BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

147 related articles for article (PubMed ID: 29178779)

  • 1. Synthesis of bis-Phosphate Iminoaltritol Enantiomers and Structural Characterization with Adenine Phosphoribosyltransferase.
    Harris LD; Harijan RK; Ducati RG; Evans GB; Hirsch BM; Schramm VL
    ACS Chem Biol; 2018 Jan; 13(1):152-160. PubMed ID: 29178779
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Adenine phosphoribosyltransferase from Sulfolobus solfataricus is an enzyme with unusual kinetic properties and a crystal structure that suggests it evolved from a 6-oxopurine phosphoribosyltransferase.
    Jensen KF; Hansen MR; Jensen KS; Christoffersen S; Poulsen JC; Mølgaard A; Kadziola A
    Biochemistry; 2015 Apr; 54(14):2323-34. PubMed ID: 25790177
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Transition state analogues of Plasmodium falciparum and human orotate phosphoribosyltransferases.
    Zhang Y; Evans GB; Clinch K; Crump DR; Harris LD; Fröhlich RF; Tyler PC; Hazleton KZ; Cassera MB; Schramm VL
    J Biol Chem; 2013 Nov; 288(48):34746-54. PubMed ID: 24158442
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Purification and characterization of adenine phosphoribosyltransferase from Saccharomyces cerevisiae.
    Alfonzo JD; Sahota A; Taylor MW
    Biochim Biophys Acta; 1997 Sep; 1341(2):173-82. PubMed ID: 9357956
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 'Irreversible' slow-onset inhibition of orotate phosphoribosyltransferase by an amidrazone phosphate transition-state mimic.
    Witte JF; Bray KE; Thornburg CK; McClard RW
    Bioorg Med Chem Lett; 2006 Dec; 16(23):6112-5. PubMed ID: 16979338
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural complexes of human adenine phosphoribosyltransferase reveal novel features of the APRT catalytic mechanism.
    Silva CH; Silva M; Iulek J; Thiemann OH
    J Biomol Struct Dyn; 2008 Jun; 25(6):589-97. PubMed ID: 18399692
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The 2.0 A structure of malarial purine phosphoribosyltransferase in complex with a transition-state analogue inhibitor.
    Shi W; Li CM; Tyler PC; Furneaux RH; Cahill SM; Girvin ME; Grubmeyer C; Schramm VL; Almo SC
    Biochemistry; 1999 Aug; 38(31):9872-80. PubMed ID: 10433693
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural analysis of adenine phosphoribosyltransferase from Saccharomyces cerevisiae.
    Shi W; Tanaka KS; Crother TR; Taylor MW; Almo SC; Schramm VL
    Biochemistry; 2001 Sep; 40(36):10800-9. PubMed ID: 11535055
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Human malaria parasite orotate phosphoribosyltransferase: functional expression, characterization of kinetic reaction mechanism and inhibition profile.
    Krungkrai SR; Aoki S; Palacpac NM; Sato D; Mitamura T; Krungkrai J; Horii T
    Mol Biochem Parasitol; 2004 Apr; 134(2):245-55. PubMed ID: 15003844
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural Insights into the Forward and Reverse Enzymatic Reactions in Human Adenine Phosphoribosyltransferase.
    Huyet J; Ozeir M; Burgevin MC; Pinson B; Chesney F; Remy JM; Siddiqi AR; Lupoli R; Pinon G; Saint-Marc C; Gibert JF; Morales R; Ceballos-Picot I; Barouki R; Daignan-Fornier B; Olivier-Bandini A; Augé F; Nioche P
    Cell Chem Biol; 2018 Jun; 25(6):666-676.e4. PubMed ID: 29576532
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pyrophosphate interactions at the transition states of Plasmodium falciparum and human orotate phosphoribosyltransferases.
    Zhang Y; Schramm VL
    J Am Chem Soc; 2010 Jun; 132(25):8787-94. PubMed ID: 20527751
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Closed site complexes of adenine phosphoribosyltransferase from Giardia lamblia reveal a mechanism of ribosyl migration.
    Shi W; Sarver AE; Wang CC; Tanaka KS; Almo SC; Schramm VL
    J Biol Chem; 2002 Oct; 277(42):39981-8. PubMed ID: 12171925
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Half-of-sites binding of orotidine 5'-phosphate and alpha-D-5-phosphorylribose 1-diphosphate to orotate phosphoribosyltransferase from Saccharomyces cerevisiae supports a novel variant of the Theorell-Chance mechanism with alternating site catalysis.
    McClard RW; Holets EA; MacKinnon AL; Witte JF
    Biochemistry; 2006 Apr; 45(16):5330-42. PubMed ID: 16618122
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Transition states of Plasmodium falciparum and human orotate phosphoribosyltransferases.
    Zhang Y; Luo M; Schramm VL
    J Am Chem Soc; 2009 Apr; 131(13):4685-94. PubMed ID: 19292447
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Adenine metabolism in Plasmodium falciparum.
    Mehrotra S; Bopanna MP; Bulusu V; Balaram H
    Exp Parasitol; 2010 Jun; 125(2):147-51. PubMed ID: 20093117
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Crystallization of the purine salvage enzyme adenine phosphoribosyltransferase.
    Phillíps CL; Ullman B; Brennan RG
    Proteins; 1996 Aug; 25(4):510-3. PubMed ID: 8865346
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Crystal structures of adenine phosphoribosyltransferase from Leishmania donovani.
    Phillips CL; Ullman B; Brennan RG; Hill CP
    EMBO J; 1999 Jul; 18(13):3533-45. PubMed ID: 10393170
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Crystal structures of APRT from Francisella tularensis - an N-H···N hydrogen bond imparts adenine specificity in adenine phosporibosyltransferases.
    Pavithra GC; Ramagopal UA
    FEBS J; 2018 Jun; 285(12):2306-2318. PubMed ID: 29694705
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Crystal structure of adenine phosphoribosyltransferase from Leishmania tarentolae: potential implications for APRT catalytic mechanism.
    Silva M; Silva CH; Iulek J; Oliva G; Thiemann OH
    Biochim Biophys Acta; 2004 Jan; 1696(1):31-9. PubMed ID: 14726202
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Crystal structures of Giardia lamblia guanine phosphoribosyltransferase at 1.75 A(,).
    Shi W; Munagala NR; Wang CC; Li CM; Tyler PC; Furneaux RH; Grubmeyer C; Schramm VL; Almo SC
    Biochemistry; 2000 Jun; 39(23):6781-90. PubMed ID: 10841757
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.