These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
120 related articles for article (PubMed ID: 29180684)
1. Systemic clearance and brain distribution of carbazole-based cyanine compounds as Alzheimer's disease drug candidates. Zhou W; Hu X; Tam KY Sci Rep; 2017 Nov; 7(1):16368. PubMed ID: 29180684 [TBL] [Abstract][Full Text] [Related]
2. SLOH, a carbazole-based fluorophore, mitigates neuropathology and behavioral impairment in the triple-transgenic mouse model of Alzheimer's disease. Wu X; Kosaraju J; Zhou W; Tam KY Neuropharmacology; 2018 Mar; 131():351-363. PubMed ID: 29309769 [TBL] [Abstract][Full Text] [Related]
3. Neuroprotective Effect of SLM, a Novel Carbazole-Based Fluorophore, on SH-SY5Y Cell Model and 3xTg-AD Mouse Model of Alzheimer's Disease. Wu X; Kosaraju J; Zhou W; Tam KY ACS Chem Neurosci; 2017 Mar; 8(3):676-685. PubMed ID: 28032988 [TBL] [Abstract][Full Text] [Related]
4. Prediction of in vivo rat biliary drug clearance from an in vitro hepatocyte efflux model. Lundquist P; Lööf J; Fagerholm U; Sjögren I; Johansson J; Briem S; Hoogstraate J; Afzelius L; Andersson TB Drug Metab Dispos; 2014 Mar; 42(3):459-68. PubMed ID: 24396143 [TBL] [Abstract][Full Text] [Related]
5. Ability of carbazole salts, inhibitors of Alzheimer beta-amyloid fibril formation, to cross cellular membranes. Saengkhae C; Salerno M; Adès D; Siove A; Le Moyec L; Migonney V; Garnier-Suillerot A Eur J Pharmacol; 2007 Mar; 559(2-3):124-31. PubMed ID: 17291491 [TBL] [Abstract][Full Text] [Related]
6. Mechanistic insights from comparing intrinsic clearance values between human liver microsomes and hepatocytes to guide drug design. Di L; Keefer C; Scott DO; Strelevitz TJ; Chang G; Bi YA; Lai Y; Duckworth J; Fenner K; Troutman MD; Obach RS Eur J Med Chem; 2012 Nov; 57():441-8. PubMed ID: 22840492 [TBL] [Abstract][Full Text] [Related]
7. Anti-neuroinflammatory effects of SLOH in Aβ-induced BV-2 microglial cells and 3xTg-AD mice involve the inhibition of GSK-3β. Wu X; Kosaraju J; Tam KY Neurosci Lett; 2018 Nov; 687():207-215. PubMed ID: 30278248 [TBL] [Abstract][Full Text] [Related]
8. Age-Dependent Regulation of the Blood-Brain Barrier Influx/Efflux Equilibrium of Amyloid-β Peptide in a Mouse Model of Alzheimer's Disease (3xTg-AD). Do TM; Dodacki A; Alata W; Calon F; Nicolic S; Scherrmann JM; Farinotti R; Bourasset F J Alzheimers Dis; 2016; 49(2):287-300. PubMed ID: 26484906 [TBL] [Abstract][Full Text] [Related]
9. Relationship between passive permeability, efflux, and predictability of clearance from in vitro metabolic intrinsic clearance. Huang L; Berry L; Ganga S; Janosky B; Chen A; Roberts J; Colletti AE; Lin MH Drug Metab Dispos; 2010 Feb; 38(2):223-31. PubMed ID: 19875499 [TBL] [Abstract][Full Text] [Related]
10. Quantitative evaluation of the impact of active efflux by p-glycoprotein and breast cancer resistance protein at the blood-brain barrier on the predictability of the unbound concentrations of drugs in the brain using cerebrospinal fluid concentration as a surrogate. Kodaira H; Kusuhara H; Fujita T; Ushiki J; Fuse E; Sugiyama Y J Pharmacol Exp Ther; 2011 Dec; 339(3):935-44. PubMed ID: 21934030 [TBL] [Abstract][Full Text] [Related]
11. Oleocanthal enhances amyloid-β clearance from the brains of TgSwDI mice and in vitro across a human blood-brain barrier model. Qosa H; Batarseh YS; Mohyeldin MM; El Sayed KA; Keller JN; Kaddoumi A ACS Chem Neurosci; 2015 Nov; 6(11):1849-59. PubMed ID: 26348065 [TBL] [Abstract][Full Text] [Related]
12. Importance of Hepatic Transporters in Clinical Disposition of Drugs and Their Metabolites. Patel M; Taskar KS; Zamek-Gliszczynski MJ J Clin Pharmacol; 2016 Jul; 56 Suppl 7():S23-39. PubMed ID: 27385177 [TBL] [Abstract][Full Text] [Related]
13. Pharmacokinetic analysis of the blood-brain barrier transport of 125I-amyloid beta protein 40 in wild-type and Alzheimer's disease transgenic mice (APP,PS1) and its implications for amyloid plaque formation. Kandimalla KK; Curran GL; Holasek SS; Gilles EJ; Wengenack TM; Poduslo JF J Pharmacol Exp Ther; 2005 Jun; 313(3):1370-8. PubMed ID: 15743932 [TBL] [Abstract][Full Text] [Related]
14. Strategies to improve the prediction accuracy of hepatic intrinsic clearance of three antidiabetic drugs: Application of the extended clearance concept and consideration of the effect of albumin on CYP2C metabolism and OATP1B-mediated hepatic uptake. Fujino R; Hashizume K; Aoyama S; Maeda K; Ito K; Toshimoto K; Lee W; Ninomiya SI; Sugiyama Y Eur J Pharm Sci; 2018 Dec; 125():181-192. PubMed ID: 30287410 [TBL] [Abstract][Full Text] [Related]
15. Temsirolimus promotes autophagic clearance of amyloid-β and provides protective effects in cellular and animal models of Alzheimer's disease. Jiang T; Yu JT; Zhu XC; Tan MS; Wang HF; Cao L; Zhang QQ; Shi JQ; Gao L; Qin H; Zhang YD; Tan L Pharmacol Res; 2014 Mar; 81():54-63. PubMed ID: 24602800 [TBL] [Abstract][Full Text] [Related]
16. Role of P-glycoprotein and permeability upon the brain distribution and pharmacodynamics of etamicastat: a comparison with nepicastat. Loureiro AI; Bonifácio MJ; Fernandes-Lopes C; Pires N; Igreja B; Wright LC; Soares-da-Silva P Xenobiotica; 2015; 45(9):828-39. PubMed ID: 25915108 [TBL] [Abstract][Full Text] [Related]
17. Preclinical pharmacokinetics and in vitro metabolism of dasatinib (BMS-354825): a potent oral multi-targeted kinase inhibitor against SRC and BCR-ABL. Kamath AV; Wang J; Lee FY; Marathe PH Cancer Chemother Pharmacol; 2008 Mar; 61(3):365-76. PubMed ID: 17429625 [TBL] [Abstract][Full Text] [Related]
18. The potential of Sutherlandia frutescens for herb-drug interaction. Fasinu PS; Gutmann H; Schiller H; James AD; Bouic PJ; Rosenkranz B Drug Metab Dispos; 2013 Feb; 41(2):488-97. PubMed ID: 23209194 [TBL] [Abstract][Full Text] [Related]
19. Nanoformulated alpha-mangostin ameliorates Alzheimer's disease neuropathology by elevating LDLR expression and accelerating amyloid-beta clearance. Yao L; Gu X; Song Q; Wang X; Huang M; Hu M; Hou L; Kang T; Chen J; Chen H; Gao X J Control Release; 2016 Mar; 226():1-14. PubMed ID: 26836197 [TBL] [Abstract][Full Text] [Related]
20. Sigmoidal kinetics of CYP3A substrates: an approach for scaling dextromethorphan metabolism in hepatic microsomes and isolated hepatocytes to predict in vivo clearance in rat. Witherow LE; Houston JB J Pharmacol Exp Ther; 1999 Jul; 290(1):58-65. PubMed ID: 10381760 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]