BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

478 related articles for article (PubMed ID: 29178024)

  • 1. Does EGFR Mutation Type Influence Patient-Reported Outcomes in Patients with Advanced EGFR Mutation-Positive Non-Small-Cell Lung Cancer? Analysis of Two Large, Phase III Studies Comparing Afatinib with Chemotherapy (LUX-Lung 3 and LUX-Lung 6).
    Wu YL; Hirsh V; Sequist LV; Hu CP; Feng J; Lu S; Huang Y; Schuler M; Mok T; Yamamoto N; O'Byrne K; Geater SL; Zhou C; Massey D; Märten A; Lungershausen J; Yang JC
    Patient; 2018 Feb; 11(1):131-141. PubMed ID: 29178024
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Afatinib versus cisplatin plus pemetrexed in Japanese patients with advanced non-small cell lung cancer harboring activating EGFR mutations: Subgroup analysis of LUX-Lung 3.
    Kato T; Yoshioka H; Okamoto I; Yokoyama A; Hida T; Seto T; Kiura K; Massey D; Seki Y; Yamamoto N
    Cancer Sci; 2015 Sep; 106(9):1202-11. PubMed ID: 26094656
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Afatinib in the first-line treatment of epidermal-growth-factor-receptor mutation-positive non-small cell lung cancer: a review of the clinical evidence.
    Ke EE; Wu YL
    Ther Adv Respir Dis; 2016 Jun; 10(3):256-64. PubMed ID: 26929305
    [TBL] [Abstract][Full Text] [Related]  

  • 4. First-Line Afatinib versus Chemotherapy in Patients with Non-Small Cell Lung Cancer and Common Epidermal Growth Factor Receptor Gene Mutations and Brain Metastases.
    Schuler M; Wu YL; Hirsh V; O'Byrne K; Yamamoto N; Mok T; Popat S; Sequist LV; Massey D; Zazulina V; Yang JC
    J Thorac Oncol; 2016 Mar; 11(3):380-90. PubMed ID: 26823294
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Symptom control and quality of life in LUX-Lung 3: a phase III study of afatinib or cisplatin/pemetrexed in patients with advanced lung adenocarcinoma with EGFR mutations.
    Yang JC; Hirsh V; Schuler M; Yamamoto N; O'Byrne KJ; Mok TS; Zazulina V; Shahidi M; Lungershausen J; Massey D; Palmer M; Sequist LV
    J Clin Oncol; 2013 Sep; 31(27):3342-50. PubMed ID: 23816967
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Symptom and Quality of Life Improvement in LUX-Lung 8, an Open-Label Phase III Study of Second-Line Afatinib Versus Erlotinib in Patients With Advanced Squamous Cell Carcinoma of the Lung After First-Line Platinum-Based Chemotherapy.
    Felip E; Hirsh V; Popat S; Cobo M; Fülöp A; Dayen C; Trigo JM; Gregg R; Waller CF; Soria JC; Goss GD; Gordon J; Wang B; Palmer M; Ehrnrooth E; Gadgeel SM
    Clin Lung Cancer; 2018 Jan; 19(1):74-83.e11. PubMed ID: 28729180
    [TBL] [Abstract][Full Text] [Related]  

  • 7. [Afatinib as first-line therapy in mutation-positive EGFR. Results by type of mutation].
    Vidal ÓJ
    Med Clin (Barc); 2016 Apr; 146 Suppl 1():12-8. PubMed ID: 27426243
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Symptom and quality of life benefit of afatinib in advanced non-small-cell lung cancer patients previously treated with erlotinib or gefitinib: results of a randomized phase IIb/III trial (LUX-Lung 1).
    Hirsh V; Cadranel J; Cong XJ; Fairclough D; Finnern HW; Lorence RM; Miller VA; Palmer M; Yang JC
    J Thorac Oncol; 2013 Feb; 8(2):229-37. PubMed ID: 23328549
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Symptom and Quality of Life Improvement in LUX-Lung 6: An Open-Label Phase III Study of Afatinib Versus Cisplatin/Gemcitabine in Asian Patients With EGFR Mutation-Positive Advanced Non-small-cell Lung Cancer.
    Geater SL; Xu CR; Zhou C; Hu CP; Feng J; Lu S; Huang Y; Li W; Hou M; Shi JH; Lee KY; Palmer M; Shi Y; Lungershausen J; Wu YL
    J Thorac Oncol; 2015 Jun; 10(6):883-9. PubMed ID: 25933111
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Afatinib versus gefitinib in patients with EGFR mutation-positive advanced non-small-cell lung cancer: overall survival data from the phase IIb LUX-Lung 7 trial.
    Paz-Ares L; Tan EH; O'Byrne K; Zhang L; Hirsh V; Boyer M; Yang JC; Mok T; Lee KH; Lu S; Shi Y; Lee DH; Laskin J; Kim DW; Laurie SA; Kölbeck K; Fan J; Dodd N; Märten A; Park K
    Ann Oncol; 2017 Feb; 28(2):270-277. PubMed ID: 28426106
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Advanced non-small cell lung cancer (NSCLC) with activating EGFR mutations: first-line treatment with afatinib and other EGFR TKIs.
    Brückl W; Tufman A; Huber RM
    Expert Rev Anticancer Ther; 2017 Feb; 17(2):143-155. PubMed ID: 27898252
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Comparison of Gefitinib Versus Chemotherapy in Patients with Non-small Cell Lung Cancer with Exon 19 Deletion.
    Watanabe S; Inoue A; Nukiwa T; Kobayashi K
    Anticancer Res; 2015 Dec; 35(12):6957-61. PubMed ID: 26637922
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Distinct Benefit of Overall Survival between Patients with Non-Small-Cell Lung Cancer Harboring EGFR Exon 19 Deletion and Exon 21 L858R Substitution.
    Koyama N; Watanabe Y; Iwai Y; Kawamura R; Miwa C; Nagai Y; Hagiwara K; Koyama S
    Chemotherapy; 2017; 62(3):151-158. PubMed ID: 28110331
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Clinical activity of afatinib in patients with advanced non-small-cell lung cancer harbouring uncommon EGFR mutations: a combined post-hoc analysis of LUX-Lung 2, LUX-Lung 3, and LUX-Lung 6.
    Yang JC; Sequist LV; Geater SL; Tsai CM; Mok TS; Schuler M; Yamamoto N; Yu CJ; Ou SH; Zhou C; Massey D; Zazulina V; Wu YL
    Lancet Oncol; 2015 Jul; 16(7):830-8. PubMed ID: 26051236
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Common EGFR-mutated subgroups (Del19/L858R) in advanced non-small-cell lung cancer: chasing better outcomes with tyrosine kinase inhibitors.
    Reguart N; Remon J
    Future Oncol; 2015; 11(8):1245-57. PubMed ID: 25629371
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Budget Impact Analysis of Afatinib for First-Line Treatment of Patients with Metastatic Non-Small Cell Lung Cancer with Epidermal Growth Factor Receptor Exon 19 Deletions or Exon 21 Substitution Mutations in a U.S. Health Plan.
    Graham J; Earnshaw S; Burslem K; Lim J
    J Manag Care Spec Pharm; 2018 Jun; 24(6):544-553. PubMed ID: 29799327
    [TBL] [Abstract][Full Text] [Related]  

  • 17. [Efficacy of first-line afatinib versus chemotherapy in EGFR mutation positive pulmonary adenocarcinoma].
    Sárosi V; Balikó Z
    Magy Onkol; 2014 Dec; 58(4):325-9. PubMed ID: 25517450
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cost-Effectiveness and Value of Information of Erlotinib, Afatinib, and Cisplatin-Pemetrexed for First-Line Treatment of Advanced EGFR Mutation-Positive Non-Small-Cell Lung Cancer in the United States.
    Ting J; Tien Ho P; Xiang P; Sugay A; Abdel-Sattar M; Wilson L
    Value Health; 2015 Sep; 18(6):774-82. PubMed ID: 26409604
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Afatinib versus cisplatin-based chemotherapy for EGFR mutation-positive lung adenocarcinoma (LUX-Lung 3 and LUX-Lung 6): analysis of overall survival data from two randomised, phase 3 trials.
    Yang JC; Wu YL; Schuler M; Sebastian M; Popat S; Yamamoto N; Zhou C; Hu CP; O'Byrne K; Feng J; Lu S; Huang Y; Geater SL; Lee KY; Tsai CM; Gorbunova V; Hirsh V; Bennouna J; Orlov S; Mok T; Boyer M; Su WC; Lee KH; Kato T; Massey D; Shahidi M; Zazulina V; Sequist LV
    Lancet Oncol; 2015 Feb; 16(2):141-51. PubMed ID: 25589191
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The role of smoking status on the progression-free survival of non-small cell lung cancer patients harboring activating epidermal growth factor receptor (EGFR) mutations receiving first-line EGFR tyrosine kinase inhibitor versus platinum doublet chemotherapy: a meta-analysis of prospective randomized trials.
    Hasegawa Y; Ando M; Maemondo M; Yamamoto S; Isa S; Saka H; Kubo A; Kawaguchi T; Takada M; Rosell R; Kurata T; Ou SH
    Oncologist; 2015 Mar; 20(3):307-15. PubMed ID: 25657199
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.