 Sep; 10(3):457-68. PubMed ID: 12408816
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Target of rapamycin complex 2 signals to downstream effector yeast protein kinase 2 (Ypk2) through adheres-voraciously-to-target-of-rapamycin-2 protein 1 (Avo1) in Saccharomyces cerevisiae.
    Liao HC; Chen MY
    J Biol Chem; 2012 Feb; 287(9):6089-99. PubMed ID: 22207764
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Ubiquitin regulates TORC1 in yeast Saccharomyces cerevisiae.
    Hu K; Guo S; Yan G; Yuan W; Zheng Y; Jiang Y
    Mol Microbiol; 2016 Apr; 100(2):303-14. PubMed ID: 26700129
    [TBL] [Abstract][Full Text] [Related]  

  • 10. TORC2 signaling is antagonized by protein phosphatase 2A and the Far complex in Saccharomyces cerevisiae.
    Pracheil T; Thornton J; Liu Z
    Genetics; 2012 Apr; 190(4):1325-39. PubMed ID: 22298706
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dysfunction of Avo3, an essential component of target of rapamycin complex 2, induces ubiquitin-proteasome-dependent downregulation of Avo2 in Saccharomyces cerevisiae.
    Chen PK; Chang YJ; Chou YW; Chen MY
    Biochem Biophys Res Commun; 2024 Jul; 717():150045. PubMed ID: 38718572
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cryo-EM structure of human mTOR complex 2.
    Chen X; Liu M; Tian Y; Li J; Qi Y; Zhao D; Wu Z; Huang M; Wong CCL; Wang HW; Wang J; Yang H; Xu Y
    Cell Res; 2018 May; 28(5):518-528. PubMed ID: 29567957
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Tor forms a dimer through an N-terminal helical solenoid with a complex topology.
    Baretić D; Berndt A; Ohashi Y; Johnson CM; Williams RL
    Nat Commun; 2016 Apr; 7():11016. PubMed ID: 27072897
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Evolutionary conservation of TORC1 components, TOR, Raptor, and LST8, between rice and yeast.
    Maegawa K; Takii R; Ushimaru T; Kozaki A
    Mol Genet Genomics; 2015 Oct; 290(5):2019-30. PubMed ID: 25956502
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structures of the pleckstrin homology domain of Saccharomyces cerevisiae Avo1 and its human orthologue Sin1, an essential subunit of TOR complex 2.
    Pan D; Matsuura Y
    Acta Crystallogr Sect F Struct Biol Cryst Commun; 2012 Apr; 68(Pt 4):386-92. PubMed ID: 22505404
    [TBL] [Abstract][Full Text] [Related]  

  • 16. TORC2 plasma membrane localization is essential for cell viability and restricted to a distinct domain.
    Berchtold D; Walther TC
    Mol Biol Cell; 2009 Mar; 20(5):1565-75. PubMed ID: 19144819
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Involvement of Saccharomyces cerevisiae Avo3p/Tsc11p in maintaining TOR complex 2 integrity and coupling to downstream signaling.
    Ho HL; Lee HY; Liao HC; Chen MY
    Eukaryot Cell; 2008 Aug; 7(8):1328-43. PubMed ID: 18552287
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Evolutionary Conservation of the Components in the TOR Signaling Pathways.
    Tatebe H; Shiozaki K
    Biomolecules; 2017 Nov; 7(4):. PubMed ID: 29104218
    [TBL] [Abstract][Full Text] [Related]  

  • 19. TORC2 Structure and Function.
    Gaubitz C; Prouteau M; Kusmider B; Loewith R
    Trends Biochem Sci; 2016 Jun; 41(6):532-545. PubMed ID: 27161823
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of defined structural elements within TOR2 kinase required for TOR complex 2 assembly and function in
    Tsverov J; Yegorov K; Powers T
    Mol Biol Cell; 2022 May; 33(5):ar44. PubMed ID: 35293776
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.