BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

340 related articles for article (PubMed ID: 29175333)

  • 21. USP9X deubiquitylating enzyme maintains RAPTOR protein levels, mTORC1 signalling and proliferation in neural progenitors.
    Bridges CR; Tan MC; Premarathne S; Nanayakkara D; Bellette B; Zencak D; Domingo D; Gecz J; Murtaza M; Jolly LA; Wood SA
    Sci Rep; 2017 Mar; 7(1):391. PubMed ID: 28341829
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Cryo-EM insight into the structure of MTOR complex 1 and its interactions with Rheb and substrates.
    Chao LH; Avruch J
    F1000Res; 2019; 8():. PubMed ID: 30647914
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Weak membrane interactions allow Rheb to activate mTORC1 signaling without major lysosome enrichment.
    Angarola B; Ferguson SM
    Mol Biol Cell; 2019 Oct; 30(22):2750-2760. PubMed ID: 31532697
    [TBL] [Abstract][Full Text] [Related]  

  • 24. mTORC1-dependent and -independent regulation of stem cell renewal, differentiation, and mobilization.
    Gan B; Sahin E; Jiang S; Sanchez-Aguilera A; Scott KL; Chin L; Williams DA; Kwiatkowski DJ; DePinho RA
    Proc Natl Acad Sci U S A; 2008 Dec; 105(49):19384-9. PubMed ID: 19052232
    [TBL] [Abstract][Full Text] [Related]  

  • 25. RHEB is a potential therapeutic target in T cell acute lymphoblastic leukemia.
    Pham LT; Peng H; Ueno M; Kohno S; Kasada A; Hosomichi K; Sato T; Kurayoshi K; Kobayashi M; Tadokoro Y; Kasahara A; Shoulkamy MI; Xiao B; Worley PF; Takahashi C; Tajima A; Hirao A
    Biochem Biophys Res Commun; 2022 Sep; 621():74-79. PubMed ID: 35810594
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Coordination of Rheb lysosomal membrane interactions with mTORC1 activation.
    Angarola B; Ferguson SM
    F1000Res; 2020; 9():. PubMed ID: 32518628
    [TBL] [Abstract][Full Text] [Related]  

  • 27. IP3 3-kinase B controls hematopoietic stem cell homeostasis and prevents lethal hematopoietic failure in mice.
    Siegemund S; Rigaud S; Conche C; Broaten B; Schaffer L; Westernberg L; Head SR; Sauer K
    Blood; 2015 Apr; 125(18):2786-97. PubMed ID: 25788703
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Genetic dissection of Ragulator structure and function in amino acid-dependent regulation of mTORC1.
    Nada S; Okada M
    J Biochem; 2020 Dec; 168(6):621-632. PubMed ID: 32653916
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Adiponectin Enhances Quiescence Exit of Murine Hematopoietic Stem Cells and Hematopoietic Recovery Through mTORC1 Potentiation.
    Masamoto Y; Arai S; Sato T; Kubota N; Takamoto I; Kadowaki T; Kurokawa M
    Stem Cells; 2017 Jul; 35(7):1835-1848. PubMed ID: 28480607
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Rheb localized on the Golgi membrane activates lysosome-localized mTORC1 at the Golgi-lysosome contact site.
    Hao F; Kondo K; Itoh T; Ikari S; Nada S; Okada M; Noda T
    J Cell Sci; 2018 Jan; 131(3):. PubMed ID: 29222112
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Osteocyte-intrinsic mTORC1 signaling restrains trabecular bone accrual in mice.
    Liu Q; Liu C; Yang Y; Yang H; Chen J
    J Cell Biochem; 2018 Nov; 119(11):8743-8749. PubMed ID: 30160781
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Hepatic Leukemia Factor Maintains Quiescence of Hematopoietic Stem Cells and Protects the Stem Cell Pool during Regeneration.
    Komorowska K; Doyle A; Wahlestedt M; Subramaniam A; Debnath S; Chen J; Soneji S; Van Handel B; Mikkola HKA; Miharada K; Bryder D; Larsson J; Magnusson M
    Cell Rep; 2017 Dec; 21(12):3514-3523. PubMed ID: 29262330
    [TBL] [Abstract][Full Text] [Related]  

  • 33. A small molecule inhibitor of Rheb selectively targets mTORC1 signaling.
    Mahoney SJ; Narayan S; Molz L; Berstler LA; Kang SA; Vlasuk GP; Saiah E
    Nat Commun; 2018 Feb; 9(1):548. PubMed ID: 29416044
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Phospholipase D-dependent mTOR complex 1 (mTORC1) activation by glutamine.
    Bernfeld E; Menon D; Vaghela V; Zerin I; Faruque P; Frias MA; Foster DA
    J Biol Chem; 2018 Oct; 293(42):16390-16401. PubMed ID: 30194281
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Rheb1 loss leads to increased hematopoietic stem cell proliferation and myeloid-biased differentiation
    Wang X; Gao Y; Gao J; Li M; Zhou M; Wang J; Pang Y; Cheng H; Yuan C; Chu Y; Jiang Y; Zhou J; Luo HR; Ju Z; Cheng T; Yuan W
    Haematologica; 2019 Feb; 104(2):245-255. PubMed ID: 30262562
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Circadian Rheb oscillation alters the dynamics of hepatic mTORC1 activity and mitochondrial morphology.
    Yuan Q; Chen M; Yang W; Xiao B
    FEBS Lett; 2021 Feb; 595(3):360-369. PubMed ID: 33247956
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Twist-1, a novel regulator of hematopoietic stem cell self-renewal and myeloid lineage development.
    Dong CY; Liu XY; Wang N; Wang LN; Yang BX; Ren Q; Liang HY; Ma XT
    Stem Cells; 2014 Dec; 32(12):3173-82. PubMed ID: 25100001
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Regulation of mTORC1 by PI3K signaling.
    Dibble CC; Cantley LC
    Trends Cell Biol; 2015 Sep; 25(9):545-55. PubMed ID: 26159692
    [TBL] [Abstract][Full Text] [Related]  

  • 39. The FBXW7-SHOC2-Raptor Axis Controls the Cross-Talks between the RAS-ERK and mTORC1 Signaling Pathways.
    Xie CM; Tan M; Lin XT; Wu D; Jiang Y; Tan Y; Li H; Ma Y; Xiong X; Sun Y
    Cell Rep; 2019 Mar; 26(11):3037-3050.e4. PubMed ID: 30865892
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Rheb mediates neuronal-activity-induced mitochondrial energetics through mTORC1-independent PDH activation.
    Yang W; Pang D; Chen M; Du C; Jia L; Wang L; He Y; Jiang W; Luo L; Yu Z; Mao M; Yuan Q; Tang P; Xia X; Cui Y; Jing B; Platero A; Liu Y; Wei Y; Worley PF; Xiao B
    Dev Cell; 2021 Mar; 56(6):811-825.e6. PubMed ID: 33725483
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 17.