BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

177 related articles for article (PubMed ID: 29186656)

  • 1. Conformational Preference and Fluorescence Response of a C-Linked C8-Biphenyl-Guanine Lesion in the NarI Mutational Hotspot: Evidence for Enhanced Syn Adduct Formation.
    Berger FD; Sturla SJ; Kung RW; Montina T; Wetmore SD; Manderville RA
    Chem Res Toxicol; 2018 Jan; 31(1):37-47. PubMed ID: 29186656
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Adduct Fluorescence as a Tool to Decipher Sequence Impact on Frameshift Mutations Mediated by a C-Linked C8-Biphenyl-Guanine Lesion.
    Berger FD; Manderville RA; Sturla SJ
    Chem Res Toxicol; 2019 Apr; 32(4):784-791. PubMed ID: 30785283
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural and biochemical impact of C8-aryl-guanine adducts within the NarI recognition DNA sequence: influence of aryl ring size on targeted and semi-targeted mutagenicity.
    Sproviero M; Verwey AM; Rankin KM; Witham AA; Soldatov DV; Manderville RA; Fekry MI; Sturla SJ; Sharma P; Wetmore SD
    Nucleic Acids Res; 2014 Dec; 42(21):13405-21. PubMed ID: 25361967
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Chlorine functionalization of a model phenolic C8-guanine adduct increases conformational rigidity and blocks extension by a Y-family DNA polymerase.
    Witham AA; Verwey AM; Sproviero M; Manderville RA; Sharma P; Wetmore SD
    Chem Res Toxicol; 2015 Jun; 28(6):1346-56. PubMed ID: 26004422
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Understanding the Mutagenicity of O-Linked and C-Linked Guanine DNA Adducts: A Combined Experimental and Computational Approach.
    Manderville RA; Wetmore SD
    Chem Res Toxicol; 2017 Jan; 30(1):177-188. PubMed ID: 27768845
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Enhancing Bulge Stabilization through Linear Extension of C8-Aryl-Guanine Adducts to Promote Polymerase Blockage or Strand Realignment to Produce a C:C Mismatch.
    Sproviero M; Verwey AM; Witham AA; Manderville RA; Sharma P; Wetmore SD
    Chem Res Toxicol; 2015 Aug; 28(8):1647-58. PubMed ID: 26225720
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mutagenicity of Ochratoxin A: Role for a Carbon-Linked C8-Deoxyguanosine Adduct?
    Manderville RA; Wetmore SD
    J Agric Food Chem; 2017 Aug; 65(33):7097-7105. PubMed ID: 28830149
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Solution structure of the aminofluorene [AF]-external conformer of the anti-[AF]-C8-dG adduct opposite dC in a DNA duplex.
    Mao B; Hingerty BE; Broyde S; Patel DJ
    Biochemistry; 1998 Jan; 37(1):95-106. PubMed ID: 9425029
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Solution conformation of [AF]dG opposite a -2 deletion site in a DNA duplex: intercalation of the covalently attached aminofluorene ring into the helix with base displacement of the C8-modified syn guanine and adjacent unpaired 3'-adenine into the major groove.
    Mao B; Hingerty BE; Broyde S; Patel DJ
    Biochemistry; 1995 Dec; 34(51):16641-53. PubMed ID: 8527437
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural influence of C8-phenoxy-guanine in the NarI recognition DNA sequence.
    Kuska MS; Witham AA; Sproviero M; Manderville RA; Majdi Yazdi M; Sharma P; Wetmore SD
    Chem Res Toxicol; 2013 Sep; 26(9):1397-408. PubMed ID: 23984847
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Solution structure of the aminofluorene-intercalated conformer of the syn [AF]-C8-dG adduct opposite a--2 deletion site in the NarI hot spot sequence context.
    Mao B; Gorin A; Gu Z; Hingerty BE; Broyde S; Patel DJ
    Biochemistry; 1997 Nov; 36(47):14479-90. PubMed ID: 9398167
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Influence of the linkage type and functional groups in the carcinogenic moiety on the conformational preferences of damaged DNA: structural and energetic characterization of carbon- and oxygen-linked C(8)-phenolic-guanine adducts.
    Sharma P; Majdi Yazdi M; Merriman A; Manderville RA; Wetmore SD
    Chem Res Toxicol; 2015 Apr; 28(4):782-96. PubMed ID: 25658653
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structure of an Unusual Tetracyclic Deoxyguanosine Adduct: Implications for Frameshift Mutagenicity of
    Manning TW; Al-Abdul-Wahid MS; Manderville RA; Josephy PD; Kung RW; Wetmore SD
    Chem Res Toxicol; 2020 Feb; 33(2):584-593. PubMed ID: 31885260
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Base-Displaced Intercalated Structure of the N-(2'-Deoxyguanosin-8-yl)-3-aminobenzanthrone DNA Adduct.
    Politica DA; Malik CK; Basu AK; Stone MP
    Chem Res Toxicol; 2015 Dec; 28(12):2253-66. PubMed ID: 26641105
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular Modeling of the Major DNA Adduct Formed from Food Mutagen Ochratoxin A in NarI Two-Base Deletion Duplexes: Impact of Sequence Context and Adduct Ionization on Conformational Preference and Mutagenicity.
    Kathuria P; Sharma P; Manderville RA; Wetmore SD
    Chem Res Toxicol; 2017 Aug; 30(8):1582-1591. PubMed ID: 28719194
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Fluorescent properties and conformational preferences of C-linked phenolic-DNA adducts.
    Omumi A; Millen AL; Wetmore SD; Manderville RA
    Chem Res Toxicol; 2011 Oct; 24(10):1694-709. PubMed ID: 21905681
    [TBL] [Abstract][Full Text] [Related]  

  • 17. C8-heteroaryl-2'-deoxyguanosine adducts as conformational fluorescent probes in the NarI recognition sequence.
    Rankin KM; Sproviero M; Rankin K; Sharma P; Wetmore SD; Manderville RA
    J Org Chem; 2012 Dec; 77(23):10498-508. PubMed ID: 23171213
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Base-Displaced Intercalated Conformation of the 2-Amino-3-methylimidazo[4,5-f]quinoline N(2)-dG DNA Adduct Positioned at the Nonreiterated G(1) in the NarI Restriction Site.
    Stavros KM; Hawkins EK; Rizzo CJ; Stone MP
    Chem Res Toxicol; 2015 Jul; 28(7):1455-68. PubMed ID: 26083477
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Solution conformation of [AF]dG opposite a -1 deletion site in a DNA duplex: intercalation of the covalently attached aminofluorene ring into the helix with base displacement of the C8-modified Syn guanine into the major groove.
    Mao B; Cosman M; Hingerty BE; Broyde S; Patel DJ
    Biochemistry; 1995 May; 34(18):6226-38. PubMed ID: 7742328
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Solution structure of the aminofluorene [AF]-intercalated conformer of the syn-[AF]-C8-dG adduct opposite dC in a DNA duplex.
    Mao B; Hingerty BE; Broyde S; Patel DJ
    Biochemistry; 1998 Jan; 37(1):81-94. PubMed ID: 9425028
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.