295 related articles for article (PubMed ID: 29174815)
1. Design, synthesis, and biological evaluation of 1,3-diarylisoquinolines as novel topoisomerase I catalytic inhibitors.
Khadka DB; Park S; Jin Y; Han J; Kwon Y; Cho WJ
Eur J Med Chem; 2018 Jan; 143():200-215. PubMed ID: 29174815
[TBL] [Abstract][Full Text] [Related]
2. Modification of 3-arylisoquinolines into 3,4-diarylisoquinolines and assessment of their cytotoxicity and topoisomerase inhibition.
Khadka DB; Woo H; Yang SH; Zhao C; Jin Y; Le TN; Kwon Y; Cho WJ
Eur J Med Chem; 2015 Mar; 92():583-607. PubMed ID: 25613224
[TBL] [Abstract][Full Text] [Related]
3. Design, synthesis and systematic evaluation of cytotoxic 3-heteroarylisoquinolinamines as topoisomerases inhibitors.
My Van HT; Woo H; Jeong HM; Khadka DB; Yang SH; Zhao C; Jin Y; Lee ES; Youl Lee K; Kwon Y; Cho WJ
Eur J Med Chem; 2014 Jul; 82():181-94. PubMed ID: 24904965
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and biological evaluations of novel indenoisoquinolines as topoisomerase I inhibitors.
Zhang X; Wang R; Zhao L; Lu N; Wang J; You Q; Li Z; Guo Q
Bioorg Med Chem Lett; 2012 Jan; 22(2):1276-81. PubMed ID: 22079759
[TBL] [Abstract][Full Text] [Related]
5. Design, synthesis, topoisomerase I & II inhibitory activity, antiproliferative activity, and structure-activity relationship study of pyrazoline derivatives: An ATP-competitive human topoisomerase IIα catalytic inhibitor.
Ahmad P; Woo H; Jun KY; Kadi AA; Abdel-Aziz HA; Kwon Y; Rahman AF
Bioorg Med Chem; 2016 Apr; 24(8):1898-908. PubMed ID: 26988802
[TBL] [Abstract][Full Text] [Related]
6. Design, synthesis and antitumor activity of non-camptothecin topoisomerase I inhibitors.
Zhang C; Li S; Ji L; Liu S; Li Z; Li S; Meng X
Bioorg Med Chem Lett; 2015 Oct; 25(20):4693-6. PubMed ID: 26384290
[TBL] [Abstract][Full Text] [Related]
7. Synthesis of novel benzoxanthone analogues as non-Camptothecin topoisomerase I inhibitors.
Cheng P; Zhu L; Guo W; Liu W; Yao J; Dong G; Zhang Y; Zhuang C; Sheng C; Miao Z; Zhang W
J Enzyme Inhib Med Chem; 2012 Jun; 27(3):437-42. PubMed ID: 21770860
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and biological evaluation of benzo[a]phenazine derivatives as a dual inhibitor of topoisomerase I and II.
Zhuo ST; Li CY; Hu MH; Chen SB; Yao PF; Huang SL; Ou TM; Tan JH; An LK; Li D; Gu LQ; Huang ZS
Org Biomol Chem; 2013 Jun; 11(24):3989-4005. PubMed ID: 23657605
[TBL] [Abstract][Full Text] [Related]
9. Synthesis of benzo[3,4]azepino[1,2-b]isoquinolin-9-ones from 3-arylisoquinolines via ring closing metathesis and evaluation of topoisomerase I inhibitory activity, cytotoxicity and docking study.
Van HT; Khadka DB; Yang SH; Le TN; Cho SH; Zhao C; Lee IS; Kwon Y; Lee KT; Kim YC; Cho WJ
Bioorg Med Chem; 2011 Sep; 19(18):5311-20. PubMed ID: 21873069
[TBL] [Abstract][Full Text] [Related]
10. Design, synthesis and biological evaluation of lapachol derivatives possessing indole scaffolds as topoisomerase I inhibitors.
Zhang C; Qu Y; Niu B
Bioorg Med Chem; 2016 Nov; 24(22):5781-5786. PubMed ID: 27667553
[TBL] [Abstract][Full Text] [Related]
11. Design, synthesis and biological evaluation of 3-substituted indenoisoquinoline derivatives as topoisomerase I inhibitors.
Zhao Q; Xu X; Xie Z; Liu X; You Q; Guo Q; Zhong Y; Li Z
Bioorg Med Chem Lett; 2016 Feb; 26(3):1068-1072. PubMed ID: 26725027
[TBL] [Abstract][Full Text] [Related]
12. Rational design, synthesis, and evaluation of novel 2,4-Chloro- and Hydroxy-Substituted diphenyl Benzofuro[3,2-b]Pyridines: Non-intercalative catalytic topoisomerase I and II dual inhibitor.
Park S; Thapa Magar TB; Kadayat TM; Lee HJ; Bist G; Shrestha A; Lee ES; Kwon Y
Eur J Med Chem; 2017 Feb; 127():318-333. PubMed ID: 28068603
[TBL] [Abstract][Full Text] [Related]
13. Topoisomerase I-mediated DNA cleavage as a guide to the development of antitumor agents derived from the marine alkaloid lamellarin D: triester derivatives incorporating amino acid residues.
Tardy C; Facompré M; Laine W; Baldeyrou B; García-Gravalos D; Francesch A; Mateo C; Pastor A; Jiménez JA; Manzanares I; Cuevas C; Bailly C
Bioorg Med Chem; 2004 Apr; 12(7):1697-712. PubMed ID: 15028262
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and biological evaluation of novel 7-acyl homocamptothecins as Topoisomerase I inhibitors.
Liu W; Zhu L; Guo W; Zhuang C; Zhang Y; Sheng C; Cheng P; Yao J; Wang W; Dong G; Wang S; Miao Z; Zhang W
Eur J Med Chem; 2011 Jun; 46(6):2408-14. PubMed ID: 21463912
[TBL] [Abstract][Full Text] [Related]
15. Design, synthesis and biological evaluation of novel 7-alkylamino substituted benzo[a]phenazin derivatives as dual topoisomerase I/II inhibitors.
Yao BL; Mai YW; Chen SB; Xie HT; Yao PF; Ou TM; Tan JH; Wang HG; Li D; Huang SL; Gu LQ; Huang ZS
Eur J Med Chem; 2015 Mar; 92():540-53. PubMed ID: 25599951
[TBL] [Abstract][Full Text] [Related]
16. Novel securinine derivatives as topoisomerase I based antitumor agents.
Hou W; Wang ZY; Peng CK; Lin J; Liu X; Chang YQ; Xu J; Jiang RW; Lin H; Sun PH; Chen WM
Eur J Med Chem; 2016 Oct; 122():149-163. PubMed ID: 27344492
[TBL] [Abstract][Full Text] [Related]
17. Design, synthesis, and biological evaluation of novel benzo[6,7]indolo[3,4-c]isoquinolines as anticancer agents with topoisomerase I inhibition.
Sakai K; Soshima T; Hirose Y; Ishibashi F; Hirao S
Bioorg Med Chem Lett; 2024 May; 104():129710. PubMed ID: 38518997
[TBL] [Abstract][Full Text] [Related]
18. Novel diindoloazepinone derivatives as DNA minor groove binding agents with selective topoisomerase I inhibition: Design, synthesis, biological evaluation and docking studies.
Kadagathur M; Devi GP; Grewal P; Sigalapalli DK; Makhal PN; Banerjee UC; Bathini NB; Tangellamudi ND
Bioorg Chem; 2020 Jun; 99():103629. PubMed ID: 32272367
[TBL] [Abstract][Full Text] [Related]
19. Design, Synthesis and Structure-Activity Relationship Studies of Glycosylated Derivatives of Marine Natural Product Lamellarin D.
Zheng L; Gao T; Ge Z; Ma Z; Xu J; Ding W; Shen L
Eur J Med Chem; 2021 Mar; 214():113226. PubMed ID: 33582387
[TBL] [Abstract][Full Text] [Related]
20. 3-Arylisoquinolines as novel topoisomerase I inhibitors.
Khadka DB; Cho WJ
Bioorg Med Chem; 2011 Jan; 19(2):724-34. PubMed ID: 21095131
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]